Lead Optimization of Dehydroemetine for Repositioned Use in Malaria

por Panwar, Priyanka, Burusco, Kepa K., Abubaker, Muna, Matthews, Holly, Gutnov, Andrey, Fernández-Álvaro, Elena, Bryce, Richard A., Wilkinson, James, Nirmalan, Niroshini
Publicado 2020

Enantioselective kinetic resolution of phenylalkyl carboxylic acids using metagenome‐derived esterases

por Fernández‐Álvaro, Elena, Kourist, Robert, Winter, Julia, Böttcher, Dominique, Liebeton, Klaus, Naumer, Christian, Eck, Jürgen, Leggewie, Christian, Jaeger, Karl‐Erich, Streit, Wolfgang, Bornscheuer, Uwe T.
Publicado 2010

Tebipenem as an oral alternative for the treatment of typhoid caused by XDR Salmonella Typhi

por Mylona, Elli, Voong Vinh, Phat, Qureshi, Sonia, Karkey, Abhilasha, Dongol, Sabina, Ha Thanh, Tuyen, Walson, Judd, Ballell, Lluis, Fernández Álvaro, Elena, Qamar, Farah, Baker, Stephen
Publicado 2021

Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of Shigella flexneri

por Miljkovic, Marija, Lozano, Sonia, Castellote, Isabel, de Cózar, Cristina, Villegas-Moreno, Ana I., Gamallo, Pablo, Jimenez-Alfaro Martinez, Dolores, Fernández-Álvaro, Elena, Ballell, Lluis, Garcia, George A.
Publicado 2023

High-throughput screening of the Plasmodium falciparum cGMP-dependent protein kinase identified a thiazole scaffold which kills erythrocytic and sexual stage parasites

por Penzo, Maria, de las Heras-Dueña, Laura, Mata-Cantero, Lydia, Diaz-Hernandez, Beatriz, Vazquez-Muñiz, Maria-Jesus, Ghidelli-Disse, Sonja, Drewes, Gerard, Fernandez-Alvaro, Elena, Baker, David A.
Publicado 2019

Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development

por Fenwick, Michael K., Reers, Alexandra R., Liu, Yi, Zigweid, Rachael, Sankaran, Banumathi, Shin, Janis, Hulverson, Matthew A., Hammerson, Bradley, Fernández Álvaro, Elena, Myler, Peter J., Kaushansky, Alexis, Van Voorhis, Wesley C., Fan, Erkang, Staker, Bart L.
Publicado 2023

Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites

por Matralis, Alexios N., Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J., Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A., Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A.
Publicado 2019

The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp

por Fernández Álvaro, Elena, Voong Vinh, Phat, de Cozar, Cristina, Willé, David R, Urones, Beatriz, Cortés, Alvaro, Price, Alan, Tran Do Hoang, Nhu, Ha Thanh, Tuyen, McCloskey, Molly, Shaheen, Shareef, Dayao, Denise, Martinot, Amanda, de Mercado, Jaime, Castañeda, Pablo, García-Perez, Adolfo, Singa, Benson, Pavlinac, Patricia, Walson, Judd, Martínez-Martínez, Maria Santos, Arnold, Samuel LM, Tzipori, Saul, Ballell Pages, Lluis, Baker, Stephen
Publicado 2022

Correction: The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp

por Fernández Álvaro, Elena, Voong Vinh, Phat, de Cozar, Cristina, Willé, David R, Urones, Beatriz, Cortés, Alvaro, Price, Alan, Tran Do Hoang, Nhu, Ha Thanh, Tuyen, McCloskey, Molly, Shaheen, Shareef, Dayao, Denise, Martinot, Amanda, de Mercado, Jaime, Castañeda, Pablo, García-Perez, Adolfo, Singa, Benson, Pavlinac, Patricia, Walson, Judd, Martínez-Martínez, Maria Santos, Arnold, Samuel LM, Tzipori, Saul, Pages, Lluis Ballell, Baker, Stephen
Publicado 2022