Multisite rate control analysis identifies ribosomal scanning as the sole high‐capacity/low‐flux‐control step in mRNA translation

por Firczuk, Helena, Teahan, James, Mendes, Pedro, McCarthy, John E.G.
Publicado 2019

Minimum-noise production of translation factor eIF4G maps to a mechanistically determined optimal rate control window for protein synthesis

por Meng, Xiang, Firczuk, Helena, Pietroni, Paola, Westbrook, Richard, Dacheux, Estelle, Mendes, Pedro, McCarthy, John E.G.
Publicado 2017

An in vivo control map for the eukaryotic mRNA translation machinery

por Firczuk, Helena, Kannambath, Shichina, Pahle, Jürgen, Claydon, Amy, Beynon, Robert, Duncan, John, Westerhoff, Hans, Mendes, Pedro, McCarthy, John EG
Publicado 2013

The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs

por dos Santos Rodrigues, Fabio Henrique, Firczuk, Helena, Breeze, Alexander L, Cameron, Alexander D, Walko, Martin, Wilson, Andrew J, Zanchin, Nilson I T, McCarthy, John E G
Publicado 2019

Diauxic shift-dependent relocalization of decapping activators Dhh1 and Pat1 to polysomal complexes

por Drummond, Sheona P., Hildyard, John, Firczuk, Helena, Reamtong, Onrapak, Li, Ning, Kannambath, Shichina, Claydon, Amy J., Beynon, Robert J., Eyers, Claire E., McCarthy, John E. G.
Publicado 2011