Osr1 Is a Critical Regulator of Macrophage Polarization in NASH Progression

por Lee, Jin, Feng, Gen-Sheng
Publicado 2023

Modulation of the Nuclear Factor κb Pathway by Shp-2 Tyrosine Phosphatase in Mediating the Induction of Interleukin (Il)-6 by IL-1 or Tumor Necrosis Factor

por You, Min, Flick, Leah M., Yu, Dehua, Feng, Gen-Sheng
Publicado 2001

Macrophage Depletion Disrupts Immune Balance and Energy Homeostasis

por Lee, Bonggi, Qiao, Liping, Kinney, Brice, Feng, Gen-Sheng, Shao, Jianhua
Publicado 2014

Deletion of SHP-2 in mesenchymal stem cells causes growth retardation, limb and chest deformity, and calvarial defects in mice

por Lapinski, Philip E., Meyer, Melissa F., Feng, Gen-Sheng, Kamiya, Nobuhiro, King, Philip D.
Publicado 2013

Identification of CD133(+) intercellsomes in intercellular communication to offset intracellular signal deficit

por Kaneko, Kota, Liang, Yan, Liu, Qing, Zhang, Shuo, Scheiter, Alexander, Song, Dan, Feng, Gen-Sheng
Publicado 2023

The Unique Cysteine Knot Regulates the Pleotropic Hormone Leptin

por Haglund, Ellinor, Sułkowska, Joanna I., He, Zhao, Feng, Gen-Sheng, Jennings, Patricia A., Onuchic, José N.
Publicado 2012

Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages

por Du, Li, Ji, Yichun, Xin, Bing, Zhang, Jiemeng, Lu, Li-Chun, Glass, Christopher K., Feng, Gen-Sheng
Publicado 2023

Apolipoprotein A-I possesses an anti-obesity effect associated with increase of energy expenditure and up-regulation of UCP1 in brown fat

por Ruan, Xiangbo, Li, Zhenghu, Zhang, Yixuan, Yang, Ling, Pan, Yi, Wang, Zhenzhen, Feng, Gen-Sheng, Chen, Yan
Publicado 2011

Abnormal Chemokine-Induced Responses of Immature and Mature Hematopoietic Cells from Motheaten Mice Implicate the Protein Tyrosine Phosphatase Shp-1 in Chemokine Responses

por Kim, Chang H., Qu, Cheng-Kui, Hangoc, Giao, Cooper, Scott, Anzai, Naoyuki, Feng, Gen-Sheng, Broxmeyer, Hal E.
Publicado 1999

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis

por Garg, Ankur, Bansal, Mukesh, Gotoh, Noriko, Feng, Gen-Sheng, Zhong, Jian, Wang, Fen, Kariminejad, Ariana, Brooks, Steven, Zhang, Xin
Publicado 2017

Lens differentiation is controlled by the balance between PDGF and FGF signaling

por Li, Hongge, Mao, Yingyu, Bouaziz, Michael, Yu, Honglian, Qu, Xiuxia, Wang, Fen, Feng, Gen-Sheng, Shawber, Carrie, Zhang, Xin
Publicado 2019

High-fat Feeding Reprograms Maternal Energy Metabolism and Induces Long-term Postpartum Obesity in Mice

por Qiao, Liping, Chu, Kayee, Wattez, Jean-Sebastien, Lee, Samuel, Gao, Hongfei, Feng, Gen-Sheng, Hay, William W., Shao, Jianhua
Publicado 2019

Intermittent Cold Exposure Enhances Fat Accumulation in Mice

por Yoo, Hyung sun, Qiao, Liping, Bosco, Chris, Leong, Lok-Hei, Lytle, Nikki, Feng, Gen-Sheng, Chi, Nai-Wen, Shao, Jianhua
Publicado 2014

A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase

por Wu, Dongmei, Pang, Yuhong, Ke, Yuehai, Yu, Jianxiu, He, Zhao, Tautz, Lutz, Mustelin, Tomas, Ding, Sheng, Huang, Ziwei, Feng, Gen-Sheng
Publicado 2009

Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations

por Bauler, Timothy J., Kamiya, Nobuhiro, Lapinski, Philip E., Langewisch, Eric, Mishina, Yuji, Wilkinson, John E., Feng, Gen-Sheng, King, Philip D.
Publicado 2011

Tyrosine Phosphatase Shp2 Mediates the Estrogen Biological Action in Breast Cancer via Interaction with the Estrogen Extranuclear Receptor

por Li, Jun, Kang, Yujia, Wei, Longgang, Liu, Wenjie, Tian, Yingpu, Chen, Baozhen, Lin, Xiandong, Li, Yang, Feng, Gen-Sheng, Lu, Zhongxian
Publicado 2014

SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development

por Gagné-Sansfaçon, Jessica, Coulombe, Geneviève, Langlois, Marie-Josée, Langlois, Ariane, Paquet, Marilene, Carrier, Julie, Feng, Gen-Sheng, Qu, Cheng-Kui, Rivard, Nathalie
Publicado 2016

G(i)α proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells

por Wang, Zhanwei, Dela Cruz, Rica, Ji, Fang, Guo, Sheng, Zhang, Jianhua, Wang, Ying, Feng, Gen-Sheng, Birnbaumer, Lutz, Jiang, Meisheng, Chu, Wen-Ming
Publicado 2014

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice

por Liu, Wen, Guo, Wenjie, Shen, Lihong, Chen, Zhen, Luo, Qiong, Luo, Xiaolin, Feng, GenSheng, Shu, Yongqian, Gu, Yanhong, Xu, Qiang, Sun, Yang
Publicado 2016

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

por Guo, Wenjie, Liu, Wen, Chen, Zhen, Gu, Yanhong, Peng, Shuang, Shen, Lihong, Shen, Yan, Wang, Xingqi, Feng, Gen-Sheng, Sun, Yang, Xu, Qiang
Publicado 2017