ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

por Khiabanian, Hossein, Van Vlierberghe, Pieter, Palomero, Teresa, Ferrando, Adolfo A, Rabadan, Raul
Publicado 2010

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding

por Margolin, Adam A, Palomero, Teresa, Ferrando, Adolfo A, Califano, Andrea, Stolovitzky, Gustavo
Publicado 2007

Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

por Chang, Yoon Soo, Gills, Joell J., Kawabata, Shigeru, Onozawa, Masahiro, Della Gatta, Giusy, Ferrando, Adolfo A., Aplan, Peter D., Dennis, Phillip A.
Publicado 2023

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

por González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, José Luis, Ferrando, Adolfo A., Toribio, María L.
Publicado 2009

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

por González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, José Luis, Ferrando, Adolfo A., Toribio, María L.
Publicado 2009

Leukemia-specific delivery of mutant NOTCH1 targeted therapy

por Roti, Giovanni, Qi, Jun, Kitara, Samuel, Sanchez-Martin, Marta, Saur Conway, Amy, Varca, Anthony C., Su, Angela, Wu, Lei, Kung, Andrew L., Ferrando, Adolfo A., Bradner, James E., Stegmaier, Kimberly
Publicado 2018

N-Me, a long range oncogenic enhancer in T-cell acute lymphoblastic leukemia

por Herranz, Daniel, Ambesi-Impiombato, Alberto, Palomero, Teresa, Schnell, Stephanie A., Belver, Laura, Wendorff, Agnieszka A., Xu, Luyao, Castillo-Martin, Mireia, Llobet-Navás, David, Cardo, Carlos Cordon, Clappier, Emmanuelle, Soulier, Jean, Ferrando, Adolfo A.
Publicado 2014

The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

por Mandal, Malay, Borowski, Christine, Palomero, Teresa, Ferrando, Adolfo A., Oberdoerffer, Philipp, Meng, Fanyong, Ruiz-Vela, Antonio, Ciofani, Maria, Zuniga-Pflucker, Juan-Carlos, Screpanti, Isabella, Look, A. Thomas, Korsmeyer, Stanley J., Rajewsky, Klaus, von Boehmer, Harald, Aifantis, Iannis
Publicado 2005

ETV6 mutations in early immature human T cell leukemias

por Van Vlierberghe, Pieter, Ambesi-Impiombato, Alberto, Perez-Garcia, Arianne, Haydu, J. Erika, Rigo, Isaura, Hadler, Michael, Tosello, Valeria, Della Gatta, Giusy, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H., Luger, Selina M., Rowe, Jacob M., Rue, Montserrat, Ferrando, Adolfo A.
Publicado 2011

Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL

por Gatta, Giusy Della, Palomero, Teresa, Perez-Garcia, Arianne, Ambesi-Impiombato, Alberto, Bansal, Mukesh, Carpenter, Zachary W., De Keersmaecker, Kim, Sole, Xavier, Xu, Luyao, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H, Rowe, Jacob M, Meijerink, Jules P, Califano, Andrea, Ferrando, Adolfo A.
Publicado 2012

Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies

por Cordo’, Valentina, Meijer, Mariska T., Hagelaar, Rico, de Goeij-de Haas, Richard R., Poort, Vera M., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Oshima, Koichi, Ferrando, Adolfo A., Zaman, Guido J. R., Jimenez, Connie R., Meijerink, Jules P. P.
Publicado 2022

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia

por Kourtis, Nikos, Lazaris, Charalampos, Hockemeyer, Kathryn, Balandrán, Juan Carlos, Jimenez, Alejandra R., Mullenders, Jasper, Gong, Yixiao, Trimarchi, Thomas, Bhatt, Kamala, Hu, Hai, Shrestha, Liza, Ambesi-Impiombato, Alberto, Kelliher, Michelle, Paietta, Elisabeth, Chiosis, Gabriela, Guzman, Monica L., Ferrando, Adolfo A., Tsirigos, Aristotelis, Aifantis, Iannis
Publicado 2018

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia

por Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A., Castillo, Mireia, Haydu, J. Erika, Márquez, Javier, Matés, José M., Kung, Andrew L., Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J., Ferrando, Adolfo A.
Publicado 2015

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

por Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
Publicado 2018

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL

por Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy
Publicado 2022

Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia

por Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
Publicado 2018

Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

por Cortes, Jose R., Filip, Ioan, Albero, Robert, Patiño-Galindo, Juan A., Quinn, S. Aidan, Lin, Wen-Hsuan W., Laurent, Anouchka P., Shih, Bobby B., Brown, Jessie A., Cooke, Anisha J., Mackey, Adam, Einson, Jonah, Zairis, Sakellarios, Rivas-Delgado, Alfredo, Antonella Laginestra, Maria, Pileri, Stefano, Campo, Elias, Bhagat, Govind, Ferrando, Adolfo A., Rabadan, Raul, Palomero, Teresa
Publicado 2022

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

por Morgado-Palacin, Lucia, Brown, Jessie A., Martinez, Thomas F., Garcia-Pedrero, Juana M., Forouhar, Farhad, Quinn, S. Aidan, Reglero, Clara, Vaughan, Joan, Heydary, Yasamin Hajy, Donaldson, Cynthia, Rodriguez-Perales, Sandra, Allonca, Eva, Granda-Diaz, Rocio, Fernandez, Agustin F., Fraga, Mario F., Kim, Arianna L., Santos-Juanes, Jorge, Owens, David M., Rodrigo, Juan P., Saghatelian, Alan, Ferrando, Adolfo A.
Publicado 2023

Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia

por Ntziachristos, Panagiotis, Tsirigos, Aristotelis, Welstead, Grant, Trimarchi, Thomas, Bakogianni, Sofia, Xu, Luyao, Loizou, Evangelia, Holmfeldt, Linda, Strikoudis, Alexandros, King, Bryan, Mullanders, Jasper, Becksfort, Jared, Nedjic, Jelena, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., Tonon, Giovanni, Satoh, Takashi, Kruidenier, Laurens, Prinjha, Rab, Akira, Shizuo, Van Vlierberghe, Pieter, Ferrando, Adolfo A., Jaenisch, Rudolf, Mullighan, Charles G., Aifantis, Iannis
Publicado 2014

A selective BCL-X(L) PROTAC degrader achieves safe and potent antitumor activity

por Khan, Sajid, Zhang, Xuan, Lv, Dongwen, Zhang, Qi, He, Yonghan, Zhang, Peiyi, Liu, Xingui, Thummuri, Dinesh, Yuan, Yaxia, Wiegand, Janet S., Pei, Jing, Zhang, Weizhou, Sharma, Abhisheak, McCurdy, Christopher R., Kuruvilla, Vinitha M., Baran, Natalia, Ferrando, Adolfo A., Kim, Yong-mi, Rogojina, Anna, Houghton, Peter J., Huang, Guangcun, Hromas, Robert, Konopleva, Marina, Zheng, Guangrong, Zhou, Daohong
Publicado 2019