Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice

por Götzl, Julia K., Colombo, Alessio-Vittorio, Fellerer, Katrin, Reifschneider, Anika, Werner, Georg, Tahirovic, Sabina, Haass, Christian, Capell, Anja
Publicado 2018

Loss of TMEM106B potentiates lysosomal and FTLD‐like pathology in progranulin‐deficient mice

por Werner, Georg, Damme, Markus, Schludi, Martin, Gnörich, Johannes, Wind, Karin, Fellerer, Katrin, Wefers, Benedikt, Wurst, Wolfgang, Edbauer, Dieter, Brendel, Matthias, Haass, Christian, Capell, Anja
Publicado 2020

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

por Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Schlepckow, Kai, Caballero, Miguel Ángel Araque, Franzmeier, Nicolai, Capell, Anja, Fellerer, Katrin, Nuscher, Brigitte, Eren, Erden, Levin, Johannes, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M., Cruchaga, Carlos, Shaw, Leslie M., Trojanowski, John Q., Weiner, Michael, Ewers, Michael, Haass, Christian
Publicado 2019

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

por Götzl, Julia K, Brendel, Matthias, Werner, Georg, Parhizkar, Samira, Sebastian Monasor, Laura, Kleinberger, Gernot, Colombo, Alessio‐Vittorio, Deussing, Maximilian, Wagner, Matias, Winkelmann, Juliane, Diehl‐Schmid, Janine, Levin, Johannes, Fellerer, Katrin, Reifschneider, Anika, Bultmann, Sebastian, Bartenstein, Peter, Rominger, Axel, Tahirovic, Sabina, Smith, Scott T, Madore, Charlotte, Butovsky, Oleg, Capell, Anja, Haass, Christian
Publicado 2019

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

por Suárez‐Calvet, Marc, Capell, Anja, Araque Caballero, Miguel Ángel, Morenas‐Rodríguez, Estrella, Fellerer, Katrin, Franzmeier, Nicolai, Kleinberger, Gernot, Eren, Erden, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M, Cruchaga, Carlos, Paumier, Katrina, Bateman, Randall J, Fagan, Anne M, Morris, John C, Levin, Johannes, Danek, Adrian, Jucker, Mathias, Masters, Colin L, Rossor, Martin N, Ringman, John M, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael, Ewers, Michael, Haass, Christian
Publicado 2018