Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism

por Fernández-Borges, Natalia, Eraña, Hasier, Elezgarai, Saioa R., Harrathi, Chafik, Gayosso, Mayela, Castilla, Joaquín
Publicado 2013

Detection of PrPres in Genetically Susceptible Fetuses from Sheep with Natural Scrapie

por Garza, María Carmen, Fernández-Borges, Natalia, Bolea, Rosa, Badiola, Juan José, Castilla, Joaquín, Monleón, Eva
Publicado 2011

Insights into the Bidirectional Properties of the Sheep–Deer Prion Transmission Barrier

por Harrathi, Chafik, Fernández-Borges, Natalia, Eraña, Hasier, Elezgarai, Saioa R., Venegas, Vanessa, Charco, Jorge M., Castilla, Joaquín
Publicado 2018

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease

por Otero, Alicia, Betancor, Marina, Eraña, Hasier, Fernández Borges, Natalia, Lucas, José J., Badiola, Juan José, Castilla, Joaquín, Bolea, Rosa
Publicado 2021

Ultra-Efficient PrP(Sc) Amplification Highlights Potentialities and Pitfalls of PMCA Technology

por Cosseddu, Gian Mario, Nonno, Romolo, Vaccari, Gabriele, Bucalossi, Cecilia, Fernandez-Borges, Natalia, Di Bari, Michele Angelo, Castilla, Joaquin, Agrimi, Umberto
Publicado 2011

Canine D(163)-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context

por Marín-Moreno, Alba, Espinosa, Juan Carlos, Aguilar-Calvo, Patricia, Fernández-Borges, Natalia, Pitarch, José Luis, González, Lorenzo, Torres, Juan María
Publicado 2021

Prion-resistant or prion-susceptible species, this is the question

por Chianini, Francesca, Fernández-Borges, Natalia, Eraña, Hasier, Pang, Yvonne, Vidal, Enric, Eaton, Samantha L., Finlayson, Jeanie, Dagleish, Mark P., Castilla, Joaquín
Publicado 2013

Protective Effect of Val(129)-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease

por Fernández-Borges, Natalia, Espinosa, Juan Carlos, Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Asante, Emmanuel A., Kitamoto, Tetsuyuki, Mohri, Shirou, Andréoletti, Olivier, Torres, Juan María
Publicado 2017

Unraveling the key to the resistance of canids to prion diseases

por Fernández-Borges, Natalia, Parra, Beatriz, Vidal, Enric, Eraña, Hasier, Sánchez-Martín, Manuel A., de Castro, Jorge, Elezgarai, Saioa R., Pumarola, Martí, Mayoral, Tomás, Castilla, Joaquín
Publicado 2017

Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome

por Elezgarai, Saioa R., Fernández-Borges, Natalia, Eraña, Hasier, Sevillano, Alejandro M., Charco, Jorge M., Harrathi, Chafik, Saá, Paula, Gil, David, Kong, Qingzhong, Requena, Jesús R., Andréoletti, Olivier, Castilla, Joaquín
Publicado 2017

Classical scrapie in small ruminants is caused by at least four different prion strains

por Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Espinosa, Juan Carlos, Zamora-Ceballos, María, Pitarch, José Luis, González, Lorenzo, Fernández-Borges, Natalia, Orge, Leonor, Andréoletti, Olivier, Nonno, Romolo, Torres, Juan María
Publicado 2021

Transgenic Mouse Bioassay: Evidence That Rabbits Are Susceptible to a Variety of Prion Isolates

por Vidal, Enric, Fernández-Borges, Natalia, Pintado, Belén, Eraña, Hasier, Ordóñez, Montserrat, Márquez, Mercedes, Chianini, Francesca, Fondevila, Dolors, Sánchez-Martín, Manuel A., Andreoletti, Olivier, Dagleish, Mark P., Pumarola, Martí, Castilla, Joaquín
Publicado 2015

Susceptibility of European Red Deer (Cervus elaphus elaphus) to Alimentary Challenge with Bovine Spongiform Encephalopathy

por Dagleish, Mark P., Martin, Stuart, Steele, Philip, Finlayson, Jeanie, Eaton, Samantha L., Sisó, Sílvia, Stewart, Paula, Fernández-Borges, Natalia, Hamilton, Scott, Pang, Yvonne, Chianini, Francesca, Reid, Hugh W., Goldmann, Wilfred, González, Lorenzo, Castilla, Joaquín, Jeffrey, Martin
Publicado 2015

