Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 Has a Therapeutic Potential and Sensitizes Cisplatin in Nasopharyngeal Carcinoma

por Yang, Fen, Qian, Xiao-Jun, Qin, Wei, Deng, Rong, Wu, Xiao-Qi, Qin, Juan, Feng, Gong-Kan, Zhu, Xiao-Feng
Publicado 2013

c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

por Sun, Ting, Li, DanDan, Wang, LinLin, Xia, LiangPing, Ma, JianGuo, Guan, Zhong, Feng, GongKan, Zhu, XiaoFeng
Publicado 2011

Additional New Cytotoxic Triquinane-Type Sesquiterpenoids Chondrosterins K–M from the Marine Fungus Chondrostereum sp

por Huang, Lei, Lan, Wen-Jian, Deng, Rong, Feng, Gong-Kan, Xu, Qing-Yan, Hu, Zhi-Yu, Zhu, Xiao-Feng, Li, Hou-Jin
Publicado 2016

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

por Xu, Zeng, Huang, Lei, Chen, Xiao-Hong, Zhu, Xiao-Feng, Qian, Xiao-Jun, Feng, Gong-Kan, Lan, Wen-Jian, Li, Hou-Jin
Publicado 2014

Exploration of Indole Alkaloids from Marine Fungus Pseudallescheria boydii F44-1 Using an Amino Acid-Directed Strategy

por Yuan, Mei-Xiang, Qiu, Yi, Ran, Yan-Qin, Feng, Gong-Kan, Deng, Rong, Zhu, Xiao-Feng, Lan, Wen-Jian, Li, Hou-Jin
Publicado 2019

Monarubins A–C from the Marine Shellfish-Associated Fungus Monascus ruber BB5

por Ran, Yan-Qin, Lan, Wen-Jian, Qiu, Yi, Guo, Qi, Feng, Gong-Kan, Deng, Rong, Zhu, Xiao-Feng, Li, Hou-Jin, Dong, Jun
Publicado 2020

DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2

por Qin, Juan, Ji, Jiao, Deng, Rong, Tang, Jun, Yang, Fen, Feng, Gong-Kan, Chen, Wen-Dan, Wu, Xiao-Qi, Qian, Xiao-Jun, Ding, Ke, Zhu, Xiao-Feng
Publicado 2015

Cytotoxic alkaloids from the marine shellfish-associated fungus Aspergillus sp. XBB-4 induced by an amino acid-directed strategy

por Qiu, Yi, Guo, Qi, Ran, Yan-Qin, Lan, Wen-Jian, Lam, Chi-Keung, Feng, Gong-Kan, Deng, Rong, Zhu, Xiao-Feng, Li, Hou-Jin, Chen, Liu-Ping
Publicado 2020

Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: Hirsutano...

por Yang, Fen, Chen, Wen-Dan, Deng, Rong, Zhang, Hui, Tang, Jun, Wu, Ke-Wei, Li, Dan-Dan, Feng, Gong-Kan, Lan, Wen-Jian, Li, Hou-Jin, Zhu, Xiao-Feng
Publicado 2013

The Inhibition of Autophagy Sensitises Colon Cancer Cells with Wild-Type p53 but Not Mutant p53 to Topotecan Treatment

por Li, Dan-Dan, Sun, Ting, Wu, Xiao-Qi, Chen, Shu-Peng, Deng, Rong, Jiang, Shan, Feng, Gong-Kan, Pan, Jing-Xuan, Zhang, Xiao-Shi, Zeng, Yi-Xin, Zhu, Xiao-Feng
Publicado 2012

Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors

por Qian, Xiao-jun, Li, Yun-tian, Yu, Yan, Yang, Fen, Deng, Rong, Ji, Jiao, Jiao, Lin, Li, Xuan, Wu, Rui-Yan, Chen, Wen-Dan, Feng, Gong-Kan, Zhu, Xiao-Feng
Publicado 2015

