APOEε4 and risk of Alzheimer’s disease – time to move forward

por Lefterov, Iliya, Fitz, Nicholas F., Lu, Yi, Koldamova, Radosveta
Publicado 2023

Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

por Fitz, Nicholas F., Barchowsky, Aaron, Koldamova, Radosveta, Lefterov, Iliya
Publicado 2022

Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer’s disease

por Fitz, Nicholas F., Wang, Jiebiao, Kamboh, M. Ilyas, Koldamova, Radosveta, Lefterov, Iliya
Publicado 2021

Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

por Fitz, Nicholas F., Sahu, Amrita, Lu, Yi, Ambrosio, Fabrisia, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2023

Memory deficits in APP23/Abca1(+/−) mice correlate with the level of Aβ oligomers

por Lefterov, Iliya, Fitz, Nicholas F, Cronican, Andrea, Lefterov, Preslav, Staufenbiel, Matthias, Koldamova, Radosveta
Publicado 2009

The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

por Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2018

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

por Nam, Kyong Nyon, Mounier, Anais, Fitz, Nicholas F., Wolfe, Cody, Schug, Jonathan, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2016

ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice

por Fitz, Nicholas F., Carter, Alexis Y., Tapias, Victor, Castranio, Emilie L., Kodali, Ravindra, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2017

ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

por Castranio, Emilie L., Wolfe, Cody M., Nam, Kyong Nyon, Letronne, Florent, Fitz, Nicholas F., Lefterov, Iliya, Koldamova, Radosveta
Publicado 2018

Genome-Wide Alteration of Histone H3K9 Acetylation Pattern in Mouse Offspring Prenatally Exposed to Arsenic

por Cronican, Andrea A., Fitz, Nicholas F., Carter, Alexis, Saleem, Muzamil, Shiva, Sruti, Barchowsky, Aaron, Koldamova, Radosveta, Schug, Jonathan, Lefterov, Iliya
Publicado 2013

Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

por Fitz, Nicholas F., Wolfe, Cody M., Playso, Brittany E., Biedrzycki, Richard J., Lu, Yi, Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2020

Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

por Carter, Alexis Y., Letronne, Florent, Fitz, Nicholas F., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Reeves, Valerie L., Kamboh, Hafsa, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2017

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

por Lefterov, Iliya, Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Letronne, Florent, Biedrzycki, Richard J., Kofler, Julia, Han, Xianlin, Wang, Jianing, Schug, Jonathan, Koldamova, Radosveta
Publicado 2019

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

por Nam, Kyong Nyon, Mounier, Anais, Wolfe, Cody M., Fitz, Nicholas F., Carter, Alexis Y., Castranio, Emilie L., Kamboh, Hafsa I., Reeves, Valerie L., Wang, Jianing, Han, Xianlin, Schug, Jonathan, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2017

Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease

por Fitz, Nicholas F., Nam, Kyong Nyon, Wolfe, Cody M., Letronne, Florent, Playso, Brittany E., Iordanova, Bistra E., Kozai, Takashi D. Y., Biedrzycki, Richard J., Kagan, Valerian E., Tyurina, Yulia Y., Han, Xianlin, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2021