Rise in dermal CD11c(+) dendritic cells associates with early-stage development of psoriatic lesions

por Teunissen, Marcel B. M., Zheng, Ling, de Groot, Marjan, de Rie, Menno A., Fine, Jay S., Chen, Shu-Cheng
Publicado 2012

CCR2 and CXCR4 regulate peripheral blood monocyte pharmacodynamics and link to efficacy in experimental autoimmune encephalomyelitis

por Wang, Yuanfan, Cui, Long, Gonsiorek, Waldemar, Min, Soo-Hong, Anilkumar, Gopinadhan, Rosenblum, Stuart, Kozlowski, Joseph, Lundell, Daniel, Fine, Jay S, Grant, Ethan P
Publicado 2009

Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice

por Stanton, Michaela C, Chen, Shu-Cheng, Jackson, James V, Rojas-Triana, Alberto, Kinsley, David, Cui, Long, Fine, Jay S, Greenfeder, Scott, Bober, Loretta A, Jenh, Chung-Her
Publicado 2011

Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity

por Wang, Guoqing, Lou, Howard H., Salit, Jacqueline, Leopold, Philip L., Driscoll, Sharon, Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S., Thomas, Matthew J., Crystal, Ronald G.
Publicado 2019

Selective IL-23 Inhibition by Risankizumab Modulates the Molecular Profile in the Colon and Ileum of Patients With Active Crohn’s Disease: Results From a Randomised Phase II Biopsy...

por Visvanathan, Sudha, Baum, Patrick, Salas, Azucena, Vinisko, Richard, Schmid, Ramona, Grebe, Kristie M, Davis, Justin W, Wallace, Kori, Böcher, Wulf O, Padula, Steven J, Fine, Jay S, Panés, Julián
Publicado 2018

IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD

por Baker, Jonathan R., Fenwick, Peter S., Koss, Carolin K., Owles, Harriet B., Elkin, Sarah L., Fine, Jay, Thomas, Matthew, El Kasmi, Karim C., Barnes, Peter J., Donnelly, Louise E.
Publicado 2022

Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus

por Chalmers, Samantha A., Wen, Jing, Doerner, Jessica, Stock, Ariel, Cuda, Carla M., Makinde, Hadijat M., Perlman, Harris, Bosanac, Todd, Webb, Deborah, Nabozny, Gerald, Fine, Jay S., Klein, Elliott, Ramanujam, Meera, Putterman, Chaim
Publicado 2018

Systemic Biomarkers of Neutrophilic Inflammation, Tissue Injury and Repair in COPD Patients with Differing Levels of Disease Severity

por Cockayne, Debra A., Cheng, Donavan T., Waschki, Benjamin, Sridhar, Sriram, Ravindran, Palanikumar, Hilton, Holly, Kourteva, Galina, Bitter, Hans, Pillai, Sreekumar G., Visvanathan, Sudha, Müller, Kai-Christian, Holz, Olaf, Magnussen, Helgo, Watz, Henrik, Fine, Jay S.
Publicado 2012

Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton’s Tyrosine Kinase

por Chalmers, Samantha A., Doerner, Jessica, Bosanac, Todd, Khalil, Sara, Smith, Dustin, Harcken, Christian, Dimock, Janice, Der, Evan, Herlitz, Leal, Webb, Deborah, Seccareccia, Elise, Feng, Di, Fine, Jay S., Ramanujam, Meera, Klein, Elliott, Putterman, Chaim
Publicado 2016

A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection

por Jenh, Chung-Her, Cox, Mary Ann, Cui, Long, Reich, Eva-Pia, Sullivan, Lee, Chen, Shu-Cheng, Kinsley, David, Qian, Shiguang, Kim, Seong Heon, Rosenblum, Stuart, Kozlowski, Joseph, Fine, Jay S, Zavodny, Paul J, Lundell, Daniel
Publicado 2012

