Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness

por Scarcelli, John J., Hone, Megan, Beal, Kathryn, Ortega, Alejaida, Figueroa, Bruno, Starkey, Jason A., Anderson, Karin
Publicado 2018

Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody

por Sebastião, Maria João, Hoffman, Michael, Escandell, José, Tousi, Fatemeh, Zhang, Jin, Figueroa, Bruno, DeMaria, Christine, Gomes-Alves, Patrícia
Publicado 2023

Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses

por Sumit, Madhuresh, Dolatshahi, Sepideh, Chu, An-Hsiang Adam, Cote, Kaffa, Scarcelli, John J., Marshall, Jeffrey K., Cornell, Richard J., Weiss, Ron, Lauffenburger, Douglas A., Mulukutla, Bhanu Chandra, Figueroa, Bruno
Publicado 2019

Evolution of a comprehensive, orthogonal approach to sequence variant analysis for biotherapeutics

por Lin, T. Jennifer, Beal, Kathryn M., Brown, Paul W., DeGruttola, Heather S., Ly, Mellisa, Wang, Wenge, Chu, Chia H., Dufield, Robert L., Casperson, Gerald F., Carroll, James A., Friese, Olga V., Figueroa, Bruno, Marzilli, Lisa A., Anderson, Karin, Rouse, Jason C.
Publicado 2018