Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma

por Eckardt, Luise, Prange-Barczynska, Maria, Hodson, Emma J, Fielding, James W, Cheng, Xiaotong, Lima, Joanna D C C, Kurlekar, Samvid, Douglas, Gillian, Ratcliffe, Peter J, Bishop, Tammie
Publicado 2021

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway

por Hodson, Emma J., Nicholls, Lynn G., Turner, Philip J., Llyr, Ronan, Fielding, James W., Douglas, Gillian, Ratnayaka, Indrika, Robbins, Peter A., Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Publicado 2015

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

por Fielding, James W., Hodson, Emma J., Cheng, Xiaotong, Ferguson, David J. P., Eckardt, Luise, Adam, Julie, Lip, Philomena, Maton‐Howarth, Matthew, Ratnayaka, Indrika, Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Publicado 2018

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2

por Bishop, Tammie, Talbot, Nick P, Turner, Philip J, Nicholls, Lynn G, Pascual, Alberto, Hodson, Emma J, Douglas, Gillian, Fielding, James W, Smith, Thomas G, Demetriades, Marina, Schofield, Christopher J, Robbins, Peter A, Pugh, Christopher W, Buckler, Keith J, Ratcliffe, Peter J
Publicado 2013

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

por Cheng, Xiaotong, Prange-Barczynska, Maria, Fielding, James W., Zhang, Minghao, Burrell, Alana L., Lima, Joanna D.C.C., Eckardt, Luise, Argles, Isobel L.A., Pugh, Christopher W., Buckler, Keith J., Robbins, Peter A., Hodson, Emma J., Bruick, Richard K., Collinson, Lucy M., Rastinejad, Fraydoon, Bishop, Tammie, Ratcliffe, Peter J.
Publicado 2020