QSSPN: dynamic simulation of molecular interaction networks describing gene regulation, signalling and whole-cell metabolism in human cells

por Fisher, Ciarán P., Plant, Nicholas J., Moore, J. Bernadette, Kierzek, Andrzej M.
Publicado 2013

Integration of Genome Scale Metabolic Networks and Gene Regulation of Metabolic Enzymes With Physiologically Based Pharmacokinetics

por Maldonado, Elaina M., Leoncikas, Vytautas, Fisher, Ciarán P., Moore, J. Bernadette, Plant, Nick J., Kierzek, Andrzej M.
Publicado 2017

SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp(®) simulator

por Khalidi, Hiba, Onasanwo, Anthonia, Islam, Barira, Jo, Heeseung, Fisher, Ciarán, Aidley, Rich, Gardner, Iain, Bois, Frederic Y.
Publicado 2022

Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease

por Maldonado, Elaina M., Fisher, Ciarán P., Mazzatti, Dawn J., Barber, Amy L., Tindall, Marcus J., Plant, Nicholas J., Kierzek, Andrzej M., Moore, J. Bernadette
Publicado 2018

Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids

por Rodrigues, Daniela, Coyle, Luke, Füzi, Barbara, Ferreira, Sofia, Jo, Heeseung, Herpers, Bram, Chung, Seung-Wook, Fisher, Ciarán, Kleinjans, Jos C. S., Jennen, Danyel, de Kok, Theo M.
Publicado 2022

A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids

por Rodrigues, Daniela, Herpers, Bram, Ferreira, Sofia, Jo, Heeseung, Fisher, Ciarán, Coyle, Luke, Chung, Seung-Wook, Kleinjans, Jos C. S., Jennen, Danyel G. J., de Kok, Theo M.
Publicado 2022

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

por Hodson, Leanne, Banerjee, Rajarshi, Rial, Belén, Arlt, Wiebke, Adiels, Martin, Boren, Jan, Marinou, Kyriakoula, Fisher, Ciaran, Mostad, Ingrid L., Stratton, Irene M., Barrett, P. Hugh R., Chan, Dick C., Watts, Gerald F., Harnden, Karin, Karpe, Fredrik, Fielding, Barbara A.
Publicado 2015

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

por Spanos, Christos, Maldonado, Elaina M., Fisher, Ciarán P., Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J., Bermúdez-Fajardo, Alexandra, Weeks, Mark E., Evans, Caroline, Corfe, Bernard M., Rabbani, Naila, Thornalley, Paul J., Miller, Michael H., Wang, Huan, Dillon, John F., Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Bernadette Moore, J.
Publicado 2018

Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

por Spanos, Christos, Maldonado, Elaina M., Fisher, Ciarán P., Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J., Bermúdez-Fajardo, Alexandra, Weeks, Mark E., Evans, Caroline, Corfe, Bernard M., Rabbani, Naila, Thornalley, Paul J., Miller, Michael H., Wang, Huan, Dillon, John F., Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Moore, J. Bernadette
Publicado 2018

A systems approach reveals species differences in hepatic stress response capacity

por Russomanno, Giusy, Sison-Young, Rowena, Livoti, Lucia A, Coghlan, Hannah, Jenkins, Rosalind E, Kunnen, Steven J, Fisher, Ciarán P, Reddyhoff, Dennis, Gardner, Iain, Rehman, Adeeb H, Fenwick, Stephen W, Jones, Andrew R, Vermeil De Conchard, Guy, Simonin, Gilles, Bertheux, Helene, Weaver, Richard J, Johnson, Robert L, Liguori, Michael J, Clausznitzer, Diana, Stevens, James L, Goldring, Christopher E, Copple, Ian M
Publicado 2023

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

por Krebs, Alice, van Vugt-Lussenburg, Barbara M. A., Waldmann, Tanja, Albrecht, Wiebke, Boei, Jan, ter Braak, Bas, Brajnik, Maja, Braunbeck, Thomas, Brecklinghaus, Tim, Busquet, Francois, Dinnyes, Andras, Dokler, Joh, Dolde, Xenia, Exner, Thomas E., Fisher, Ciarán, Fluri, David, Forsby, Anna, Hengstler, Jan G., Holzer, Anna-Katharina, Janstova, Zofia, Jennings, Paul, Kisitu, Jaffar, Kobolak, Julianna, Kumar, Manoj, Limonciel, Alice, Lundqvist, Jessica, Mihalik, Balázs, Moritz, Wolfgang, Pallocca, Giorgia, Ulloa, Andrea Paola Cediel, Pastor, Manuel, Rovida, Costanza, Sarkans, Ugis, Schimming, Johannes P., Schmidt, Bela Z., Stöber, Regina, Strassfeld, Tobias, van de Water, Bob, Wilmes, Anja, van der Burg, Bart, Verfaillie, Catherine M., von Hellfeld, Rebecca, Vrieling, Harry, Vrijenhoek, Nanette G., Leist, Marcel
Publicado 2020