Lyso-glycosphingolipids: presence and consequences

por van Eijk, Marco, Ferraz, Maria J., Boot, Rolf G., Aerts, Johannes M.F.G.
Publicado 2020

Biochemical response to substrate reduction therapy versus enzyme replacement therapy in Gaucher disease type 1 patients

por Smid, Bouwien E., Ferraz, Maria J., Verhoek, Marri, Mirzaian, Mina, Wisse, Patrick, Overkleeft, Herman S., Hollak, Carla E., Aerts, Johannes M.
Publicado 2016

Xylose‐Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase

por Su, Qin, Schröder, Sybrin P., Lelieveld, Lindsey T., Ferraz, Maria J., Verhoek, Marri, Boot, Rolf G., Overkleeft, Herman S., Aerts, Johannes M. F. G., Artola, Marta, Kuo, Chi‐Lin
Publicado 2021

Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases

por van der Gracht, Daniël, Rowland, Rhianna J., Roig-Zamboni, Véronique, Ferraz, Maria J., Louwerse, Max, Geurink, Paul P., Aerts, Johannes M. F. G., Sulzenbacher, Gerlind, Davies, Gideon J., Overkleeft, Herman S., Artola, Marta
Publicado 2023

Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector

por Dahl, Maria, Smith, Emma M.K., Warsi, Sarah, Rothe, Michael, Ferraz, Maria J., Aerts, Johannes M.F.G., Golipour, Azadeh, Harper, Claudia, Pfeifer, Richard, Pizzurro, Daniella, Schambach, Axel, Mason, Chris, Karlsson, Stefan
Publicado 2020

Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.

por Lelieveld, Lindsey T., Gerhardt, Sophie, Maas, Saskia, Zwiers, Kimberley C., de Wit, Claire, Beijk, Ernst H., Ferraz, Maria J., Artola, Marta, Meijer, Annemarie H., Tudorache, Christian, Salvatori, Daniela, Boot, Rolf G., Aerts, Johannes M.F.G.
Publicado 2022

Gluco-1H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor

por Schröder, Sybrin P., Wu, Liang, Artola, Marta, Hansen, Thomas, Offen, Wendy A., Ferraz, Maria J., Li, Kah-Yee, Aerts, Johannes M. F. G., van der Marel, Gijsbert A., Codée, Jeroen D. C., Davies, Gideon J., Overkleeft, Herman S.
Publicado 2018

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

por Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Publicado 2017

Human Alpha Galactosidases Transiently Produced in Nicotiana benthamiana Leaves: New Insights in Substrate Specificities with Relevance for Fabry Disease

por Kytidou, Kassiani, Beenakker, Thomas J. M., Westerhof, Lotte B., Hokke, Cornelis H., Moolenaar, Geri F., Goosen, Nora, Mirzaian, Mina, Ferraz, Maria J., de Geus, Mark, Kallemeijn, Wouter W., Overkleeft, Herman S., Boot, Rolf G., Schots, Arjen, Bosch, Dirk, Aerts, Johannes M. F. G.
Publicado 2017

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by β-xylosidase and transxylosidase reactions

por Boer, Daphne E., Mirzaian, Mina, Ferraz, Maria J., Zwiers, Kimberley C., Baks, Merel V., Hazeu, Marc D., Ottenhoff, Roelof, Marques, André R.A., Meijer, Rianne, Roos, Jonathan C.P., Cox, Timothy M., Boot, Rolf G., Pannu, Navraj, Overkleeft, Herman S., Artola, Marta, Aerts, Johannes M.
Publicado 2021

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors

por Beenakker, Thomas J. M., Wander, Dennis P. A., Offen, Wendy A., Artola, Marta, Raich, Lluís, Ferraz, Maria J., Li, Kah-Yee, Houben, Judith H. P. M., van Rijssel, Erwin R., Hansen, Thomas, van der Marel, Gijsbert A., Codée, Jeroen D. C., Aerts, Johannes M. F. G., Rovira, Carme, Davies, Gideon J., Overkleeft, Herman S.
Publicado 2017

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

por Lahav, Daniël, Liu, Bing, van den Berg, Richard J. B. H. N., van den Nieuwendijk, Adrianus M. C. H., Wennekes, Tom, Ghisaidoobe, Amar T., Breen, Imogen, Ferraz, Maria J., Kuo, Chi-Lin, Wu, Liang, Geurink, Paul P., Ovaa, Huib, van der Marel, Gijsbert A., van der Stelt, Mario, Boot, Rolf G., Davies, Gideon J., Aerts, Johannes M. F. G., Overkleeft, Herman S.
Publicado 2017

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

por Marques, André R. A., Mirzaian, Mina, Akiyama, Hisako, Wisse, Patrick, Ferraz, Maria J., Gaspar, Paulo, Ghauharali-van der Vlugt, Karen, Meijer, Rianne, Giraldo, Pilar, Alfonso, Pilar, Irún, Pilar, Dahl, Maria, Karlsson, Stefan, Pavlova, Elena V., Cox, Timothy M., Scheij, Saskia, Verhoek, Marri, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Pannu, Navraj S., van Eijk, Marco, Dekker, Nick, Boot, Rolf G., Overkleeft, Herman S., Blommaart, Edward, Hirabayashi, Yoshio, Aerts, Johannes M.
Publicado 2016