SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology

por Morales, Lucía, Oliveros, Juan Carlos, Fernandez-Delgado, Raúl, tenOever, Benjamin Robert, Enjuanes, Luis, Sola, Isabel
Publicado 2017

Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection

por Gutiérrez-Álvarez, Javier, Honrubia, José M., Fernández-Delgado, Raúl, Wang, Li, Castaño-Rodríguez, Carlos, Zúñiga, Sonia, Sola, Isabel, Enjuanes, Luis
Publicado 2021

MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice

por Bello-Perez, Melissa, Hurtado-Tamayo, Jesús, Requena-Platek, Ricardo, Canton, Javier, Sánchez-Cordón, Pedro José, Fernandez-Delgado, Raúl, Enjuanes, Luis, Sola, Isabel
Publicado 2022

The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis

por Jimenez-Guardeño, Jose M., Nieto-Torres, Jose L., DeDiego, Marta L., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Castaño-Rodriguez, Carlos, Enjuanes, Luis
Publicado 2014

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

por Canton, Javier, Fehr, Anthony R., Fernandez-Delgado, Raúl, Gutierrez-Alvarez, Francisco J., Sanchez-Aparicio, Maria T., García-Sastre, Adolfo, Perlman, Stanley, Enjuanes, Luis, Sola, Isabel
Publicado 2018

Coronavirus virulence genes with main focus on SARS-CoV envelope gene

por DeDiego, Marta L., Nieto-Torres, Jose L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Castaño-Rodriguez, Carlos, Fernandez-Delgado, Raul, Usera, Fernando, Enjuanes, Luis
Publicado 2014

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine

por Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Nieto-Torres, Jose L., DeDiego, Marta L., Castaño-Rodriguez, Carlos, Fernandez-Delgado, Raul, Perlman, Stanley, Enjuanes, Luis
Publicado 2015

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome

por Nieto-Torres, Jose L., Verdiá-Báguena, Carmina, Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Castaño-Rodriguez, Carlos, Fernandez-Delgado, Raul, Torres, Jaume, Aguilella, Vicente M., Enjuanes, Luis
Publicado 2015

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

por Nieto-Torres, Jose L., DeDiego, Marta L., Verdiá-Báguena, Carmina, Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Castaño-Rodriguez, Carlos, Alcaraz, Antonio, Torres, Jaume, Aguilella, Vicente M., Enjuanes, Luis
Publicado 2014

Relevance of SARS-CoV E Protein Ion Channel Activity in Virus Pathogenesis

por Verdiá Báguena, Carmina, Nieto-Torres, José L., De Diego, Marta L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Castaño-Rodríguez, carlos, Torres, Jaume, Alcaraz, Antonio, Aguilella, Vicente M., Enjuanes, Luis
Publicado 2015

Forest Restoration in a Fog Oasis: Evidence Indicates Need for Cultural Awareness in Constructing the Reference

por Balaguer, Luís, Arroyo-García, Rosa, Jiménez, Percy, Jiménez, María Dolores, Villegas, Luís, Cordero, Irene, Rubio de Casas, Rafael, Fernández-Delgado, Raúl, Ron, María Eugenia, Manrique, Esteban, Vargas, Pablo, Cano, Emilio, Pueyo, José J., Aronson, James
Publicado 2011

Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

por Widjaja, Ivy, Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, van Dieren, Brenda, Okba, Nisreen M.A., Raj, V. Stalin, Li, Wentao, Fernandez-Delgado, Raul, Grosveld, Frank, van Kuppeveld, Frank J. M., Haagmans, Bart L., Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan
Publicado 2019

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis

por Castaño-Rodriguez, Carlos, Honrubia, Jose M., Gutiérrez-Álvarez, Javier, DeDiego, Marta L., Nieto-Torres, Jose L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Verdia-Báguena, Carmina, Queralt-Martín, Maria, Kochan, Grazyna, Perlman, Stanley, Aguilella, Vicente M., Sola, Isabel, Enjuanes, Luis
Publicado 2018

A One Health view of the West Nile virus outbreak in Andalusia (Spain) in 2020

por Figuerola, Jordi, Jiménez-Clavero, Miguel Ángel, Ruíz-López, María José, Llorente, Francisco, Ruiz, Santiago, Hoefer, Andreas, Aguilera-Sepúlveda, Pilar, Jiménez-Peñuela, Jéssica, García-Ruiz, Olaya, Herrero, Laura, Soriguer, Ramón C., Fernández Delgado, Raúl, Sánchez-Seco, María Paz, Martínez-de la Puente, Josué, Vázquez, Ana
Publicado 2022

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

por Stalin Raj, V., Okba, Nisreen M. A., Gutierrez-Alvarez, Javier, Drabek, Dubravka, van Dieren, Brenda, Widagdo, W., Lamers, Mart M., Widjaja, Ivy, Fernandez-Delgado, Raul, Sola, Isabel, Bensaid, Albert, Koopmans, Marion P., Segalés, Joaquim, Osterhaus, Albert D. M. E., Bosch, Berend Jan, Enjuanes, Luis, Haagmans, Bart L.
Publicado 2018

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

por Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, Li, Wentao, Okba, Nisreen M. A., Albulescu, Irina, Widjaja, Ivy, van Dieren, Brenda, Fernandez-Delgado, Raul, Sola, Isabel, Hurdiss, Daniel L., Daramola, Olalekan, Grosveld, Frank, van Kuppeveld, Frank J. M., Haagmans, Bart L., Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan
Publicado 2021

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

por Ugalde, Alejandro P, Bretones, Gabriel, Rodríguez, David, Quesada, Víctor, Llorente, Francisco, Fernández‐Delgado, Raúl, Jiménez‐Clavero, Miguel Ángel, Vázquez, Jesús, Calvo, Enrique, Tamargo‐Gómez, Isaac, Mariño, Guillermo, Roiz‐Valle, David, Maeso, Daniel, Araujo‐Voces, Miguel, Español, Yaiza, Barceló, Carles, Freije, José MP, López‐Soto, Alejandro, López‐Otín, Carlos
Publicado 2022

SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators

por Honrubia, Jose M., Gutierrez-Álvarez, Javier, Sanz-Bravo, Alejandro, González-Miranda, Ezequiel, Muñoz-Santos, Diego, Castaño-Rodriguez, Carlos, Wang, Li, Villarejo-Torres, Marta, Ripoll-Gómez, Jorge, Esteban, Ana, Fernandez-Delgado, Raul, Sánchez-Cordón, Pedro José, Oliveros, Juan Carlos, Perlman, Stanley, McCray, Paul B., Sola, Isabel, Enjuanes, Luis
Publicado 2023