Dysregulation of club cell biology in idiopathic pulmonary fibrosis

por Zuo, Wu-Lin, Rostami, Mahboubeh R., LeBlanc, Michelle, Kaner, Robert J., O’Beirne, Sarah L., Mezey, Jason G., Leopold, Philip L., Quast, Karsten, Visvanathan, Sudha, Fine, Jay S., Thomas, Matthew J., Crystal, Ronald G.
Publicado 2020

Kinetic Assessment and Therapeutic Modulation of Metabolic and Inflammatory Profiles in Mice on a High-Fat and Cholesterol Diet

por Engstrom, Laura W., Bober, Loretta, Chen, Shu-Cheng, Fine, Jay S., Li, Ying, Stanton, Michaela C., Kinsley, David, Cui, Long, Jackson, James V., Rojas-Triana, Alberto, Lundell, Daniel, Laverty, Maureen, Gustafson, Eric L., Jenh, Chung-Her, Kowalski, Timothy J., Manfra, Denise J.
Publicado 2010

Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-cont...

por Visvanathan, Sudha, Daniluk, Stefan, Ptaszyński, Rafał, Müller-Ladner, Ulf, Ramanujam, Meera, Rosenstock, Bernd, Eleftheraki, Anastasia G, Vinisko, Richard, Petříková, Alena, Kellner, Herbert, Dokoupilova, Eva, Kwiatkowska, Brygida, Alten, Rieke, Schwabe, Christian, Baum, Patrick, Joseph, David, Fine, Jay S, Padula, Steven J, Steffgen, Jürgen
Publicado 2019

IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice

por Koss, Carolin K., Wohnhaas, Christian T., Baker, Jonathan R., Tilp, Cornelia, Przibilla, Michèl, Lerner, Carmen, Frey, Silvia, Keck, Martina, Williams, Cara M. M., Peter, Daniel, Ramanujam, Meera, Fine, Jay, Gantner, Florian, Thomas, Matthew, Barnes, Peter J., Donnelly, Louise E., El Kasmi, Karim C.
Publicado 2021

Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease

por Peng, Ruoqi, Sridhar, Sriram, Tyagi, Gaurav, Phillips, Jonathan E., Garrido, Rosario, Harris, Paul, Burns, Lisa, Renteria, Lorena, Woods, John, Chen, Leena, Allard, John, Ravindran, Palanikumar, Bitter, Hans, Liang, Zhenmin, Hogaboam, Cory M., Kitson, Chris, Budd, David C., Fine, Jay S., Bauer, Carla MT., Stevenson, Christopher S.
Publicado 2013

Cell-specific expression of lung disease risk-related genes in the human small airway epithelium

por Zuo, Wu-lin, Rostami, Mahboubeh R., Shenoy, Shushila A., LeBlanc, Michelle G., Salit, Jacqueline, Strulovici-Barel, Yael, O’Beirne, Sarah L., Kaner, Robert J., Leopold, Philip L., Mezey, Jason G., Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S., Thomas, Matthew J., Crystal, Ronald G.
Publicado 2020

Intraflagellar Transport Gene Expression Associated with Short Cilia in Smoking and COPD

por Hessel, Justina, Heldrich, Jonna, Fuller, Jennifer, Staudt, Michelle R., Radisch, Sharon, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J., Salit, Jacqueline, Yee-Levin, Jenny, Sridhar, Sriram, Pillai, Sreekumar, Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay, Stevenson, Christopher S., Crystal, Ronald G., Tilley, Ann E.
Publicado 2014

Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

por Wang, Guoqing, Wang, Rui, Strulovici-Barel, Yael, Salit, Jacqueline, Staudt, Michelle R., Ahmed, Joumana, Tilley, Ann E., Yee-Levin, Jenny, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J., Mezey, Jason G., Sridhar, Sriram, Pillai, Sreekumar G., Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay S., Stevenson, Christopher S., Crystal, Ronald G.
Publicado 2015

Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies

por Ganesan, Rajkumar, Raymond, Ernest L., Mennerich, Detlev, Woska, Joseph R., Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D., Canada, Keith A., Kroe-Barrett, Rachel, Fine, Jay S., Singh, Sanjaya, Mbow, M. Lamine
Publicado 2017