The evolution of RNase P

por Engelke, David R., Fierke, Carol A.
Publicado 2015

A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P

por Liu, Xin, Chen, Yu, Fierke, Carol A.
Publicado 2014

Interplay between substrate recognition, 5′ end tRNA processing and methylation activity of human mitochondrial RNase P

por Karasik, Agnes, Fierke, Carol A., Koutmos, Markos
Publicado 2019

Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives

por Pithadia, Amit, Brender, Jeffrey R., Fierke, Carol A., Ramamoorthy, Ayyalusamy
Publicado 2016

Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation, and tRNA processing by mtRNase P

por Karasik, Agnes, Wilhelm, Catherine A., Fierke, Carol A., Koutmos, Markos
Publicado 2021

Combining Active Carbonic Anhydrase with Nanogels: Enzyme Protection and Zinc Sensing

por Si, Di, Nie, Guochao, Hurst, Tamiika K, Fierke, Carol A, Kopelman, Raoul
Publicado 2021

Gambogic acid and juglone inhibit RNase P through distinct mechanisms

por Wu Meyers, Nancy, Karasik, Agnes, Kaitany, Kipchumba, Fierke, Carol A., Koutmos, Markos
Publicado 2022

Identification of a Novel Class of Farnesylation Targets by Structure-Based Modeling of Binding Specificity

por London, Nir, Lamphear, Corissa L., Hougland, James L., Fierke, Carol A., Schueler-Furman, Ora
Publicado 2011

Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

por Varga, Julia K., Diffley, Kelsey, Welker Leng, Katherine R., Fierke, Carol A., Schueler-Furman, Ora
Publicado 2022

Unexpected specificity within dynamic transcriptional protein–protein complexes

por Henley, Matthew J., Linhares, Brian M., Morgan, Brittany S., Cierpicki, Tomasz, Fierke, Carol A., Mapp, Anna K.
Publicado 2020

Differential substrate recognition by isozymes of plant protein-only Ribonuclease P

por Howard, Michael J., Karasik, Agnes, Klemm, Bradley P., Mei, Christine, Shanmuganathan, Aranganathan, Fierke, Carol A., Koutmos, Markos
Publicado 2016

The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions

por Klemm, Bradley P., Wu, Nancy, Chen, Yu, Liu, Xin, Kaitany, Kipchumba J., Howard, Michael J., Fierke, Carol A.
Publicado 2016

Ratiometric Zinc Biosensor Based on Bioluminescence Resonance Energy Transfer: Trace Metal Ion Determination with Tunable Response

por Matveeva, Evgenia G., Stoddard, Andrea K., Zeng, Hui-Hui, Franke, Graham, Bourne, Leslie, Fierke, Carol A., Thompson, Richard B.
Publicado 2022

Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release

por Daniel, Kevin B., Sullivan, Eric D., Chen, Yao, Chan, Joshua C., Jennings, Patricia A., Fierke, Carol A., Cohen, Seth M.
Publicado 2015

A cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and an antagonist for amylin fibrillation

por Sahoo, Bikash R., Genjo, Takuya, Nakayama, Takahiro W., Stoddard, Andrea K., Ando, Toshio, Yasuhara, Kazuma, Fierke, Carol A., Ramamoorthy, Ayyalusamy
Publicado 2019

Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P

por Klemm, Bradley P., Karasik, Agnes, Kaitany, Kipchumba J., Shanmuganathan, Aranganathan, Henley, Matthew J., Thelen, Adam Z., Dewar, Allison J.L., Jackson, Nathaniel D., Koutmos, Markos, Fierke, Carol A.
Publicado 2017

Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators

por Henderson, Andrew R., Henley, Matthew J., Foster, Nicholas J., Peiffer, Amanda L., Beyersdorf, Matthew S., Stanford, Kevon D., Sturlis, Steven M., Linhares, Brian M., Hill, Zachary B., Wells, James A., Cierpicki, Tomasz, Brooks, Charles L., Fierke, Carol A., Mapp, Anna K.
Publicado 2018

An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

por Olson, David E., Udeshi, Namrata D., Wolfson, Noah A., Pitcairn, Carol Ann, Sullivan, Eric D., Jaffe, Jacob D., Svinkina, Tanya, Natoli, Ted, Lu, Xiaodong, Paulk, Joshiawa, McCarren, Patrick, Wagner, Florence F., Barker, Doug, Howe, Eleanor, Lazzaro, Fanny, Gale, Jennifer P., Zhang, Yan-Ling, Subramanian, Aravind, Fierke, Carol A., Carr, Steven A., Holson, Edward B.
Publicado 2014