Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

por Unni, Arun M, Harbourne, Bryant, Oh, Min Hee, Wild, Sophia, Ferrarone, John R, Lockwood, William W, Varmus, Harold
Publicado 2018

Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1

por Fei, Dennis Liang, Zhen, Tao, Durham, Benjamin, Ferrarone, John, Zhang, Tuo, Garrett, Lisa, Yoshimi, Akihide, Abdel-Wahab, Omar, Bradley, Robert K., Liu, Paul, Varmus, Harold
Publicado 2018

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

por Stein, Benjamin D., Ferrarone, John R., Gardner, Eric E., Chang, Jae Won, Wu, David, Hollstein, Pablo E., Liang, Roger J., Yuan, Min, Chen, Qiuying, Coukos, John S., Sindelar, Miriam, Ngo, Bryan, Gross, Steven S., Shaw, Reuben J., Zhang, Chen, Asara, John M., Moellering, Raymond E., Varmus, Harold, Cantley, Lewis C.
Publicado 2023