Selective ALDH3A1 Inhibition by Benzimidazole Analogues Increase Mafosfamide Sensitivity in Cancer Cells

por Parajuli, Bibek, Fishel, Melissa L., Hurley, Thomas D.
Publicado 2014

PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma

por Zeleniak, Ann E., Huang, Wei, Fishel, Melissa L., Hill, Reginald
Publicado 2017

Clinical and Preclinical Outcomes of Combining Targeted Therapy With Radiotherapy

por Elbanna, May, Chowdhury, Nayela N., Rhome, Ryan, Fishel, Melissa L.
Publicado 2021

Loss of MTSS1 results in increased metastatic potential in pancreatic cancer

por Zeleniak, Ann E, Huang, Wei, Brinkman, Mary K, Fishel, Melissa L, Hill, Reginald
Publicado 2017

APE1/Ref-1 – One Target with Multiple Indications: Emerging Aspects and New Directions

por Mijit, Mahmut, Caston, Rachel, Gampala, Silpa, Fishel, Melissa L., Fehrenbacher, Jill, Kelley, Mark R.
Publicado 2021

Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2

por Rogers, Sally, Zhang, Chengting, Anagnostidis, Vasilis, Liddle, Corin, Fishel, Melissa L., Gielen, Fabrice, Scholpp, Steffen
Publicado 2023

Anticancer Peptides Derived from Aldolase A and Induced Tumor-Suppressing Cells Inhibit Pancreatic Ductal Adenocarcinoma Cells

por Cui, Changpeng, Huo, Qingji, Xiong, Xue, Li, Kexin, Fishel, Melissa L., Li, Baiyan, Yokota, Hiroki
Publicado 2023

APE1/Ref‐1 knockdown in pancreatic ductal adenocarcinoma – characterizing gene expression changes and identifying novel pathways using single‐cell RNA sequencing

por Shah, Fenil, Goossens, Emery, Atallah, Nadia M., Grimard, Michelle, Kelley, Mark R., Fishel, Melissa L.
Publicado 2017

APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells

por McIlwain, David W., Fishel, Melissa L., Boos, Alexander, Kelley, Mark R., Jerde, Travis J.
Publicado 2017

CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS

por Richards, Katherine E., Zeleniak, Ann E., Fishel, Melissa L., Wu, Junmin, Littlepage, Laurie E., Hill, Reginald
Publicado 2016

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic

por Shah, Fenil, Logsdon, Derek, Messmann, Richard A., Fehrenbacher, Jill C., Fishel, Melissa L., Kelley, Mark R.
Publicado 2017

Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening

por Puls, T. J., Tan, Xiaohong, Husain, Mahera, Whittington, Catherine F., Fishel, Melissa L., Voytik-Harbin, Sherry L.
Publicado 2018

Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions

por Lin, Fang-Yi, Chang, Chun-Yi, Nguyen, Han, Li, Hudie, Fishel, Melissa L., Lin, Chien-Chi
Publicado 2023

Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer()()()

por Lee, Jiyoon, Yakubov, Bakhtiyor, Ivan, Cristina, Jones, David R., Caperell-Grant, Andrea, Fishel, Melissa, Cardenas, Horacio, Matei, Daniela
Publicado 2016

Exploring the Tumor-Suppressing Potential of PSCA in Pancreatic Ductal Adenocarcinoma

por Li, Kexin, Huo, Qingji, Minami, Kazumasa, Tamari, Keisuke, Ogawa, Kazuhiko, Na, Sungsoo, Fishel, Melissa L., Li, Bai-Yan, Yokota, Hiroki
Publicado 2023

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition

por Herrera-Perez, R. Marisol, Voytik-Harbin, Sherry L., Sarkaria, Jann N., Pollok, Karen E., Fishel, Melissa L., Rickus, Jenna L.
Publicado 2018

The inhibition of pancreatic cancer progression by K-Ras-overexpressing mesenchymal stem cell-derived secretomes

por Huo, Qingji, Li, Kexin, Sun, Xun, Zhuang, Adam, Minami, Kazumasa, Tamari, Keisuke, Ogawa, Kazuhiko, Fishel, Melissa L., Li, Bai-Yan, Yokota, Hiroki
Publicado 2023

APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival

por Cardoso, Angelo A., Jiang, Yanlin, Luo, Meihua, Reed, April M., Shahda, Safi, He, Ying, Maitra, Anirban, Kelley, Mark R., Fishel, Melissa L.
Publicado 2012

RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cell...

por Mijit, Mahmut, Wireman, Randall, Armstrong, Lee, Gampala, Silpa, Hassan, Zonera, Schneeweis, Christian, Schneider, Guenter, Zhang, Chi, Fishel, Melissa L., Kelley, Mark R.
Publicado 2022

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

por Logsdon, Derek P., Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu T., Kamocka, Malgorzata, Jacobsen, Max H., Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.
Publicado 2018