The ORC/Cdc6/MCM2–7 complex, a new power player for regulated helicase loading

por Riera, Alberto, Fernández-Cid, Alejandra, Speck, Christian
Publicado 2013

Yeast importin-β is required for nuclear import of the Mig2 repressor

por Fernández-Cid, Alejandra, Vega, Montserrat, Herrero, Pilar, Moreno, Fernando
Publicado 2012

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

por Herrera, M. Carmen, Tognetti, Silvia, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Fernández-Cid, Alejandra, Speck, Christian
Publicado 2015

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

por Sun, Jingchuan, Fernandez-Cid, Alejandra, Riera, Alberto, Tognetti, Silvia, Yuan, Zuanning, Stillman, Bruce, Speck, Christian, Li, Huilin
Publicado 2014

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA

por Sun, Jingchuan, Evrin, Cecile, Samel, Stefan, Fernández-Cid, Alejandra, Riera, Alberto, Kawakami, Hironori, Stillman, Bruce, Speck, Christian, Li, Huilin
Publicado 2013

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

por Samel, Stefan A., Fernández-Cid, Alejandra, Sun, Jingchuan, Riera, Alberto, Tognetti, Silvia, Herrera, M. Carmen, Li, Huilin, Speck, Christian
Publicado 2014

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2–7 hexamer dimerization

por Evrin, Cecile, Fernández-Cid, Alejandra, Zech, Juergen, Herrera, M. Carmen, Riera, Alberto, Clarke, Pippa, Brill, Shlomo, Lurz, Rudi, Speck, Christian
Publicado 2013

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

por Evrin, Cecile, Fernández-Cid, Alejandra, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Herrera, M. Carmen, Tognetti, Silvia, Lurz, Rudi, Speck, Christian
Publicado 2014

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting

por Chalk, Rod, Greenland, William E. P., Moreira, Tiago, Coker, Jesse, Mukhopadhyay, Shubhashish M. M., Williams, Eleanor, Manning, Charlotte, Bohstedt, Tina, McCrorie, Rama, Fernandez-Cid, Alejandra, Burgess-Brown, Nicola A.
Publicado 2021

Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

por Chi, Gamma, Liang, Qiansheng, Sridhar, Akshay, Cowgill, John B., Sader, Kasim, Radjainia, Mazdak, Qian, Pu, Castro-Hartmann, Pablo, Venkaya, Shayla, Singh, Nanki Kaur, McKinley, Gavin, Fernandez-Cid, Alejandra, Mukhopadhyay, Shubhashish M. M., Burgess-Brown, Nicola A., Delemotte, Lucie, Covarrubias, Manuel, Dürr, Katharina L.
Publicado 2022

Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

por Chi, Gamma, Ebenhoch, Rebecca, Man, Henry, Tang, Haiping, Tremblay, Laurence E, Reggiano, Gabriella, Qiu, Xingyu, Bohstedt, Tina, Liko, Idlir, Almeida, Fernando G, Garneau, Alexandre P, Wang, Dong, McKinley, Gavin, Moreau, Christophe P, Bountra, Kiran D, Abrusci, Patrizia, Mukhopadhyay, Shubhashish M M, Fernandez‐Cid, Alejandra, Slimani, Samira, Lavoie, Julie L, Burgess‐Brown, Nicola A, Tehan, Ben, DiMaio, Frank, Jazayeri, Ali, Isenring, Paul, Robinson, Carol V, Dürr, Katharina L
Publicado 2021