Transgenic Fatal Familial Insomnia Mice Indicate Prion Infectivity-Independent Mechanisms of Pathogenesis and Phenotypic Expression of Disease

por Bouybayoune, Ihssane, Mantovani, Susanna, Del Gallo, Federico, Bertani, Ilaria, Restelli, Elena, Comerio, Liliana, Tapella, Laura, Baracchi, Francesca, Fernández-Borges, Natalia, Mangieri, Michela, Bisighini, Cinzia, Beznoussenko, Galina V., Paladini, Alessandra, Balducci, Claudia, Micotti, Edoardo, Forloni, Gianluigi, Castilla, Joaquín, Fiordaliso, Fabio, Tagliavini, Fabrizio, Imeri, Luca, Chiesa, Roberto
Publicado 2015

Altered Ca(2+) homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease

por Llorens, Franc, Thüne, Katrin, Sikorska, Beata, Schmitz, Matthias, Tahir, Waqas, Fernández-Borges, Natalia, Cramm, Maria, Gotzmann, Nadine, Carmona, Margarita, Streichenberger, Nathalie, Michel, Uwe, Zafar, Saima, Schuetz, Anna-Lena, Rajput, Ashish, Andréoletti, Olivier, Bonn, Stefan, Fischer, Andre, Liberski, Pawel P., Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga
Publicado 2017

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis

por Llorens, Franc, Thüne, Katrin, Martí, Eulàlia, Kanata, Eirini, Dafou, Dimitra, Díaz-Lucena, Daniela, Vivancos, Ana, Shomroni, Orr, Zafar, Saima, Schmitz, Matthias, Michel, Uwe, Fernández-Borges, Natalia, Andréoletti, Olivier, del Río, José Antonio, Díez, Juana, Fischer, Andre, Bonn, Stefan, Sklaviadis, Theodoros, Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga
Publicado 2018

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis

por Sevillano, Alejandro M., Fernández-Borges, Natalia, Younas, Neelam, Wang, Fei, R. Elezgarai, Saioa, Bravo, Susana, Vázquez-Fernández, Ester, Rosa, Isaac, Eraña, Hasier, Gil, David, Veiga, Sonia, Vidal, Enric, Erickson-Beltran, Melissa L., Guitián, Esteban, Silva, Christopher J., Nonno, Romolo, Ma, Jiyan, Castilla, Joaquín, R. Requena, Jesús
Publicado 2018

iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology

por Matamoros-Angles, Andreu, Gayosso, Lucía Mayela, Richaud-Patin, Yvonne, di Domenico, Angelique, Vergara, Cristina, Hervera, Arnau, Sousa, Amaya, Fernández-Borges, Natalia, Consiglio, Antonella, Gavín, Rosalina, López de Maturana, Rakel, Ferrer, Isidro, López de Munain, Adolfo, Raya, Ángel, Castilla, Joaquín, Sánchez-Pernaute, Rosario, del Río, José Antonio
Publicado 2017

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

por Llorens, Franc, Thüne, Katrin, Tahir, Waqas, Kanata, Eirini, Diaz-Lucena, Daniela, Xanthopoulos, Konstantinos, Kovatsi, Eleni, Pleschka, Catharina, Garcia-Esparcia, Paula, Schmitz, Matthias, Ozbay, Duru, Correia, Susana, Correia, Ângela, Milosevic, Ira, Andréoletti, Olivier, Fernández-Borges, Natalia, Vorberg, Ina M., Glatzel, Markus, Sklaviadis, Theodoros, Torres, Juan Maria, Krasemann, Susanne, Sánchez-Valle, Raquel, Ferrer, Isidro, Zerr, Inga
Publicado 2017

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies

por Eraña, Hasier, Charco, Jorge M., Di Bari, Michele A., Díaz-Domínguez, Carlos M., López-Moreno, Rafael, Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A., García-Martínez, Sandra, Bravo, Susana, Fernández-Borges, Natalia, Geijo, Mariví, D’Agostino, Claudia, Garrido, Joseba, Bian, Jifeng, König, Anna, Uluca-Yazgi, Boran, Sabate, Raimon, Khaychuk, Vadim, Vanni, Ilaria, Telling, Glenn C., Heise, Henrike, Nonno, Romolo, Requena, Jesús R., Castilla, Joaquín
Publicado 2019