Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog

por Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella, Jacob, Gary S
Publicado 2017

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

por Padalino, Gilda, Ferla, Salvatore, Brancale, Andrea, Chalmers, Iain W., Hoffmann, Karl F.
Publicado 2018

Erratum to ‘Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni’ [IJP Drugs...

por Padalino, Gilda, Ferla, Salvatore, Brancale, Andrea, Chalmers, Iain W., Hoffmann, Karl F.
Publicado 2019

Handheld Raman Spectroscopy in the First UK Home Office Licensed Pharmacist-Led Community Drug Checking Service

por Mullin, Anthony, Scott, Mark, Vaccaro, Giorgia, Gittins, Rosalind, Ferla, Salvatore, Schifano, Fabrizio, Guirguis, Amira
Publicado 2023

Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents

por Bassetto, Marcella, Ferla, Salvatore, Giancotti, Gilda, Pertusati, Fabrizio, Westwell, Andrew D., Brancale, Andrea, McGuigan, Christopher
Publicado 2017

A Composite System Based upon Hydroxypropyl Cyclodextrins and Soft Hydrogel Contact Lenses for the Delivery of Therapeutic Doses of Econazole to the Cornea, In Vitro

por Wong, Anepmete, Fallon, Melissa, Celiksoy, Vildan, Ferla, Salvatore, Varricchio, Carmine, Whitaker, David, Quantock, Andrew J., Heard, Charles M.
Publicado 2022

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replicat...

por Płaszczyca, Anna, Scaturro, Pietro, Neufeldt, Christopher John, Cortese, Mirko, Cerikan, Berati, Ferla, Salvatore, Brancale, Andrea, Pichlmair, Andreas, Bartenschlager, Ralf
Publicado 2019

A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase

por Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T., Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella
Publicado 2019

Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections

por Flude, Ben M., Nannetti, Giulio, Mitchell, Paige, Compton, Nina, Richards, Chloe, Heurich, Meike, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella
Publicado 2021

Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts

por Xiang, Haoyue, Ferla, Salvatore, Varricchio, Carmine, Brancale, Andrea, Brown, Nicola L., Black, Gary W., Turner, Nicholas J., Castagnolo, Daniele
Publicado 2023

In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase

por Ferla, Salvatore, Netzler, Natalie E., Ferla, Sebastiano, Veronese, Sofia, Tuipulotu, Daniel Enosi, Guccione, Salvatore, Brancale, Andrea, White, Peter A., Bassetto, Marcella
Publicado 2018

Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents

por Oliva, Paola, Onnis, Valentina, Balboni, Elisa, Hamel, Ernest, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francisco, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Romagnoli, Romeo
Publicado 2020

Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins

por Pasqualetto, Gaia, Schepelmann, Martin, Varricchio, Carmine, Pileggi, Elisa, Khogali, Caroline, Morgan, Siân R., Boostrom, Ian, Rozanowska, Malgorzata, Brancale, Andrea, Ferla, Salvatore, Bassetto, Marcella
Publicado 2020

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

por Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Cacciari, Barbara, Balzarini, Jan, Liekens, Sandra, Hamel, Ernest, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Zurlo, Matteo, Finotti, Alessia, Gambari, Roberto
Publicado 2020

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets

por Whatley, Kezia C. L., Padalino, Gilda, Whiteland, Helen, Geyer, Kathrin K., Hulme, Benjamin J., Chalmers, Iain W., Forde-Thomas, Josephine, Ferla, Salvatore, Brancale, Andrea, Hoffmann, Karl F.
Publicado 2019

Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

por Albulescu, Irina C., White-Scholten, Leonie, Tas, Ali, Hoornweg, Tabitha E., Ferla, Salvatore, Kovacikova, Kristina, Smit, Jolanda M., Brancale, Andrea, Snijder, Eric J., van Hemert, Martijn J.
Publicado 2020

Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

por Oliva, Paola, Romagnoli, Romeo, Cacciari, Barbara, Manfredini, Stefano, Padroni, Chiara, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Corallo, Diana, Aveic, Sanja, Milan, Noemi, Mariotto, Elena, Viola, Giampietro, Bortolozzi, Roberta
Publicado 2022

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

por Romagnoli, Romeo, Oliva, Paola, Prencipe, Filippo, Manfredini, Stefano, Budassi, Federica, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Corallo, Diana, Aveic, Sanja, Manfreda, Lorenzo, Mariotto, Elena, Bortolozzi, Roberta, Viola, Giampietro
Publicado 2022

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole

por Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Tabrizi, Mojgan Aghazadeh, Lopez-Cara, Luisa Carlota, Ferla, Salvatore, Brancale, Andrea, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Basso, Giuseppe, Viola, Giampietro
Publicado 2016

Structure–Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections

por Ferla, Salvatore, Varricchio, Carmine, Knight, William, Ho, Pui Kei, Saporito, Fabiana, Tropea, Beatrice, Fagan, Giulio, Flude, Ben Matthew, Bevilacqua, Federica, Santos-Ferreira, Nanci, Van Dycke, Jana, Neyts, Johan, Brancale, Andrea, Rocha-Pereira, Joana, Bassetto, Marcella
Publicado 2021