Cytokine absorption during human kidney perfusion reduces delayed graft function–associated inflammatory gene signature

por Ferdinand, John R., Hosgood, Sarah A., Moore, Tom, Ferro, Ashley, Ward, Christopher J., Castro‐Dopico, Tomas, Nicholson, Michael L., Clatworthy, Menna R.
Publicado 2020

Bromodomain Inhibitors Modulate FcγR-Mediated Mononuclear Phagocyte Activation and Chemotaxis

por Banham, Gemma D., Lee, Colin Y. C., Ferdinand, John R., Matthews, Rebeccah J., Jing, Chenzhi, Smithers, Nicholas, Prinjha, Rab K., Clatworthy, Menna R.
Publicado 2022

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes

por Benson, Robert A., Garcon, Fabien, Recino, Asha, Ferdinand, John R., Clatworthy, Menna R., Waldmann, Herman, Brewer, James M., Okkenhaug, Klaus, Cooke, Anne, Garside, Paul, Wållberg, Maja
Publicado 2018

Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis

por Richoz, Nathan, Tuong, Zewen K., Loudon, Kevin W., Patiño-Martínez, Eduardo, Ferdinand, John R., Portet, Anaïs, Bashant, Kathleen R., Thevenon, Emeline, Rucci, Francesca, Hoyler, Thomas, Junt, Tobias, Kaplan, Mariana J., Siegel, Richard M., Clatworthy, Menna R.
Publicado 2023

Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis

por Richoz, Nathan, Tuong, Zewen K., Loudon, Kevin W., Patiño-Martínez, Eduardo, Ferdinand, John R., Portet, Anaïs, Bashant, Kathleen R., Thevenon, Emeline, Rucci, Francesca, Hoyler, Thomas, Junt, Tobias, Kaplan, Mariana J., Siegel, Richard M., Clatworthy, Menna R.
Publicado 2022

GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation

por Castro-Dopico, Tomas, Fleming, Aaron, Dennison, Thomas W., Ferdinand, John R., Harcourt, Katherine, Stewart, Benjamin J., Cader, Zaeem, Tuong, Zewen K., Jing, Chenzhi, Lok, Laurence S.C., Mathews, Rebeccah J., Portet, Anaïs, Kaser, Arthur, Clare, Simon, Clatworthy, Menna R.
Publicado 2020

Tissue-resident B cells orchestrate macrophage polarisation and function

por Suchanek, Ondrej, Ferdinand, John R., Tuong, Zewen K., Wijeyesinghe, Sathi, Chandra, Anita, Clauder, Ann-Katrin, Almeida, Larissa N., Clare, Simon, Harcourt, Katherine, Ward, Christopher J., Bashford-Rogers, Rachael, Lawley, Trevor, Manz, Rudolf A., Okkenhaug, Klaus, Masopust, David, Clatworthy, Menna R.
Publicado 2023

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

por Tuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E., Frazer, Ian H.
Publicado 2021

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis

por Castro-Dopico, Tomas, Dennison, Thomas W., Ferdinand, John R., Mathews, Rebeccah J., Fleming, Aaron, Clift, Dean, Stewart, Benjamin J., Jing, Chenzhi, Strongili, Konstantina, Labzin, Larisa I., Monk, Edward J.M., Saeb-Parsy, Kourosh, Bryant, Clare E., Clare, Simon, Parkes, Miles, Clatworthy, Menna R.
Publicado 2019

In vivo labeling reveals continuous trafficking of TCF-1(+) T cells between tumor and lymphoid tissue

por Li, Zhi, Tuong, Zewen K., Dean, Isaac, Willis, Claire, Gaspal, Fabrina, Fiancette, Rémi, Idris, Suaad, Kennedy, Bethany, Ferdinand, John R., Peñalver, Ana, Cabantous, Mia, Murtuza Baker, Syed, Fry, Jeremy W., Carlesso, Gianluca, Hammond, Scott A., Dovedi, Simon J., Hepworth, Matthew R., Clatworthy, Menna R., Withers, David R.
Publicado 2022

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis

por Jing, Chenzhi, Castro-Dopico, Tomas, Richoz, Nathan, Tuong, Zewen K., Ferdinand, John R., Lok, Laurence S. C., Loudon, Kevin W., Banham, Gemma D., Mathews, Rebeccah J., Cader, Zaeem, Fitzpatrick, Susan, Bashant, Kathleen R., Kaplan, Mariana J., Kaser, Arthur, Johnson, Randall S., Murphy, Michael P., Siegel, Richard M., Clatworthy, Menna R.
Publicado 2020

Ageing is associated with maladaptive immune response and worse outcome after traumatic brain injury

por Moro, Federico, Pischiutta, Francesca, Portet, Anaïs, Needham, Edward J., Norton, Emma J., Ferdinand, John R., Vegliante, Gloria, Sammali, Eliana, Pascente, Rosaria, Caruso, Enrico, Micotti, Edoardo, Tolomeo, Daniele, di Marco Barros, Rafael, Fraunberger, Erik, Wang, Kevin K. W., Esser, Michael J., Menon, David K., Clatworthy, Menna R., Zanier, Elisa R.
Publicado 2022

Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence

por Riding, Alexandra M., Loudon, Kevin W., Guo, Andrew, Ferdinand, John R., Lok, Laurence S.C., Richoz, Nathan, Stewart, Andrew, Castro-Dopico, Tomas, Tuong, Zewen Kelvin, Fiancette, Remi, Bowyer, Georgina S., Fleming, Aaron, Gillman, Eleanor S., Suchanek, Ondrej, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Withers, David, Dougan, Gordan, Clare, Simon, Clatworthy, Menna R.
Publicado 2022

HIF1A and NFAT5 coordinate Na(+)-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting

por Neubert, Patrick, Weichselbaum, Andrea, Reitinger, Carmen, Schatz, Valentin, Schröder, Agnes, Ferdinand, John R., Simon, Michaela, Bär, Anna-Lorena, Brochhausen, Christoph, Gerlach, Roman G., Tomiuk, Stefan, Hammer, Karin, Wagner, Stefan, van Zandbergen, Ger, Binger, Katrina J., Müller, Dominik N., Kitada, Kento, Clatworthy, Menna R., Kurts, Christian, Titze, Jens, Abdullah, Zeinab, Jantsch, Jonathan
Publicado 2019

Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo

por Booty, Lee M., Gawel, Justyna M., Cvetko, Filip, Caldwell, Stuart T., Hall, Andrew R., Mulvey, John F., James, Andrew M., Hinchy, Elizabeth C., Prime, Tracy A., Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P., Clatworthy, Menna R., Ferdinand, John R., Prag, Hiran A., Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Publicado 2019

Heat inactivation of clinical COVID-19 samples on an industrial scale for low risk and efficient high-throughput qRT-PCR diagnostic testing

por Delpuech, Oona, Douthwaite, Julie A., Hill, Thomas, Niranjan, Dhevahi, Malintan, Nancy T., Duvoisin, Hannah, Elliott, Jane, Goodfellow, Ian, Hosmillo, Myra, Orton, Alexandra L., Taylor, Molly A., Brankin, Christopher, Pitt, Haidee, Ross-Thriepland, Douglas, Siek, Magdalena, Cuthbert, Anna, Richards, Ian, Ferdinand, John R., Barker, Colin, Shaw, Robert, Ariani, Cristina, Waddell, Ian, Rees, Steve, Green, Clive, Clark, Roger, Upadhyay, Abhishek, Howes, Rob
Publicado 2022

Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

por Zhang, Yang, Garcia-Ibanez, Laura, Ulbricht, Carolin, Lok, Laurence S. C., Pike, Jeremy A., Mueller-Winkler, Jennifer, Dennison, Thomas W., Ferdinand, John R., Burnett, Cameron J. M., Yam-Puc, Juan C., Zhang, Lingling, Alfaro, Raul Maqueda, Takahama, Yousuke, Ohigashi, Izumi, Brown, Geoffrey, Kurosaki, Tomohiro, Tybulewicz, Victor L. J., Rot, Antal, Hauser, Anja E., Clatworthy, Menna R., Toellner, Kai-Michael
Publicado 2022

Distinct microbial and immune niches of the human colon

por James, Kylie R, Gomes, Tomas, Elmentaite, Rasa, Kumar, Nitin, Gulliver, Emily L, King, Hamish W, Stares, Mark D, Bareham, Bethany R, Ferdinand, John R, Petrova, Velislava N, Polański, Krzysztof, Forster, Samuel C, Jarvis, Lorna B, Suchanek, Ondrej, Howlett, Sarah, James, Louisa K, Jones, Joanne L, Meyer, Kerstin B, Clatworthy, Menna R, Saeb-Parsy, Kourosh, Lawley, Trevor D, Teichmann, Sarah A
Publicado 2020

Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids

por Rimland, Casey A., Tilson, Samantha G., Morell, Carola M., Tomaz, Rute A., Lu, Wei‐Yu, Adams, Simone E., Georgakopoulos, Nikitas, Otaizo‐Carrasquero, Francisco, Myers, Timothy G., Ferdinand, John R., Gieseck, Richard L., Sampaziotis, Fotios, Tysoe, Olivia C., Ross, Alexander, Kraiczy, Judith M., Wesley, Brandon, Muraro, Daniele, Zilbauer, Matthias, Oniscu, Gabriel C., Hannan, Nicholas R.F., Forbes, Stuart J., Saeb‐Parsy, Kourosh, Wynn, Thomas A., Vallier, Ludovic
Publicado 2021

Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer

por Li, Ruoyan, Ferdinand, John R., Loudon, Kevin W., Bowyer, Georgina S., Laidlaw, Sean, Muyas, Francesc, Mamanova, Lira, Neves, Joana B., Bolt, Liam, Fasouli, Eirini S., Lawson, Andrew R.J., Young, Matthew D., Hooks, Yvette, Oliver, Thomas R.W., Butler, Timothy M., Armitage, James N., Aho, Tev, Riddick, Antony C.P., Gnanapragasam, Vincent, Welsh, Sarah J., Meyer, Kerstin B., Warren, Anne Y., Tran, Maxine G.B., Stewart, Grant D., Cortés-Ciriano, Isidro, Behjati, Sam, Clatworthy, Menna R., Campbell, Peter J., Teichmann, Sarah A., Mitchell, Thomas J.
Publicado 2022