Exploring the Interface between Inflammatory and Therapeutic Glucocorticoid Induced Bone and Muscle Loss

por Webster, Justine M., Fenton, Chloe G., Langen, Ramon, Hardy, Rowan S.
Publicado 2019

OR09-3 11β-HSD1 Mediates a Partial Suppression of Muscle Atrophy in Chronic Inflammatory Disease in Response to Therapeutic Glucocorticoids

por Webster, Justine, Fenton, Chloe, Raza, Karim, Lavery, Gareth, Langen, Ramon, Hardy, Rowan
Publicado 2019

SAT-003 Therapeutic Glucocorticoids Prevent Local and Systemic Bone Loss but Exacerbate Muscle Wasting When Administered in Chronic Inflammation

por Fenton, Chloe, Webster, Justine, Fareed, Syeda, Martin, Claire, Wehmeyer, Corinna, Cooper, Mark, Buckley, Chris, Lavery, Gareth, Langen, Ramon, Raza, Karim, Hardy, Rowan
Publicado 2019

Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids

por Fenton, Chloe, Martin, Claire, Jones, Rachel, Croft, Adam, Campos, Joana, Naylor, Amy J, Taylor, Angela E, Chimen, Myriam, Cooper, Mark, Lavery, Gareth G, Raza, Karim, Hardy, Rowan S
Publicado 2021

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

por Webster, Justine M., Sagmeister, Michael S., Fenton, Chloe G., Seabright, Alex P., Lai, Yu-Chiang, Jones, Simon W., Filer, Andrew, Cooper, Mark S., Lavery, Gareth G., Raza, Karim, Langen, Ramon, Hardy, Rowan S.
Publicado 2021

Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks

por Ugur, Milas, Labios, R. Jacob, Fenton, Chloe, Knöpper, Konrad, Jobin, Katarzyna, Imdahl, Fabian, Golda, Gosia, Hoh, Kathrin, Grafen, Anika, Kaisho, Tsuneyasu, Saliba, Antoine-Emmanuel, Grün, Dominic, Gasteiger, Georg, Bajénoff, Marc, Kastenmüller, Wolfgang
Publicado 2023

11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation

por Fenton, Chloe G, Crastin, Ana, Martin, Claire S, Suresh, Saicharan, Montagna, Isabella, Hussain, Bismah, Naylor, Amy J, Jones, Simon W, Hansen, Morten S, Gorvin, Caroline M, Price, Maria, Filer, Andrew, Cooper, Mark S, Lavery, Gareth G, Raza, Karim, Hardy, Rowan S
Publicado 2022