Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer

por Fennell, Dean A, Swanton, Charles
Publicado 2012

Circumventing HSP90 inhibitors via apoptosis block

por Fennell, Dean A., Busacca, Sara
Publicado 2015

Mesothelioma: Hippo pathway as a target, lessons from COMMAND

por Fennell, Dean A., Baitei, Essa Y.
Publicado 2019

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

por Chacko, Alex D, Liberante, Fabio, Paul, Ian, Longley, Daniel B, Fennell, Dean A
Publicado 2010

Gene Expression Meta-Analysis Identifies VDAC1 as a Predictor of Poor Outcome in Early Stage Non-Small Cell Lung Cancer

por Grills, Claire, Jithesh, Puthen V., Blayney, Jaine, Zhang, Shu-Dong, Fennell, Dean A.
Publicado 2011

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs

por Bayliss, Richard, Choi, Jene, Fennell, Dean A., Fry, Andrew M., Richards, Mark W.
Publicado 2016

Dynamical Systems Analysis of Mitochondrial BAK Activation Kinetics Predicts Resistance to BH3 Domains

por Grills, Claire, Crawford, Nyree, Chacko, Alex, Johnston, Patrick G., O'Rourke, Francesca, Fennell, Dean A.
Publicado 2008

Ultra-Fast Processing of Gigapixel Tissue MicroArray Images Using High Performance Computing

por Wang, Yinhai, McCleary, David, Wang, Ching-Wei, Kelly, Paul, James, Jackie, Fennell, Dean A., Hamilton, Peter
Publicado 2010

A TMA De-Arraying Method for High Throughput Biomarker Discovery in Tissue Research

por Wang, Yinhai, Savage, Kienan, Grills, Claire, McCavigan, Andrena, James, Jacqueline A., Fennell, Dean A., Hamilton, Peter W.
Publicado 2011

CDKN2A Determines Mesothelioma Cell Fate to EZH2 Inhibition

por Pinton, Giulia, Wang, Zhuo, Balzano, Cecilia, Missaglia, Sara, Tavian, Daniela, Boldorini, Renzo, Fennell, Dean A., Griffin, Martin, Moro, Laura
Publicado 2021

Corrigendum: CDKN2A determines mesothelioma cell fate to EZH2 inhibition

por Pinton, Giulia, Wang, Zhuo, Balzano, Cecilia, Missaglia, Sara, Tavian, Daniela, Boldorini, Renzo, Fennell, Dean A., Griffin, Martin, Moro, Laura
Publicado 2022

The deubiquitinating enzyme USP17 is associated with nonsmall cell lung cancer (NSCLC) recurrence and metastasis

por McFarlane, Cheryl, McFarlane, Suzanne, Paul, Ian, Arthur, Kenneth, Scheaff, Michael, Kerr, Keith, Stevenson, Michael, Fennell, Dean A., Johnston, James A.
Publicado 2013

Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): A multicentre, randomised, controlled, phase 2 trial

por Fennell, Dean A., Porter, Catharine, Lester, Jason, Danson, Sarah, Blackhall, Fiona, Nicolson, Marianne, Nixon, Lisette, Gardner, Georgina, White, Ann, Griffiths, Gareth, Casbard, Angela
Publicado 2022

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

por Barbone, Dario, Van Dam, Loes, Follo, Carlo, Jithesh, Puthen V., Zhang, Shu-Dong, Richards, William G., Bueno, Raphael, Fennell, Dean A., Broaddus, V. Courtney
Publicado 2016

Vorinostat Eliminates Multicellular Resistance of Mesothelioma 3D Spheroids via Restoration of Noxa Expression

por Barbone, Dario, Cheung, Priscilla, Battula, Sailaja, Busacca, Sara, Gray, Steven G., Longley, Daniel B., Bueno, Raphael, Sugarbaker, David J., Fennell, Dean A., Broaddus, V. Courtney
Publicado 2012

BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms

por Singh, Anita, Busacca, Sara, Gaba, Aarti, Sheaff, Michael, Poile, Charlotte, Nakas, Apostolos, Dzialo, Joanna, Bzura, Aleksandra, Dawson, Alan G., Fennell, Dean A., Fry, Andrew M.
Publicado 2022

Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Resul...

por Fennell, Dean A., Myrand, Scott P., Nguyen, Tuan S., Ferry, David, Kerr, Keith M., Maxwell, Perry, Moore, Stephen D., Visseren-Grul, Carla, Das, Mayukh, Nicolson, Marianne C.
Publicado 2014

Inclusion of multiple high‐risk histopathological criteria improves the prediction of adjuvant chemotherapy efficacy in lung adenocarcinoma

por Sereno, Marco, He, Zhangyi, Smith, Claire R, Baena, Juvenal, Das, Madhumita, Hastings, Robert K, Rake, Grace, Fennell, Dean A, Nakas, Apostolos, Moore, David A, Le Quesne, John
Publicado 2021

BAK and NOXA Are Critical Determinants of Mitochondrial Apoptosis Induced by Bortezomib in Mesothelioma

por Busacca, Sara, Chacko, Alex D., Klabatsa, Astero, Arthur, Kenneth, Sheaff, Michael, Gunasekharan, Vignesh K., Gorski, Julia J., El-Tanani, Mohamed, Broaddus, V. Courtney, Gaudino, Giovanni, Fennell, Dean A.
Publicado 2013

Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature

por Barr, Martin P., Gray, Steven G., Hoffmann, Andreas C., Hilger, Ralf A., Thomale, Juergen, O’Flaherty, John D., Fennell, Dean A., Richard, Derek, O’Leary, John J., O’Byrne, Kenneth J.
Publicado 2013