A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

por Williams, Charles A. C., Gray, Nathanael S., Findlay, Greg M.
Publicado 2017

LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain

por Cornejo, Francisca, Cortés, Bastián I., Findlay, Greg M., Cancino, Gonzalo I.
Publicado 2021

Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self‐renewal

por Mullin, Nicholas P., Varghese, Joby, Colby, Douglas, Richardson, Julia M., Findlay, Greg M., Chambers, Ian
Publicado 2020

Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity

por Williams, Charles A.C., Fernandez-Alonso, Rosalia, Wang, Jinhua, Toth, Rachel, Gray, Nathanael S., Findlay, Greg M.
Publicado 2016

Activity-based probe profiling of RNF12 E3 ubiquitin ligase function in Tonne-Kalscheuer syndrome

por Bustos, Francisco, Mathur, Sunil, Espejo-Serrano, Carmen, Toth, Rachel, Hastie, C James, Virdee, Satpal, Findlay, Greg M
Publicado 2022

Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification

por Fernandez‐Alonso, Rosalia, Davidson, Lindsay, Hukelmann, Jens, Zengerle, Michael, Prescott, Alan R, Lamond, Angus, Ciulli, Alessio, Sapkota, Gopal P, Findlay, Greg M
Publicado 2017

An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations

por Segarra-Fas, Anna, Espejo-Serrano, Carmen, Bustos, Francisco, Zhou, Houjiang, Wang, Feng, Toth, Rachel, Macartney, Thomas, Bach, Ingolf, Nardocci, Gino, Findlay, Greg M.
Publicado 2022

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation

por Bustos, Francisco, Segarra-Fas, Anna, Chaugule, Viduth K., Brandenburg, Lennart, Branigan, Emma, Toth, Rachel, Macartney, Thomas, Knebel, Axel, Hay, Ronald T., Walden, Helen, Findlay, Greg M.
Publicado 2018

A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne–Kalscheuer syndrome

por Bustos, Francisco, Espejo-Serrano, Carmen, Segarra-Fas, Anna, Toth, Rachel, Eaton, Alison J., Kernohan, Kristin D., Wilson, Meredith J., Riley, Lisa G., Findlay, Greg M.
Publicado 2021

Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation

por Fernandez-Alonso, Rosalia, Bustos, Francisco, Budzyk, Manon, Kumar, Pankaj, Helbig, Andreas O., Hukelmann, Jens, Lamond, Angus I., Lanner, Fredrik, Zhou, Houjiang, Petsalaki, Evangelia, Findlay, Greg M.
Publicado 2020

The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins

por Harrington, Laura S., Findlay, Greg M., Gray, Alex, Tolkacheva, Tatiana, Wigfield, Simon, Rebholz, Heike, Barnett, Jill, Leslie, Nick R., Cheng, Susan, Shepherd, Peter R., Gout, Ivan, Downes, C. Peter, Lamb, Richard F.
Publicado 2004

Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling

por Bustos, Francisco, Segarra-Fas, Anna, Nardocci, Gino, Cassidy, Andrew, Antico, Odetta, Davidson, Lindsay, Brandenburg, Lennart, Macartney, Thomas J., Toth, Rachel, Hastie, C. James, Moran, Jennifer, Gourlay, Robert, Varghese, Joby, Soares, Renata F., Montecino, Martin, Findlay, Greg M.
Publicado 2020

An ERK5–KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells

por Brown, Helen A., Williams, Charles A.C., Zhou, Houjiang, Rios-Szwed, Diana, Fernandez-Alonso, Rosalia, Mansoor, Saria, McMulkin, Liam, Toth, Rachel, Gourlay, Robert, Peltier, Julien, Dieguez-Martinez, Nora, Trost, Matthias, Lizcano, Jose M., Stavridis, Marios P., Findlay, Greg M.
Publicado 2021