Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons

por Gokare, Prashanth, Navaraj, Arunasalam, Zhang, Shengliang, Motoyama, Noboru, Sung, Shen-Shu, Finnberg, Niklas K.
Publicado 2016

P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting

por Gokare, Prashanth, Finnberg, Niklas K., Abbosh, Phillip H., Dai, Jenny, Murphy, Maureen E., El-Deiry, Wafik S.
Publicado 2017

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

por Finnberg, Niklas K., Gokare, Prashanth, Lev, Avital, Grivennikov, Sergei I., MacFarlane, Alexander W., Campbell, Kerry S., Winters, Ryan M., Kaputa, Karen, Farma, Jeffrey M., Abbas, Abbas El-Sayed, Grasso, Luigi, Nicolaides, Nicholas C., El-Deiry, Wafik S.
Publicado 2017

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

por Teye, Emmanuel K., Sido, Abigail, Xin, Ping, Finnberg, Niklas K., Gokare, Prashanth, Kawasawa, Yuka I., Salzberg, Anna C., Shimko, Sara, Bayerl, Michael, Ehmann, W. Christopher, Claxton, David F., Rybka, Witold B., Drabick, Joseph J., Wang, Hong-Gang, Abraham, Thomas, El-Deiry, Wafik S., Brodsky, Robert A., Hohl, Raymond J., Pu, Jeffrey J.
Publicado 2017