Antagonism of the Muscarinic Acetylcholine Type 1 Receptor Enhances Mitochondrial Membrane Potential and Expression of Respiratory Chain Components via AMPK in Human Neuroblastoma...

por Naznin, Farhana, Waise, T. M. Zaved, Fernyhough, Paul
Publicado 2022

Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons

por Sabbir, Mohammad G., Calcutt, Nigel A., Fernyhough, Paul
Publicado 2018

Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress

por Zherebitskaya, Elena, Akude, Eli, Smith, Darrell R., Fernyhough, Paul
Publicado 2009

Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system

por Demaré, Sarah, Kothari, Asha, Calcutt, Nigel A., Fernyhough, Paul
Publicado 2021

Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria

por Chowdhury, Subir Roy, Djordjevic, Jelena, Albensi, Benedict C., Fernyhough, Paul
Publicado 2016

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

por Akude, Eli, Zherebitskaya, Elena, Chowdhury, Subir K. Roy, Smith, Darrell R., Dobrowsky, Rick T., Fernyhough, Paul
Publicado 2011

Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudom...

por Mink, Steven, Roy Chowdhury, Subir K., Gotes, Jose, Cheng, Zhao-Qin, Kasian, Krika, Fernyhough, Paul
Publicado 2016

Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1

por Aghanoori, Mohamad-Reza, Margulets, Vicky, Smith, Darrell R., Kirshenbaum, Lorrie A., Gitler, Daniel, Fernyhough, Paul
Publicado 2021

Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice

por Djordjevic, Jelena, Roy Chowdhury, Subir, Snow, Wanda M., Perez, Claudia, Cadonic, Chris, Fernyhough, Paul, Albensi, Benedict C.
Publicado 2020

Sensory neurons derived from diabetic rats have diminished internal Ca(2+) stores linked to impaired re-uptake by the endoplasmic reticulum

por Zherebitskaya, Elena, Schapansky, Jason, Akude, Eli, Smith, Darrell R, Van der Ploeg, Randy, Solovyova, Natasha, Verkhratsky, Alexei, Fernyhough, Paul
Publicado 2012

Activation of Cannabinoid Receptors Attenuates Endothelin-1–Induced Mitochondrial Dysfunction in Rat Ventricular Myocytes

por Lu, Yan, Lee, Danielle I., Roy Chowdhury, Subir, Lu, Ping, Kamboj, Amit, Anderson, Christopher M., Fernyhough, Paul, Anderson, Hope D.
Publicado 2020

Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

por Chowdhury, Subir K. Roy, Zherebitskaya, Elena, Smith, Darrell R., Akude, Eli, Chattopadhyay, Sharmila, Jolivalt, Corinne G., Calcutt, Nigel A., Fernyhough, Paul
Publicado 2010

Temporal dystrophic remodeling within the intrinsic cardiac nervous system of the streptozotocin-induced diabetic rat model

por Menard, Chantalle E, Durston, Melanie, Zherebitskaya, Elena, Smith, Darrell R, Freed, Darren, Glazner, Gordon W, Tian, Ganghong, Fernyhough, Paul, Arora, Rakesh C
Publicado 2014

Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons

por Saleh, Ali, Roy Chowdhury, Subir K, Smith, Darrell R, Balakrishnan, Savitha, Tessler, Lori, Schartner, Emily, Bilodeau, Andre, Van Der Ploeg, Randy, Fernyhough, Paul
Publicado 2013

Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-κB

por Snow, Wanda M., Cadonic, Chris, Cortes-Perez, Claudia, Roy Chowdhury, Subir K., Djordjevic, Jelena, Thomson, Ella, Bernstein, Michael J., Suh, Miyoung, Fernyhough, Paul, Albensi, Benedict C.
Publicado 2018

Early passaging of mesenchymal stem cells does not instigate significant modifications in their immunological behavior

por Sareen, Niketa, Sequiera, Glen Lester, Chaudhary, Rakesh, Abu-El-Rub, Ejlal, Chowdhury, Subir Roy, Sharma, Vikram, Surendran, Arun, Moudgil, Meenal, Fernyhough, Paul, Ravandi, Amir, Dhingra, Sanjiv
Publicado 2018

Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes

por Aghanoori, Mohamad-Reza, Smith, Darrell R., Shariati-Ievari, Shiva, Ajisebutu, Andrew, Nguyen, Annee, Desmond, Fiona, Jesus, Carlos H.A., Zhou, Xiajun, Calcutt, Nigel A., Aliani, Michel, Fernyhough, Paul
Publicado 2018

Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases

por Sequiera, Glen Lester, Srivastava, Abhay, Sareen, Niketa, Yan, Weiang, Alagarsamy, Keshav Narayan, Verma, Elika, Aghanoori, Mohamad Reza, Aliani, Michel, Kumar, Ashok, Fernyhough, Paul, Rockman-Greenberg, Cheryl, Dhingra, Sanjiv
Publicado 2022

Sex-Specific Effects of Chronic Creatine Supplementation on Hippocampal-Mediated Spatial Cognition in the 3xTg Mouse Model of Alzheimer’s Disease

por Snow, Wanda M., Cadonic, Chris, Cortes-Perez, Claudia, Adlimoghaddam, Aida, Roy Chowdhury, Subir K., Thomson, Ella, Anozie, Adama, Bernstein, Michael J., Gough, Kathleen, Fernyhough, Paul, Suh, Miyoung, Albensi, Benedict C.
Publicado 2020

Muscarinic Toxin 7 Signals Via Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration

por Saleh, Ali, Sabbir, Mohammad Golam, Aghanoori, Mohamad-Reza, Smith, Darrell R., Roy Chowdhury, Subir K., Tessler, Lori, Brown, Jennifer, Gedarevich, Eva, Kassahun, Markos Z., Frizzi, Katie, Calcutt, Nigel A., Fernyhough, Paul
Publicado 2020