Bordetella Adenylate Cyclase Toxin Mobilizes Its β(2) Integrin Receptor into Lipid Rafts to Accomplish Translocation across Target Cell Membrane in Two Steps

por Bumba, Ladislav, Masin, Jiri, Fiser, Radovan, Sebo, Peter
Publicado 2010

The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin

por Masin, Jiri, Roderova, Jana, Osickova, Adriana, Novak, Petr, Bumba, Ladislav, Fiser, Radovan, Sebo, Peter, Osicka, Radim
Publicado 2017

Residues 529 to 549 participate in membrane penetration and pore-forming activity of the Bordetella adenylate cyclase toxin

por Roderova, Jana, Osickova, Adriana, Sukova, Anna, Mikusova, Gabriela, Fiser, Radovan, Sebo, Peter, Osicka, Radim, Masin, Jiri
Publicado 2019

Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin

por Masin, Jiri, Osickova, Adriana, Sukova, Anna, Fiser, Radovan, Halada, Petr, Bumba, Ladislav, Linhartova, Irena, Osicka, Radim, Sebo, Peter
Publicado 2016

A Single Tim Translocase in the Mitosomes of Giardia intestinalis Illustrates Convergence of Protein Import Machines in Anaerobic Eukaryotes

por Pyrihová, Eva, Motyčková, Alžběta, Voleman, Luboš, Wandyszewska, Natalia, Fišer, Radovan, Seydlová, Gabriela, Roger, Andrew, Kolísko, Martin, Doležal, Pavel
Publicado 2018

Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains

por Micenková, Lenka, Bosák, Juraj, Kucera, Jiri, Hrala, Matěj, Dolejšová, Tereza, Šedo, Ondrej, Linke, Dirk, Fišer, Radovan, Šmajs, David
Publicado 2019

Outer membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins

por Látrová, Klára, Havlová, Noemi, Večeřová, Renata, Pinkas, Dominik, Bogdanová, Kateřina, Kolář, Milan, Fišer, Radovan, Konopásek, Ivo, Do Pham, Duy Dinh, Rejman, Dominik, Mikušová, Gabriela
Publicado 2021

Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins

por Lepesheva, Anna, Osickova, Adriana, Holubova, Jana, Jurnecka, David, Knoblochova, Sarka, Espinosa-Vinals, Carlos, Bumba, Ladislav, Skopova, Karolina, Fiser, Radovan, Osicka, Radim, Sebo, Peter, Masin, Jiri
Publicado 2021

Calcium Influx Rescues Adenylate Cyclase-Hemolysin from Rapid Cell Membrane Removal and Enables Phagocyte Permeabilization by Toxin Pores

por Fiser, Radovan, Masin, Jiri, Bumba, Ladislav, Pospisilova, Eva, Fayolle, Catherine, Basler, Marek, Sadilkova, Lenka, Adkins, Irena, Kamanova, Jana, Cerny, Jan, Konopasek, Ivo, Osicka, Radim, Leclerc, Claude, Sebo, Peter
Publicado 2012

Semi-synthetic puwainaphycin/minutissamide cyclic lipopeptides with improved antifungal activity and limited cytotoxicity

por Hájek, Jan, Bieringer, Sebastian, Voráčová, Kateřina, Macho, Markéta, Saurav, Kumar, Delawská, Kateřina, Divoká, Petra, Fišer, Radovan, Mikušová, Gabriela, Cheel, José, Fewer, David P., Vu, Dai Long, Paichlová, Jindřiška, Riepl, Herbert, Hrouzek, Pavel
Publicado 2021

Insights into the Mechanism of Action of Bactericidal Lipophosphonoxins

por Panova, Natalya, Zborníková, Eva, Šimák, Ondřej, Pohl, Radek, Kolář, Milan, Bogdanová, Kateřina, Večeřová, Renata, Seydlová, Gabriela, Fišer, Radovan, Hadravová, Romana, Šanderová, Hana, Vítovská, Dragana, Šiková, Michaela, Látal, Tomáš, Lovecká, Petra, Barvík, Ivan, Krásný, Libor, Rejman, Dominik
Publicado 2015

LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials

por Do Pham, Duy Dinh, Mojr, Viktor, Helusová, Michaela, Mikušová, Gabriela, Pohl, Radek, Dávidová, Eva, Šanderová, Hana, Vítovská, Dragana, Bogdanová, Kateřina, Večeřová, Renata, Sedláková, Miroslava Htoutou, Fišer, Radovan, Sudzinová, Petra, Pospíšil, Jiří, Benada, Oldřich, Křížek, Tomáš, Galandáková, Adéla, Kolář, Milan, Krásný, Libor, Rejman, Dominik
Publicado 2022