Cell-Based Delivery Approaches for DNA-Binding Domains to the Central Nervous System

por Deng, Peter, Halmai, Julian, Waldo, Jennifer J., Fink, Kyle D.
Publicado 2021

The iNs and Outs of Direct Reprogramming to Induced Neurons

por Carter, Jasmine L., Halmai, Julian A. N. M., Fink, Kyle D.
Publicado 2020

Emerging Gene and Small Molecule Therapies for the Neurodevelopmental Disorder Angelman Syndrome

por Copping, Nycole A., McTighe, Stephanie M., Fink, Kyle D., Silverman, Jill L.
Publicado 2021

Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells

por Deng, Peter, Torrest, Audrey, Pollock, Kari, Dahlenburg, Heather, Annett, Geralyn, Nolta, Jan A., Fink, Kyle D.
Publicado 2016

Developing stem cell therapies for juvenile and adult-onset Huntington’s disease

por Fink, Kyle D, Deng, Peter, Torrest, Audrey, Stewart, Heather, Pollock, Kari, Gruenloh, William, Annett, Geralyn, Tempkin, Teresa, Wheelock, Vicki, Nolta, Jan A
Publicado 2015

Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner

por O’Geen, Henriette, Bates, Sofie L., Carter, Sakereh S., Nisson, Karly A., Halmai, Julian, Fink, Kyle D., Rhie, Suhn K., Farnham, Peggy J., Segal, David J.
Publicado 2019

Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells

por Adhikari, Anna, Copping, Nycole A, Beegle, Julie, Cameron, David L, Deng, Peter, O’Geen, Henriette, Segal, David J, Fink, Kyle D, Silverman, Jill L, Anderson, Joseph S
Publicado 2021

Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models of Cdkl5 deficiency

por Adhikari, Anna, Buchanan, Fiona K B, Fenton, Timothy A, Cameron, David L, Halmai, Julian A N M, Copping, Nycole A, Fink, Kyle D, Silverman, Jill L
Publicado 2022

Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

por Fink, Kyle D, Rossignol, Julien, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Bavar, Angela M, Clerc, Steven, Lowrance, Steven A, Song, Cheng, Lescaudron, Laurent, Dunbar, Gary L
Publicado 2013

Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is depe...

por Rossignol, Julien, Fink, Kyle D, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Clerc, Steven, Bavar, Angela M, Lowrance, Steven A, Song, Cheng, Witte, Steven, Lescaudron, Laurent, Dunbar, Gary L
Publicado 2015

Artificial escape from XCI by DNA methylation editing of the CDKL5 gene

por Halmai, Julian A N M, Deng, Peter, Gonzalez, Casiana E, Coggins, Nicole B, Cameron, David, Carter, Jasmine L, Buchanan, Fiona K B, Waldo, Jennifer J, Lock, Samantha R, Anderson, Johnathon D, O’Geen, Henriette, Segal, David J, Nolta, Jan, Fink, Kyle D
Publicado 2020

Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion

por Yuan, Oliver, Lin, Clayton, Wagner, Joseph, Archard, Joehleen A., Deng, Peter, Halmai, Julian, Bauer, Gerhard, Fink, Kyle D., Fury, Brian, Perotti, Nicholas H., Walker, Jon E., Pollock, Kari, Apperson, Michelle, Butters, Janelle, Belafsky, Peter, Farwell, D. Gregory, Kuhn, Maggie, Nolta, Jan, Anderson, Johnathon D.
Publicado 2019

Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models

por Pollock, Kari, Dahlenburg, Heather, Nelson, Haley, Fink, Kyle D, Cary, Whitney, Hendrix, Kyle, Annett, Geralyn, Torrest, Audrey, Deng, Peter, Gutierrez, Joshua, Nacey, Catherine, Pepper, Karen, Kalomoiris, Stefanos, D Anderson, Johnathon, McGee, Jeannine, Gruenloh, William, Fury, Brian, Bauer, Gerhard, Duffy, Alexandria, Tempkin, Theresa, Wheelock, Vicki, Nolta, Jan A
Publicado 2016

Polyamine Metabolites as Biomarkers in Head and Neck Cancer Biofluids

por DeFelice, Brian C., Fiehn, Oliver, Belafsky, Peter, Ditterich, Constanze, Moore, Michael, Abouyared, Marianne, Beliveau, Angela M., Farwell, D. Gregory, Bewley, Arnaud F., Clayton, Shannon M., Archard, Joehleen A., Pavlic, Jordan, Rao, Shyam, Kuhn, Maggie, Deng, Peter, Halmai, Julian, Fink, Kyle D., Birkeland, Andrew C., Anderson, Johnathon D.
Publicado 2022

An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models

por Deng, Peter, Halmai, Julian A. N. M., Beitnere, Ulrika, Cameron, David, Martinez, Michele L., Lee, Charles C., Waldo, Jennifer J., Thongphanh, Krista, Adhikari, Anna, Copping, Nycole, Petkova, Stela P., Lee, Ruth D., Lock, Samantha, Palomares, Miranda, O’Geen, Henriette, Carter, Jasmine, Gonzalez, Casiana E., Buchanan, Fiona K. B., Anderson, Johnathan D., Fierro, Fernando A., Nolta, Jan A., Tarantal, Alice F., Silverman, Jill L., Segal, David J., Fink, Kyle D.
Publicado 2022