Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis

por Serra, Rosa, Johnson, Mahlon, Filvaroff, Ellen H., LaBorde, James, Sheehan, Daniel M., Derynck, Rik, Moses, Harold L.
Publicado 1997

A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms

por Wolin, Edward, Mita, Alain, Mahipal, Amit, Meyer, Tim, Bendell, Johanna, Nemunaitis, John, Munster, Pam N., Paz-Ares, Luis, Filvaroff, Ellen H., Li, Shaoyi, Hege, Kristen, de Haan, Hans, Mita, Monica
Publicado 2019

First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy

por Munster, Pamela, Mita, Monica, Mahipal, Amit, Nemunaitis, John, Massard, Christophe, Mikkelsen, Tom, Cruz, Cristina, Paz-Ares, Luis, Hidalgo, Manuel, Rathkopf, Dana, Blumenschein Jr, George, Smith, David C, Eichhorst, Barbara, Cloughesy, Tim, Filvaroff, Ellen H, Li, Shaoyi, Raymon, Heather, de Haan, Hans, Hege, Kristen, Bendell, Johanna C
Publicado 2019

Clinical activity of CC‐90011, an oral, potent, and reversible LSD1 inhibitor, in advanced malignancies

por Hollebecque, Antoine, Salvagni, Stefania, Plummer, Ruth, Niccoli, Patricia, Capdevila, Jaume, Curigliano, Giuseppe, Moreno, Victor, de Braud, Filippo, de Villambrosia, Sonia Gonzalez, Martin‐Romano, Patricia, Baudin, Eric, Arias, Marina, de Alvaro, Juan, Parra‐Palau, Josep L., Sánchez‐Pérez, Tania, Aronchik, Ida, Filvaroff, Ellen H., Lamba, Manisha, Nikolova, Zariana, de Bono, Johann S.
Publicado 2022

SMG1, a nonsense‐mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma

por Leeksma, Alexander C., Derks, Ingrid A. M., Garrick, Brett, Jongejan, Aldo, Colombo, Martino, Bloedjes, Timon, Trowe, Torsten, Leisten, Jim C., Howarth, Michelle, Malek, Mehnaz, Mortensen, Deborah S., Blease, Kate, Groza, Mathew C., Narla, Rama Krishna, Loos, Remco, Kersten, Marie‐José, Moerland, Perry D., Guikema, Jeroen E. J., Kater, Arnon P., Eldering, Eric, Filvaroff, Ellen H.
Publicado 2022