Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH

por Finan, Brian, Parlee, Sebastian D., Yang, Bin
Publicado 2020

Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes

por Finan, Brian, Capozzi, Megan E., Campbell, Jonathan E.
Publicado 2020

Peptide Conjugates with Small Molecules Designed to Enhance Efficacy and Safety

por He, Rongjun, Finan, Brian, Mayer, John P., DiMarchi, Richard D.
Publicado 2019

OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

por Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Publicado 2019

Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes

por Capozzi, Megan E, DiMarchi, Richard D, Tschöp, Matthias H, Finan, Brian, Campbell, Jonathan E
Publicado 2018

A Facile Procedure for One-Pot Stable Conjugation of Two Proglucagon Cysteine-Containing Peptide Analogs

por He, Rongjun, Mowery, Stephanie A., Chabenne, Joseph, Finan, Brian, Mayer, John P., DiMarchi, Richard D.
Publicado 2021

The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor

por Fischer, Katrin, Finan, Brian, Clemmensen, Christoffer, van der Ploeg, Lex H. T., Tschöp, Matthias H., Müller, Timo D.
Publicado 2015

Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice

por Jall, Sigrid, Finan, Brian, Collden, Gustav, Fischer, Katrin, Dong, Xinzhong, Tschöp, Matthias H., Müller, Timo D., Clemmensen, Christoffer
Publicado 2019

Corrigendum to “Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice” [Molecular Metabolism 23 (2019) 75–81]

por Jall, Sigrid, Finan, Brian, Collden, Gustav, Fischer, Katrin, Dong, Xinzhong, Tschöp, Matthias H., Müller, Timo D., Clemmensen, Christoffer
Publicado 2019

SAT-655 Bile Acid Sequestration Synergistically Accelerates Glucagon Receptor-Stimulated Body Weight Loss in Diet-Induced Obese Mice

por Kim, Teayoun, Nason, Shelly R, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard D, Habegger, Kirk M
Publicado 2020

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism

por Mroz, Piotr A., Finan, Brian, Gelfanov, Vasily, Yang, Bin, Tschöp, Matthias H., DiMarchi, Richard D., Perez-Tilve, Diego
Publicado 2018

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

por Müller, Anne, Kleinau, Gunnar, Piechowski, Carolin L., Müller, Timo D., Finan, Brian, Pratzka, Juliane, Grüters, Annette, Krude, Heiko, Tschöp, Matthias, Biebermann, Heike
Publicado 2013

GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

por Schwenk, Robert W., Baumeier, Christian, Finan, Brian, Kluth, Oliver, Brauer, Christine, Joost, Hans-Georg, DiMarchi, Richard D., Tschöp, Matthias H., Schürmann, Annette
Publicado 2014

Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice

por Jall, Sigrid, Sachs, Stephan, Clemmensen, Christoffer, Finan, Brian, Neff, Frauke, DiMarchi, Richard D., Tschöp, Matthias H., Müller, Timo D., Hofmann, Susanna M.
Publicado 2017

Pharmacological antagonism of the incretin system protects against diet-induced obesity

por Svendsen, Berit, Capozzi, Megan E., Nui, Jingjing, Hannou, Sarah A., Finan, Brian, Naylor, Jacqueline, Ravn, Peter, D'Alessio, David A., Campbell, Jonathan E.
Publicado 2019

GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease

por Sachs, Stephan, Götz, Anna, Finan, Brian, Feuchtinger, Annette, DiMarchi, Richard D., Döring, Yvonne, Weber, Christian, Tschöp, Matthias H., Müller, Timo D., Hofmann, Susanna M.
Publicado 2023

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity

por Agrawal, Archita, Parlee, Sebastian, Perez-Tilve, Diego, Li, Pengyun, Pan, Jia, Mroz, Piotr A., Kruse Hansen, Ann Maria, Andersen, Birgitte, Finan, Brian, Kharitonenkov, Alexei, DiMarchi, Richard D.
Publicado 2018

Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice

por Knerr, Patrick J., Mowery, Stephanie A., Douros, Jonathan D., Premdjee, Bhavesh, Hjøllund, Karina Rahr, He, Yantao, Kruse Hansen, Ann Maria, Olsen, Anette K., Perez-Tilve, Diego, DiMarchi, Richard D., Finan, Brian
Publicado 2022

Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists

por Novikoff, Aaron, O'Brien, Shannon L., Bernecker, Miriam, Grandl, Gerald, Kleinert, Maximilian, Knerr, Patrick J., Stemmer, Kerstin, Klingenspor, Martin, Zeigerer, Anja, DiMarchi, Richard, Tschöp, Matthias H., Finan, Brian, Calebiro, Davide, Müller, Timo D.
Publicado 2021

Fibroblast activation protein (FAP) as a novel metabolic target

por Sánchez-Garrido, Miguel Angel, Habegger, Kirk M., Clemmensen, Christoffer, Holleman, Cassie, Müller, Timo D., Perez-Tilve, Diego, Li, Pengyun, Agrawal, Archita S., Finan, Brian, Drucker, Daniel J., Tschöp, Matthias H., DiMarchi, Richard D., Kharitonenkov, Alexei
Publicado 2016