Rhabdastrellic Acid-A Induced Autophagy-Associated Cell Death through Blocking Akt Pathway in Human Cancer Cells

por Li, Dan-Dan, Guo, Jing-Feng, Huang, Jia-Jia, Wang, Lin-Lin, Deng, Rong, Liu, Jian-Nan, Feng, Gong-Kan, Xiao, Ding-Jun, Deng, Song-Zhi, Zhang, Xiao-Shi, Zhu, Xiao-Feng
Publicado 2010

EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy

por Li, Yun-Tian, Qian, Xiao-Jun, Yu, Yan, Li, Zhen-Hua, Wu, Rui-Yan, Ji, Jiao, Jiao, Lin, Li, Xuan, Kong, Peng-Fei, Chen, Wen-Dan, Feng, Gong-Kan, Deng, Rong, Zhu, Xiao-Feng
Publicado 2015

Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth

por Sun, Ting, Li, Xuan, Zhang, Peng, Chen, Wen-Dan, Zhang, Hai-liang, Li, Dan-Dan, Deng, Rong, Qian, Xiao-Jun, Jiao, Lin, Ji, Jiao, Li, Yun-Tian, Wu, Rui-Yan, Yu, Yan, Feng, Gong-Kan, Zhu, Xiao-Feng
Publicado 2015

Loss of HRD functional phenotype impedes immunotherapy and can be reversed by HDAC inhibitor in ovarian cancer

por Yang, Dong, Huang, Fu-Xue, Wei, Wei, Li, Qia-Qia, Wu, Jun-Wan, Huang, Yun, Li, Zhi-Ling, Zhang, Hai-Liang, Li, Xuan, Yuan, Qiu-Er, Chen, Qing-shan, Feng, Gong-kan, Rong, Deng, Li, Jun-Dong, Zhu, Xiao-Feng
Publicado 2023

Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors

por Yang, Dong, Duan, Mei-Han, Yuan, Qiu-Er, Li, Zhi-Ling, Luo, Chuang-Hua, Cui, Lan-Yue, Li, Li-Chao, Xiao, Ying, Zhu, Xian-Ying, Zhang, Hai-Liang, Feng, Gong-Kan, Liu, Guo-Chen, Deng, Rong, Li, Jun-Dong, Zhu, Xiao-Feng
Publicado 2023

XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells

por Ji, Jiao, Yu, Yan, Li, Zhi-Ling, Chen, Ming-Yuan, Deng, Rong, Huang, Xiang, Wang, Guang-Feng, Zhang, Meng-Xia, Yang, Qi, Ravichandran, Senthilkumar, Feng, Gong-Kan, Xu, Xue-Lian, Yang, Chen-Lu, Qiu, Miao-Zhen, Jiao, Lin, Yang, Dajun, Zhu, Xiao-Feng
Publicado 2018

Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma

por Deng, Rong, Huang, Jun-Hao, Wang, Yan, Zhou, Li-Huan, Wang, Zi-Feng, Hu, Bing-Xin, Chen, Yu-Hong, Yang, Dong, Mai, Jia, Li, Zhi-Ling, Zhang, Hai-Liang, Huang, Yun, Peng, Xiao-Dan, Feng, Gong-Kan, Zhu, Xiao-Feng, Tang, Jun
Publicado 2020

Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation

por Li, Zhi-Ling, Zhang, Hai-Liang, Huang, Yun, Huang, Jun-Hao, Sun, Peng, Zhou, Ning-Ning, Chen, Yu-Hong, Mai, Jia, Wang, Yan, Yu, Yan, Zhou, Li-Huan, Li, Xuan, Yang, Dong, Peng, Xiao-Dan, Feng, Gong-Kan, Tang, Jun, Zhu, Xiao-Feng, Deng, Rong
Publicado 2020

FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer

por Huang, Yun, Zhang, Hai-Liang, Li, Zhi-Ling, Du, Tian, Chen, Yu-Hong, Wang, Yan, Ni, Huan-He, Zhang, Kai-Ming, Mai, Jia, Hu, Bing-Xin, Huang, Jun-Hao, Zhou, Li-Huan, Yang, Dong, Peng, Xiao-Dan, Feng, Gong-Kan, Tang, Jun, Zhu, Xiao-Feng, Deng, Rong
Publicado 2021