Considerations for improved performance of competition association assays analysed with the Motulsky–Mahan's “kinetics of competitive binding” model

por Georgi, Victoria, Dubrovskiy, Alexey, Steigele, Stephan, Fernández‐Montalván, Amaury E.
Publicado 2019

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

por Koo, Seong Joo, Fernández-Montalván, Amaury E., Badock, Volker, Ott, Christopher J., Holton, Simon J., von Ahsen, Oliver, Toedling, Joern, Vittori, Sarah, Bradner, James E., Gorjánácz, Mátyás
Publicado 2016

Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target

por Brzezinka, Krzysztof, Nevedomskaya, Ekaterina, Lesche, Ralf, Haegebarth, Andrea, ter Laak, Antonius, Fernández-Montalván, Amaury E., Eberspaecher, Uwe, Werbeck, Nicolas D., Moenning, Ursula, Siegel, Stephan, Haendler, Bernard, Eheim, Ashley L., Stresemann, Carlo
Publicado 2020

Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains

por Bouché, Léa, Christ, Clara D., Siegel, Stephan, Fernández-Montalván, Amaury E., Holton, Simon J., Fedorov, Oleg, ter Laak, Antonius, Sugawara, Tatsuo, Stöckigt, Detlef, Tallant, Cynthia, Bennett, James, Monteiro, Octovia, Díaz-Sáez, Laura, Siejka, Paulina, Meier, Julia, Pütter, Vera, Weiske, Jörg, Müller, Susanne, Huber, Kilian V. M., Hartung, Ingo V., Haendler, Bernard
Publicado 2017

Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2

por Eggert, Erik, Hillig, Roman C., Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D., ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E., Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J., Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H., Stellfeld, Timo, Stresemann, Carlo
Publicado 2016

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

por Fernández-Montalván, Amaury E., Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Puetter, Vera, Holton, Simon J., Stöckigt, Detlef, ter Laak, Antonius, Centrella, Paolo A., Clark, Matthew A., Dumelin, Christoph E., Sigel, Eric A., Soutter, Holly H., Troast, Dawn M., Zhang, Ying, Cuozzo, John W., Keefe, Anthony D., Roche, Didier, Rodeschini, Vincent, Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James M., Fedorov, Oleg, Huber, Kilian V. M., Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V., Gorjánácz, Mátyás
Publicado 2017