Novel Role of Src in Priming Pyk2 Phosphorylation

por Zhao, Ming, Finlay, Darren, Zharkikh, Irina, Vuori, Kristiina
Publicado 2016

3-Dimensional Culture Systems for Anti-Cancer Compound Profiling and High-Throughput Screening Reveal Increases in EGFR Inhibitor-Mediated Cytotoxicity Compared to Monolayer Cultur...

por Howes, Amy L., Richardson, Robyn D., Finlay, Darren, Vuori, Kristiina
Publicado 2014

Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins

por Finlay, Darren, Teriete, Peter, Vamos, Mitchell, Cosford, Nicholas D. P., Vuori, Kristiina
Publicado 2017

Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting Specifically Through the Caspase-8 Apoptotic Axis

por Finlay, Darren, Richardson, Robyn D., Landberg, Lisa K., Howes, Amy L., Vuori, Kristiina
Publicado 2010

Sceptrin, a Marine Natural Compound, Inhibits Cell Motility in a Variety of Cancer Cell Lines

por Cipres, Angel, O’Malley, Daniel P., Li, Ke, Finlay, Darren, Baran, Phil S., Vuori, Kristiina
Publicado 2009

Capture of circulating metastatic cancer cell clusters from a lung cancer patient can reveal a unique genomic profile and potential anti-metastatic molecular targets: A proof of co...

por Kouhmareh, Kourosh, Martin, Erika, Finlay, Darren, Bhadada, Anukriti, Hernandez-Vargas, Hector, Downey, Francisco, Allen, Jeffrey K., Teriete, Peter
Publicado 2023

Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes

por Poreba, Marcin, Rut, Wioletta, Vizovisek, Matej, Groborz, Katarzyna, Kasperkiewicz, Paulina, Finlay, Darren, Vuori, Kristiina, Turk, Dusan, Turk, Boris, Salvesen, Guy S., Drag, Marcin
Publicado 2018

Analysis of variability in high throughput screening data: applications to melanoma cell lines and drug responses

por Ding, Kuan-Fu, Finlay, Darren, Yin, Hongwei, Hendricks, William P.D., Sereduk, Chris, Kiefer, Jeffrey, Sekulic, Aleksandar, LoRusso, Patricia M., Vuori, Kristiina, Trent, Jeffrey M., Schork, Nicholas J.
Publicado 2017

Network Rewiring in Cancer: Applications to Melanoma Cell Lines and the Cancer Genome Atlas Patients

por Ding, Kuan-Fu, Finlay, Darren, Yin, Hongwei, Hendricks, William P. D., Sereduk, Chris, Kiefer, Jeffrey, Sekulic, Aleksandar, LoRusso, Patricia M., Vuori, Kristiina, Trent, Jeffrey M., Schork, Nicholas J.
Publicado 2018

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis

por Ding, Kuan-Fu, Petricoin, Emanuel F., Finlay, Darren, Yin, Hongwei, Hendricks, William P.D., Sereduk, Chris, Kiefer, Jeffrey, Sekulic, Aleksandar, LoRusso, Patricia M., Vuori, Kristiina, Trent, Jeffrey M., Schork, Nicholas J.
Publicado 2017

Single-cell multiomics reveals the complexity of TGFβ signalling to chromatin in iPSC-derived kidney organoids

por Davis, Jessica L., Kennedy, Ciaran, Clerkin, Shane, Treacy, Niall J., Dodd, Thomas, Moss, Catherine, Murphy, Alison, Brazil, Derek P., Cagney, Gerard, Brougham, Dermot F., Murad, Rabi, Finlay, Darren, Vuori, Kristiina, Crean, John
Publicado 2022

Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis

por Welsh, Kate, Milutinovic, Snezana, Ardecky, Robert J., Gonzalez-Lopez, Marcos, Ganji, Santhi Reddy, Teriete, Peter, Finlay, Darren, Riedl, Stefan, Matsuzawa, Shu-ichi, Pinilla, Clemencia, Houghten, Richard, Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado 2016

Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells

por Raveendra-Panickar, Dhanya, Finlay, Darren, Layng, Fabiana Izidro, Lambert, Lester J., Celeridad, Maria, Zhao, Ming, Barbosa, Karina, De Backer, Laurent J.S., Kwong, Elizabeth, Gosalia, Palak, Rodiles, Socorro, Holleran, John, Ardecky, Robert, Grotegut, Stefan, Olson, Steven, Hutchinson, John H., Pasquale, Elena B., Vuori, Kristiina, Deshpande, Aniruddha J., Cosford, Nicholas D.P., Tautz, Lutz
Publicado 2021

The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors

por Khateb, Ali, Deshpande, Anagha, Feng, Yongmei, Finlay, Darren, Lee, Joo Sang, Lazar, Ikrame, Fabre, Bertrand, Li, Yan, Fujita, Yu, Zhang, Tongwu, Yin, Jun, Pass, Ian, Livneh, Ido, Jeremias, Irmela, Burian, Carol, Mason, James R., Almog, Ronit, Horesh, Nurit, Ofran, Yishai, Brown, Kevin, Vuori, Kristiina, Jackson, Michael, Ruppin, Eytan, Deshpande, Aniruddha J., Ronai, Ze’ev A.
Publicado 2021