Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NF-κB Signalling

por Amyot, Julie, Semache, Meriem, Ferdaoussi, Mourad, Fontés, Ghislaine, Poitout, Vincent
Publicado 2012

A role for PKD1 in insulin secretion downstream of P2Y(1) receptor activation in mouse and human islets

por Khan, Shara, Ferdaoussi, Mourad, Bautista, Austin, Bergeron, Valérie, Smith, Nancy, Poitout, Vincent, MacDonald, Patrick E.
Publicado 2019

SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells

por Ferdaoussi, Mourad, Fu, Jianyang, Dai, Xiaoqing, Manning Fox, Jocelyn E., Suzuki, Kunimasa, Smith, Nancy, Plummer, Gregory, MacDonald, Patrick E.
Publicado 2017

Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity

por Brajkovic, Saška, Ferdaoussi, Mourad, Pawlowski, Valérie, Ezanno, Hélène, Plaisance, Valérie, Zmuda, Erik, Hai, Tsonwin, Annicotte, Jean-Sébastien, Waeber, Gérard, Abderrahmani, Amar
Publicado 2016

PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets

por Kolic, Jelena, Manning Fox, Jocelyn E., Chepurny, Oleg G., Spigelman, Aliya F., Ferdaoussi, Mourad, Schwede, Frank, Holz, George G., MacDonald, Patrick E.
Publicado 2016

Improved glucose tolerance with DPPIV inhibition requires β‐cell SENP1 amplification of glucose‐stimulated insulin secretion

por Ferdaoussi, Mourad, Smith, Nancy, Lin, Haopeng, Bautista, Austin, Spigelman, Aliya F., Lyon, James, Dai, XiaoQing, Manning Fox, Jocelyn E., MacDonald, Patrick E.
Publicado 2020

Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart

por Takahara, Shingo, Soni, Shubham, Phaterpekar, Kiran, Kim, Ty T., Maayah, Zaid H., Levasseur, Jody L., Silver, Heidi L., Freed, Darren H., Ferdaoussi, Mourad, Dyck, Jason R.B.
Publicado 2021

Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

por Maayah, Zaid H., Takahara, Shingo, Alam, Abrar S., Ferdaoussi, Mourad, Sutendra, Gopinath, El-Kadi, Ayman O. S., Mackey, John R., Pituskin, Edith, Paterson, D. Ian, Dyck, Jason R. B.
Publicado 2020

Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling

por Maayah, Zaid H., Ferdaoussi, Mourad, Boukouris, Aristeidis E., Takahara, Shingo, Das, Subhash K., Khairy, Mostafa, Mackey, John R., Pituskin, Edith, Sutendra, Gopinath, Paterson, D. Ian, Dyck, Jason R.B.
Publicado 2023

Metabolomic Fingerprint of Behavioral Changes in Response to Full-Spectrum Cannabis Extracts

por Maayah, Zaid H., Raposo, Pamela J. F., Silver, Heidi, Mandal, Rupasri, Ellis, Lee, Alam, Abrar S., Takahara, Shingo, Ferdaoussi, Mourad, Mathewson, Kyle E., Eurich, Dean T., Fouad, Karim, Wishart, David S., Dyck, Jason R. B.
Publicado 2022

β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet–Fed Mice

por Lin, Haopeng, Smith, Nancy, Spigelman, Aliya F., Suzuki, Kunimasa, Ferdaoussi, Mourad, Alghamdi, Tamadher A., Lewandowski, Sophie L., Jin, Yaxing, Bautista, Austin, Wang, Ying Wayne, Manning Fox, Jocelyn E., Merrins, Matthew J., Buteau, Jean, MacDonald, Patrick E.
Publicado 2021

Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

por Alghamdi, Tamadher A., Krentz, Nicole A.J., Smith, Nancy, Spigelman, Aliya F., Rajesh, Varsha, Jha, Alokkumar, Ferdaoussi, Mourad, Suzuki, Kunimasa, Yang, Jing, Manning Fox, Jocelyn E., Sun, Han, Sun, Zijie, Gloyn, Anna L., MacDonald, Patrick E.
Publicado 2022