Mapping the Structural Path for Allosteric Inhibition of a Short-Form ATP Phosphoribosyltransferase by Histidine

por Thomson, Catherine M., Alphey, Magnus S., Fisher, Gemma, da Silva, Rafael G.
Publicado 2019

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

por Madariaga-Marcos, Julene, Pastrana, Cesar L, Fisher, Gemma LM, Dillingham, Mark Simon, Moreno-Herrero, Fernando
Publicado 2019

Allosteric Activation Shifts the Rate-Limiting Step in a Short-Form ATP Phosphoribosyltransferase

por Fisher, Gemma, Thomson, Catherine M., Stroek, Rozanne, Czekster, Clarissa M., Hirschi, Jennifer S., da Silva, Rafael G.
Publicado 2018

Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation

por Fisher, Gemma, Corbella, Marina, Alphey, Magnus S., Nicholson, John, Read, Benjamin J., Kamerlin, Shina C. L., da Silva, Rafael G.
Publicado 2022

MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma

por Welsh, Kathryn G., Rousseau, Karine, Fisher, Gemma, Bonser, Luke R., Bradding, Peter, Brightling, Chris E., Thornton, David J., Gaillard, Erol A.
Publicado 2017

Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase

por Fisher, Gemma, Pečaver, Ennio, Read, Benjamin J., Leese, Susannah K., Laing, Erin, Dickson, Alison L., Czekster, Clarissa M., da Silva, Rafael G.
Publicado 2023

Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation

por Prince, Josh P., Bolla, Jani R., Fisher, Gemma L. M., Mäkelä, Jarno, Fournier, Marjorie, Robinson, Carol V., Arciszewska, Lidia K., Sherratt, David J.
Publicado 2021

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

por Sanders, Kelly, Lin, Chia-Liang, Smith, Abigail J., Cronin, Nora, Fisher, Gemma, Eftychidis, Vasileios, McGlynn, Peter, Savery, Nigel J., Wigley, Dale B., Dillingham, Mark S.
Publicado 2017

CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS

por Balaguer, Francisco de Asis, Aicart-Ramos, Clara, Fisher, Gemma LM, de Bragança, Sara, Martin-Cuevas, Eva M, Pastrana, Cesar L, Dillingham, Mark Simon, Moreno-Herrero, Fernando
Publicado 2021

Competitive binding of MatP and topoisomerase IV to the MukB hinge domain

por Fisher, Gemma LM, Bolla, Jani R, Rajasekar, Karthik V, Mäkelä, Jarno, Baker, Rachel, Zhou, Man, Prince, Josh P, Stracy, Mathew, Robinson, Carol V, Arciszewska, Lidia K, Sherratt, David J
Publicado 2021

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

por Fisher, Gemma LM, Pastrana, César L, Higman, Victoria A, Koh, Alan, Taylor, James A, Butterer, Annika, Craggs, Timothy, Sobott, Frank, Murray, Heath, Crump, Matthew P, Moreno-Herrero, Fernando, Dillingham, Mark S
Publicado 2017

Dynamic architecture of the Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF

por Rajasekar, Karthik V, Baker, Rachel, Fisher, Gemma L M, Bolla, Jani R, Mäkelä, Jarno, Tang, Minzhe, Zawadzka, Katarzyna, Koczy, Oliwia, Wagner, Florence, Robinson, Carol V, Arciszewska, Lidia K, Sherratt, David J
Publicado 2019

Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m(1)A22-tRNA methyltransferase TrmK

por Sweeney, Pamela, Galliford, Ashleigh, Kumar, Abhishek, Raju, Dinesh, Krishna, Naveen B., Sutherland, Emmajay, Leo, Caitlin J., Fisher, Gemma, Lalitha, Roopa, Muthuraj, Likith, Sigamani, Gladstone, Oehler, Verena, Synowsky, Silvia, Shirran, Sally L., Gloster, Tracey M., Czekster, Clarissa M., Kumar, Pravin, da Silva, Rafael G.
Publicado 2022