Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species

por Fennell, D A, Corbo, M, Pallaska, A, Cotter, F E
Publicado 2001

Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer

por Pallis, A G, Fennell, D A, Szutowicz, E, Leighl, N B, Greillier, L, Dziadziuszko, R
Publicado 2011

Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

por Ravindranath, A, Yuen, H-F, Chan, K-K, Grills, C, Fennell, D A, Lappin, T R, El-Tanani, M
Publicado 2011

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK

por McCoy, F, Hurwitz, J, McTavish, N, Paul, I, Barnes, C, O'Hagan, B, Odrzywol, K, Murray, J, Longley, D, McKerr, G, Fennell, D A
Publicado 2010

SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma

por Crawford, N, Stasik, I, Holohan, C, Majkut, J, McGrath, M, Johnston, P G, Chessari, G, Ward, G A, Waugh, D J, Fennell, D A, Longley, D B
Publicado 2013

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance

por Barbone, D, Ryan, J A, Kolhatkar, N, Chacko, A D, Jablons, D M, Sugarbaker, D J, Bueno, R, Letai, A G, Coussens, L M, Fennell, D A, Broaddus, V C
Publicado 2011

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer

por Paul, I, Chacko, A D, Stasik, I, Busacca, S, Crawford, N, McCoy, F, McTavish, N, Wilson, B, Barr, M, O'Byrne, K J, Longley, D B, Fennell, D A
Publicado 2012

Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo

por Manente, A G, Valenti, D, Pinton, G, Jithesh, P V, Daga, A, Rossi, L, Gray, S G, O'Byrne, K J, Fennell, D A, Vacca, R A, Nilsson, S, Mutti, L, Moro, L
Publicado 2013

Resistance to HSP90 inhibition involving loss of MCL1 addiction

por Busacca, S, Law, E W P, Powley, I R, Proia, D A, Sequeira, M, Le Quesne, J, Klabatsa, A, Edwards, J M, Matchett, K B, Luo, J L, Pringle, J H, El-Tanani, M, MacFarlane, M, Fennell, D A
Publicado 2016

Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer

por Riley, J S, Hutchinson, R, McArt, D G, Crawford, N, Holohan, C, Paul, I, Van Schaeybroeck, S, Salto-Tellez, M, Johnston, P G, Fennell, D A, Gately, K, O'Byrne, K, Cummins, R, Kay, E, Hamilton, P, Stasik, I, Longley, D B
Publicado 2013

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati...

por Lim, Eric, Darlison, Liz, Edwards, John, Elliott, Daisy, Fennell, D A, Popat, Sanjay, Rintoul, Robert C, Waller, David, Ali, Clinton, Bille, Andrea, Fuller, Liz, Ionescu, Andreea, Keni, Manjusha, Kirk, Alan, Koh, Pek, Lau, Kelvin, Mansy, Talal, Maskell, Nick A, Milton, Richard, Muthukumar, Dakshinamoorthy, Pope, Tony, Roy, Amy, Shah, Riyaz, Shamash, Jonathan, Tasigiannopoulos, Zacharias, Taylor, Paul, Treece, Sarah, Ashton, Kate, Harris, Rosie, Joyce, Katherine, Warnes, Barbara, Mills, Nicola, Stokes, Elizabeth A, Rogers, Chris
Publicado 2020

Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels

por Ramarao-Milne, P., Kondrashova, O., Patch, A.-M., Nones, K., Koufariotis, L.T., Newell, F., Addala, V., Lakis, V., Holmes, O., Leonard, C., Wood, S., Xu, Q., Mukhopadhyay, P., Naeini, M.M., Steinfort, D., Williamson, J.P., Bint, M., Pahoff, C., Nguyen, P.T., Twaddell, S., Arnold, D., Grainge, C., Basirzadeh, F., Fielding, D., Dalley, A.J., Chittoory, H., Simpson, P.T., Aoude, L.G., Bonazzi, V.F., Patel, K., Barbour, A.P., Fennell, D.A., Robinson, B.W., Creaney, J., Hollway, G., Pearson, J.V., Waddell, N.
Publicado 2022