Intrinsic determinants of prion protein neurotoxicity in Drosophila: from sequence to (dys)function

por Cembran, Alessandro, Fernandez-Funez, Pedro
Publicado 2023

Launching Hsp70 neuroprotection: Two drugs better than one

por Fernandez-Funez, Pedro, Rincon-Limas, Diego E
Publicado 2014

Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein

por Myers, Ryan, Cembran, Alessandro, Fernandez-Funez, Pedro
Publicado 2020

Drosophila Models of Proteinopathies: the Little Fly that Could

por Rincon-Limas, Diego E, Jensen, Kurt, Fernandez-Funez, Pedro
Publicado 2012

Visualization of synaptic domains in the Drosophila brain by magnetic resonance microscopy at 10 micron isotropic resolution

por Lee, Choong H., Blackband, Stephen J., Fernandez-Funez, Pedro
Publicado 2015

Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer’s disease

por Martin-Peña, Alfonso, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Publicado 2017

Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer’s disease

por Martín-Peña, Alfonso, Rincón-Limas, Diego E., Fernandez-Fúnez, Pedro
Publicado 2018

FoxK mediates TGF-β signalling during midgut differentiation in flies

por Casas-Tinto, Sergio, Gomez-Velazquez, Melisa, Granadino, Begoña, Fernandez-Funez, Pedro
Publicado 2008

Combined Pharmacological Induction of Hsp70 Suppresses Prion Protein Neurotoxicity in Drosophila

por Zhang, Yan, Casas-Tinto, Sergio, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Publicado 2014

secHsp70 as a tool to approach amyloid-β42 and other extracellular amyloids

por De Mena, Lorena, Chhangani, Deepak, Fernandez-Funez, Pedro, Rincon-Limas, Diego E.
Publicado 2017

Y225A induces long-range conformational changes in human prion protein that are protective in Drosophila

por Myers, Ryan R., John, Aliciarose, Zhang, Weiguanliu, Zou, Wen-Quan, Cembran, Alessandro, Fernandez-Funez, Pedro
Publicado 2023

New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion protein

por Myers, Ryan R., Sanchez-Garcia, Jonatan, Leving, Daniel C., Melvin, Richard G., Fernandez-Funez, Pedro
Publicado 2022

Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies

por Castillo-Carranza, Diana L., Zhang, Yan, Guerrero-Muñoz, Marcos J., Kayed, Rakez, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Publicado 2012

Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death

por Tare, Meghana, Modi, Rohan M., Nainaparampil, Jaison J., Puli, Oorvashi Roy, Bedi, Shimpi, Fernandez-Funez, Pedro, Kango-Singh, Madhuri, Singh, Amit
Publicado 2011

In Vivo Generation of Neurotoxic Prion Protein: Role for Hsp70 in Accumulation of Misfolded Isoforms

por Fernandez-Funez, Pedro, Casas-Tinto, Sergio, Zhang, Yan, Gómez-Velazquez, Melisa, Morales-Garza, Marco A., Cepeda-Nieto, Ana C., Castilla, Joaquín, Soto, Claudio, Rincon-Limas, Diego E.
Publicado 2009

Purification of Transcripts and Metabolites from Drosophila Heads

por Jensen, Kurt, Sanchez-Garcia, Jonatan, Williams, Caroline, Khare, Swati, Mathur, Krishanu, Graze, Rita M., Hahn, Daniel A., McIntyre, Lauren M., Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Publicado 2013

Short Aβ peptides attenuate Aβ42 toxicity in vivo

por Moore, Brenda D., Martin, Jason, de Mena, Lorena, Sanchez, Jonatan, Cruz, Pedro E., Ceballos-Diaz, Carolina, Ladd, Thomas B., Ran, Yong, Levites, Yona, Kukar, Thomas L., Kurian, Justin J., McKenna, Robert, Koo, Edward H., Borchelt, David R., Janus, Christopher, Rincon-Limas, Diego, Fernandez-Funez, Pedro, Golde, Todd E.
Publicado 2018

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking

por Khare, Swati, Nick, Jerelyn A., Zhang, Yalan, Galeano, Kira, Butler, Brittany, Khoshbouei, Habibeh, Rayaprolu, Sruti, Hathorn, Tyisha, Ranum, Laura P. W., Smithson, Lisa, Golde, Todd E., Paucar, Martin, Morse, Richard, Raff, Michael, Simon, Julie, Nordenskjöld, Magnus, Wirdefeldt, Karin, Rincon-Limas, Diego E., Lewis, Jada, Kaczmarek, Leonard K., Fernandez-Funez, Pedro, Nick, Harry S., Waters, Michael F.
Publicado 2017