The genetics of pulmonary arterial hypertension in the post-BMPR2 era

por Fessel, Joshua P., Loyd, James E., Austin, Eric D.
Publicado 2011

Mitochondrial Haplogroups as a Risk Factor for Herpes Zoster

por Levinson, Rebecca T., Hulgan, Todd, Kalams, Spyros A., Fessel, Joshua P., Samuels, David C.
Publicado 2016

Real-world data for 21(st)-century medicine: The clinical and translational science awards program perspective

por Cure, Pablo, ElShourbagy Ferreira, Sanae, Fessel, Joshua P., Ossip, Deborah, Zand, Martin S., Steele, Scott J., Gersing, Kenneth, Hartshorn, Christopher M.
Publicado 2023

Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7

por Nguyen, Thuy T., Caito, Samuel W., Zackert, William E., West, James D., Zhu, Shijun, Aschner, Michael, Fessel, Joshua P., Roberts, L. Jackson
Publicado 2016

LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells

por Whang, Young Mi, Park, Serk In, Trenary, Irina A., Egnatchik, Robert A., Fessel, Joshua P., Kaufman, Jacob M., Carbone, David P., Young, Jamey D.
Publicado 2015

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition

por Hardeman, Keisha N., Peng, Chengwei, Paudel, Bishal B., Meyer, Christian T., Luong, Thong, Tyson, Darren R., Young, Jamey D., Quaranta, Vito, Fessel, Joshua P.
Publicado 2017

Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

por Fessel, Joshua P., Hamid, Rizwan, Wittmann, Bryan M., Robinson, Linda J., Blackwell, Tom, Tada, Yuji, Tanabe, Nobuhiro, Tatsumi, Koichiro, Hemnes, Anna R., West, James D.
Publicado 2012

Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension

por Trammell, Aaron W., Talati, Megha, Blackwell, Thomas R., Fortune, Niki L., Niswender, Kevin D., Fessel, Joshua P., Newman, John H., West, James D., Hemnes, Anna R.
Publicado 2017

Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines—Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials

por Buchman, Timothy G., Draghia-Akli, Ruxandra, Adam, Stacey J., Aggarwal, Neil R., Fessel, Joshua P., Higgs, Elizabeth S., Menetski, Joseph P., Read, Sarah W., Hughes, Eric A.
Publicado 2021

A Case Study of Dysfunctional Nicotinamide Metabolism in a 20-Year-Old Male

por DeBalsi, Karen L., Newman, John H., Sommerville, Laura J., Phillips, John A., Hamid, Rizwan, Cogan, Joy, Fessel, Joshua P., Evans, Anne M., Network, Undiagnosed Diseases, Kennedy, Adam D.
Publicado 2023

Oxidative injury is a common consequence of BMPR2 mutations

por Lane, Kirk L., Talati, Megha, Austin, Eric, Hemnes, Anna R., Johnson, Jennifer A., Fessel, Joshua P., Blackwell, Tom, Mernaugh, Ray L., Robinson, Linda, Fike, Candice, Roberts, L. Jackson, West, James
Publicado 2011

Low-grade albuminuria in pulmonary arterial hypertension

por Nickel, Nils P., de Jesus Perez, Vinicio A., Zamanian, Roham T., Fessel, Joshua P., Cogan, Joy D., Hamid, Rizwam, West, James D., de Caestecker, Mark P., Yang, Haichun, Austin, Eric D.
Publicado 2019

Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling

por Chow, Kelsey, Fessel, Joshua P., KaoriIhida-Stansbury, Schmidt, Eric P., Gaskill, Christa, Alvarez, Diego, Graham, Brian, Harrison, David G., Wagner, David H., Nozik-Grayck, Eva, West, James D., Klemm, Dwight J., Majka, Susan M.
Publicado 2013

Oxidative stress increases M(1)dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA

por Wauchope, Orrette R, Mitchener, Michelle M, Beavers, William N, Galligan, James J, Camarillo, Jeannie M, Sanders, William D, Kingsley, Philip J, Shim, Ha-Na, Blackwell, Thomas, Luong, Thong, deCaestecker, Mark, Fessel, Joshua P, Marnett, Lawrence J
Publicado 2018

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

por Egnatchik, Robert A., Brittain, Evan L., Shah, Amy T., Fares, Wassim H., Ford, H. James, Monahan, Ken, Kang, Christie J., Kocurek, Emily G., Zhu, Shijun, Luong, Thong, Nguyen, Thuy T., Hysinger, Erik, Austin, Eric D., Skala, Melissa C., Young, Jamey D., Roberts, L. Jackson, Hemnes, Anna R., West, James, Fessel, Joshua P.
Publicado 2017

Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation

por Pham, Ly, Komalavilas, Padmini, Eddie, Alex M., Thayer, Timothy E., Greenwood, Dalton L., Liu, Ken H., Weinberg, Jaclyn, Patterson, Andrew, Fessel, Joshua P., Boyd, Kelli L., Schafer, Jenny C., Kuck, Jamie L., Shaver, Aaron C., Flaherty, David K., Matlock, Brittany K., Wijers, Christiaan D. M., Serezani, C. Henrique, Jones, Dean P., Brittain, Evan L., Rathmell, Jeffrey C., Noto, Michael J.
Publicado 2022