Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data

por Fishman, Pnina
Publicado 2022

Targeting the A(3) adenosine receptor to treat cytokine release syndrome in cancer immunotherapy

por Cohen, Shira, Fishman, Pnina
Publicado 2019

Namodenoson Inhibits the Growth of Pancreatic Carcinoma via Deregulation of the Wnt/β-catenin, NF-κB, and RAS Signaling Pathways

por Itzhak, Inbal, Bareket-Samish, Avital, Fishman, Pnina
Publicado 2023

Inhibition of IL-17 and IL-23 in Human Keratinocytes by the A(3) Adenosine Receptor Agonist Piclidenoson

por Cohen, Shira, Barer, Faina, Itzhak, Inbal, Silverman, Michael H., Fishman, Pnina
Publicado 2018

Targeting the A3 adenosine receptor to treat hepatocellular carcinoma: anti-cancer and hepatoprotective effects

por Fishman, Pnina, Stemmer, Salomon M., Bareket-Samish, Avital, Silverman, Michael H., Kerns, William D.
Publicado 2023

The A3 adenosine receptor agonist, namodenoson, ameliorates non-alcoholic steatohepatitis in mice

por Fishman, Pnina, Cohen, Shira, Itzhak, Inbal, Amer, Johnny, Salhab, Ahmad, Barer, Faina, Safadi, Rifaat
Publicado 2019

A(3) Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action

por Cohen, Shira, Barer, Faina, Bar-Yehuda, Sara, IJzerman, Adriaan P., Jacobson, Kenneth A., Fishman, Pnina
Publicado 2014

The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis

por Fishman, Pnina, Bar-Yehuda, Sara, Madi, Lea, Rath-Wolfson, Lea, Ochaion, Avivit, Cohen, Shira, Baharav, Ehud
Publicado 2006

Putative role of the adenosine A(3) receptor in the antiproliferative action of N(6)-(2-isopentenyl)adenosine

por Blad, Clara C., von Frijtag Drabbe Künzel, Jacobien K., de Vries, Henk, Mulder-Krieger, Thea, Bar-Yehuda, Sara, Fishman, Pnina, IJzerman, Adriaan P.
Publicado 2011

Randomised clinical trial: A phase 2 double‐blind study of namodenoson in non‐alcoholic fatty liver disease and steatohepatitis

por Safadi, Rifaat, Braun, Marius, Francis, Adi, Milgrom, Yael, Massarwa, Muhammad, Hakimian, David, Hazou, Wadi, Issachar, Assaf, Harpaz, Zivit, Farbstein, Motti, Itzhak, Inbal, Lev‐Cohain, Naama, Bareket‐Samish, Avital, Silverman, Michael H., Fishman, Pnina
Publicado 2021

Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A(3 )adenosine receptor expression

por Ochaion, Avivit, Bar-Yehuda, Sara, Cohn, Shira, Del Valle, Luis, Perez-Liz, Georginia, Madi, Lea, Barer, Faina, Farbstein, Motti, Fishman-Furman, Sari, Reitblat, Tatiana, Reitblat, Alexander, Amital, Howard, Levi, Yair, Molad, Yair, Mader, Reuven, Tishler, Moshe, Langevitz, Pnina, Zabutti, Alexander, Fishman, Pnina
Publicado 2006

Namodenoson in Advanced Hepatocellular Carcinoma and Child–Pugh B Cirrhosis: Randomized Placebo-Controlled Clinical Trial

por Stemmer, Salomon M., Manojlovic, Nebojsa S., Marinca, Mihai Vasile, Petrov, Petar, Cherciu, Nelly, Ganea, Doina, Ciuleanu, Tudor Eliade, Pusca, Ioana Adriana, Beg, Muhammad Shaalan, Purcell, William T., Croitoru, Adina-Emilia, Ilieva, Rumyana Nedyalkova, Natošević, Sladjana, Nita, Amedeia Lavinir, Kalev, Dimitar Nikolaev, Harpaz, Zivit, Farbstein, Motti, Silverman, Michael H., Bristol, David, Itzhak, Inbal, Fishman, Pnina
Publicado 2021