Programming of cardiometabolic health: the role of maternal and fetal hyperinsulinaemia

por Hufnagel, Antonia, Dearden, Laura, Fernandez-Twinn, Denise S, Ozanne, Susan E
Publicado 2022

Intrauterine programming of obesity and type 2 diabetes

por Fernandez-Twinn, Denise S., Hjort, Line, Novakovic, Boris, Ozanne, Susan E., Saffery, Richard
Publicado 2019

Lipid Metabolism Is Dysregulated before, during and after Pregnancy in a Mouse Model of Gestational Diabetes

por Furse, Samuel, Fernandez-Twinn, Denise S., Chiarugi, Davide, Koulman, Albert, Ozanne, Susan E.
Publicado 2021

Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition

por Martin-Gronert, Malgorzata S., Fernandez-Twinn, Denise S., Bushell, Martin, Siddle, Kenneth, Ozanne, Susan E.
Publicado 2016

A mouse model of gestational diabetes shows dysregulated lipid metabolism post-weaning, after return to euglycaemia

por Furse, Samuel, Fernandez-Twinn, Denise S., Beeson, Jessica H., Chiarugi, Davide, Ozanne, Susan E., Koulman, Albert
Publicado 2022

Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity

por Alfaradhi, Maria Z., Fernandez-Twinn, Denise S., Martin-Gronert, Malgorzata S., Musial, Barbara, Fowden, Abigail, Ozanne, Susan E.
Publicado 2014

Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice

por Nicholas, Lisa M., Nagao, Mototsugu, Kusinski, Laura C., Fernandez-Twinn, Denise S., Eliasson, Lena, Ozanne, Susan E.
Publicado 2019

Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice

por Berends, Lindsey M., Dearden, Laura, Tung, Yi Chun L., Voshol, Peter, Fernandez-Twinn, Denise S., Ozanne, Susan E.
Publicado 2018

Maternal Diet-induced Obesity Programs Cardiovascular Dysfunction in Adult Male Mouse Offspring Independent of Current Body Weight

por Blackmore, Heather L., Niu, Youguo, Fernandez-Twinn, Denise S., Tarry-Adkins, Jane L., Giussani, Dino A., Ozanne, Susan E.
Publicado 2014

Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner

por Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Aiken, Catherine E., Fernandez-Twinn, Denise S., Ozanne, Susan E.
Publicado 2021

Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE(−/−) mice

por Blackmore, Heather L., Piekarz, Ana V., Fernandez-Twinn, Denise S., Mercer, John R., Figg, Nichola, Bennett, Martin, Ozanne, Susan E.
Publicado 2012

The Programming of Cardiac Hypertrophy in the Offspring by Maternal Obesity Is Associated with Hyperinsulinemia, AKT, ERK, and mTOR Activation

por Fernandez-Twinn, Denise S., Blackmore, Heather L., Siggens, Lee, Giussani, Dino A., Cross, Christine M., Foo, Roger, Ozanne, Susan E.
Publicado 2012

A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats

por Tarry-Adkins, Jane L., Aiken, Catherine E., Ashmore, Thomas J., Fernandez-Twinn, Denise S., Chen, Jian-Hua, Ozanne, Susan E.
Publicado 2019

A Western‐style obesogenic diet alters maternal metabolic physiology with consequences for fetal nutrient acquisition in mice

por Musial, Barbara, Vaughan, Owen R., Fernandez‐Twinn, Denise S., Voshol, Peter, Ozanne, Susan E., Fowden, Abigail L., Sferruzzi‐Perri, Amanda N.
Publicado 2017

Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats

por Tarry-Adkins, Jane L., Fernandez-Twinn, Denise S., Chen, Jian Hua, Hargreaves, Iain P., Neergheen, Viruna, Aiken, Catherine E., Ozanne, Susan E.
Publicado 2016

Exercise alters the molecular pathways of insulin signaling and lipid handling in maternal tissues of obese pregnant mice

por Musial, Barbara, Fernandez‐Twinn, Denise S., Duque‐Guimaraes, Daniella, Carr, Sarah K., Fowden, Abigail L., Ozanne, Susan E., Sferruzzi‐Perri, Amanda N.
Publicado 2019

Nutritional programming of coenzyme Q: potential for prevention and intervention?

por Tarry-Adkins, Jane L., Fernandez-Twinn, Denise S., Chen, Jian-Hua, Hargreaves, Iain P., Martin-Gronert, Malgorzata S., McConnell, Josie M., Ozanne, Susan E.
Publicado 2014

Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms()

por Fernandez-Twinn, Denise S., Alfaradhi, Maria Z., Martin-Gronert, Malgorzata S., Duque-Guimaraes, Daniella E., Piekarz, Ana, Ferland-McCollough, David, Bushell, Martin, Ozanne, Susan E.
Publicado 2014

Coenzyme Q(10) prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth(1)

por Tarry-Adkins, Jane L, Fernandez-Twinn, Denise S, Hargreaves, Iain P, Neergheen, Viruna, Aiken, Catherine E, Martin-Gronert, Malgorzata S, McConnell, Josie M, Ozanne, Susan E
Publicado 2016

A high-throughput platform for detailed lipidomic analysis of a range of mouse and human tissues

por Furse, Samuel, Fernandez-Twinn, Denise S., Jenkins, Benjamin, Meek, Claire L., Williams, Huw E. L., Smith, Gordon C. S., Charnock-Jones, D. Stephen, Ozanne, Susan E., Koulman, Albert
Publicado 2020