Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis

por Rübbelke, Martin, Fiegen, Dennis, Bauer, Margit, Binder, Florian, Hamilton, James, King, Jim, Thamm, Sven, Nar, Herbert, Zeeb, Markus
Publicado 2020

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

por Schulte, Marius, Frick, Klaudia, Gnandt, Emmanuel, Jurkovic, Sascha, Burschel, Sabrina, Labatzke, Ramona, Aierstock, Karoline, Fiegen, Dennis, Wohlwend, Daniel, Gerhardt, Stefan, Einsle, Oliver, Friedrich, Thorsten
Publicado 2019

A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state

por Schnapp, Gisela, Neubauer, Heike, Büttner, Frank H., Handschuh, Sandra, Lingard, Iain, Heilker, Ralf, Klinder, Klaus, Prestle, Jürgen, Walter, Rainer, Wolff, Michael, Zeeb, Markus, Debaene, Francois, Nar, Herbert, Fiegen, Dennis
Publicado 2020

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

por Martin, Laetitia J., Koegl, Manfred, Bader, Gerd, Cockcroft, Xiao-Ling, Fedorov, Oleg, Fiegen, Dennis, Gerstberger, Thomas, Hofmann, Marco H., Hohmann, Anja F., Kessler, Dirk, Knapp, Stefan, Knesl, Petr, Kornigg, Stefan, Müller, Susanne, Nar, Herbert, Rogers, Catherine, Rumpel, Klaus, Schaaf, Otmar, Steurer, Steffen, Tallant, Cynthia, Vakoc, Christopher R., Zeeb, Markus, Zoephel, Andreas, Pearson, Mark, Boehmelt, Guido, McConnell, Darryl
Publicado 2016