Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease

por Shaw, Joseph, Fishwick, Colin W.G., Harris, Mark
Publicado 2015

Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease

por Shaw, Joseph, Harris, Mark, Fishwick, Colin W.G.
Publicado 2015

Developments in Non-Intercalating Bacterial Topoisomerase Inhibitors: Allosteric and ATPase Inhibitors of DNA Gyrase and Topoisomerase IV

por Grossman, Scott, Fishwick, Colin W. G., McPhillie, Martin J.
Publicado 2023

Selective Phosphonylation of 5′-Adenosine Monophosphate (5′-AMP) via Pyrophosphite [PPi(III)]

por Kaye, Karl, Bryant, David E., Marriott, Katie E. R., Ohara, Shohei, Fishwick, Colin W. G., Kee, Terence P.
Publicado 2016

Recent developments in the structural characterisation of the IR and IGF1R: implications for the design of IR–IGF1R hybrid receptor modulators

por Turvey, Samuel J., McPhillie, Martin J., Kearney, Mark T., Muench, Stephen P., Simmons, Katie J., Fishwick, Colin W. G.
Publicado 2022

Structure-Based Identification and Characterization of Inhibitors of the Epilepsy-Associated K(Na)1.1 (KCNT1) Potassium Channel

por Cole, Bethan A., Johnson, Rachel M., Dejakaisaya, Hattapark, Pilati, Nadia, Fishwick, Colin W.G., Muench, Stephen P., Lippiat, Jonathan D.
Publicado 2020

Structure-switching M(3)L(2) Ir(iii) coordination cages with photo-isomerising azo-aromatic linkers

por Oldknow, Samuel, Martir, Diego Rota, Pritchard, Victoria E., Blitz, Mark A., Fishwick, Colin W. G., Zysman-Colman, Eli, Hardie, Michaele J.
Publicado 2018

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis

por Latham, Antony M., Kankanala, Jayakanth, Fearnley, Gareth W., Gage, Matthew C., Kearney, Mark T., Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B., Fishwick, Colin W. G., Ponnambalam, Sreenivasan
Publicado 2014

Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2((3)) by High-Throughput Virtual Screening and Automated Patch Clamp

por Wacker, Sören J, Jurkowski, Wiktor, Simmons, Katie J, Fishwick, Colin W G, Johnson, A Peter, Madge, David, Lindahl, Erik, Rolland, Jean-Francois, de Groot, Bert L
Publicado 2012

Assay Platform for Clinically Relevant Metallo-β-lactamases

por van Berkel, Sander S., Brem, Jürgen, Rydzik, Anna M., Salimraj, Ramya, Cain, Ricky, Verma, Anil, Owens, Raymond J., Fishwick, Colin W. G., Spencer, James, Schofield, Christopher J.
Publicado 2013

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc (1) complexes for structure-based drug discovery

por Amporndanai, Kangsa, Johnson, Rachel M., O’Neill, Paul M., Fishwick, Colin W. G., Jamson, Alexander H., Rawson, Shaun, Muench, Stephen P., Hasnain, S. Samar, Antonyuk, Svetlana V.
Publicado 2018

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

por Brem, Jürgen, Cain, Ricky, Cahill, Samuel, McDonough, Michael A., Clifton, Ian J., Jiménez-Castellanos, Juan-Carlos, Avison, Matthew B., Spencer, James, Fishwick, Colin W. G., Schofield, Christopher J.
Publicado 2016

Cyclic Boronates Inhibit All Classes of β-Lactamases

por Cahill, Samuel T., Cain, Ricky, Wang, David Y., Lohans, Christopher T., Wareham, David W., Oswin, Henry P., Mohammed, Jabril, Spencer, James, Fishwick, Colin W. G., McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Publicado 2017

Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

por Lang, Pauline A., Parkova, Anete, Leissing, Thomas M., Calvopiña, Karina, Cain, Ricky, Krajnc, Alen, Panduwawala, Tharindi D., Philippe, Jules, Fishwick, Colin W. G., Trapencieris, Peteris, Page, Malcolm G. P., Schofield, Christopher J., Brem, Jürgen
Publicado 2020

Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk

por King, Rhodri J., Schuett, Katharina, Tiede, Christian, Jankowski, Vera, John, Vicky, Trehan, Abhi, Simmons, Katie, Ponnambalam, Sreenivasan, Storey, Robert F., Fishwick, Colin W.G., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publicado 2020

De novo design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding region

por Orritt, Kyle M., Feng, Lipeng, Newell, Juliette F., Sutton, Jack N., Grossman, Scott, Germe, Thomas, Abbott, Lauren R., Jackson, Holly L., Bury, Benjamin K. L., Maxwell, Anthony, McPhillie, Martin J., Fishwick, Colin W. G.
Publicado 2022

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

por Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W. G., de Carvalho, Luiz Pedro S., Roper, David I.
Publicado 2017

Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone

por Majeed, Yasser, Tumova, Sarka, Green, Ben L., Seymour, Victoria A.L., Woods, Daniel M., Agarwal, Anil K., Naylor, Jacqueline, Jiang, Shannon, Picton, Helen M., Porter, Karen E., O’Regan, David J., Muraki, Katsuhiko, Fishwick, Colin W.G., Beech, David J.
Publicado 2012