Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

por Collin, Guillaume, Huna, Anda, Warnier, Marine, Flaman, Jean-Michel, Bernard, David
Publicado 2018

Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage

por Zerdoumi, Yasmine, Lanos, Raphaël, Raad, Sabine, Flaman, Jean-Michel, Bougeard, Gaëlle, Frebourg, Thierry, Tournier, Isabelle
Publicado 2017

Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage

por Zerdoumi, Yasmine, Lanos, Raphaël, Raad, Sabine, Flaman, Jean-Michel, Bougeard, Gaëlle, Frebourg, Thierry, Tournier, Isabelle
Publicado 2017

Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca(2+) Levels in Senescent Cells

por Raynard, Clotilde, Tessier, Nolwenn, Huna, Anda, Warnier, Marine, Flaman, Jean-Michel, Van Coppenolle, Fabien, Ducreux, Sylvie, Martin, Nadine, Bernard, David
Publicado 2022

Role of the LytSR Two-Component Regulatory System in Staphylococcus lugdunensis Biofilm Formation and Pathogenesis

por Dahyot, Sandrine, Oxaran, Virginie, Niepceron, Maïté, Dupart, Eddy, Legris, Stéphanie, Destruel, Laurie, Didi, Jennifer, Clamens, Thomas, Lesouhaitier, Olivier, Zerdoumi, Yasmine, Flaman, Jean-Michel, Pestel-Caron, Martine
Publicado 2020

Evidence That SARS-CoV-2 Induces Lung Cell Senescence: Potential Impact on COVID-19 Lung Disease

por Lipskaia, Larissa, Maisonnasse, Pauline, Fouillade, Charles, Sencio, Valentin, Pascal, Quentin, Flaman, Jean-Michel, Born, Emmanuelle, Londono-Vallejo, Arturo, Le Grand, Roger, Bernard, David, Trottein, François, Adnot, Serge
Publicado 2021

RSK3 switches cell fate: from stress-induced senescence to malignant progression

por Huna, Anda, Flaman, Jean-Michel, Lodillinsky, Catalina, Zhu, Kexin, Makulyte, Gabriela, Pakulska, Victoria, Coute, Yohann, Ruisseaux, Clémence, Saintigny, Pierre, Hernandez-Vargas, Hector, Defossez, Pierre-Antoine, Boissan, Mathieu, Martin, Nadine, Bernard, David
Publicado 2023

The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway

por Warnier, Marine, Flaman, Jean‐Michel, Chouabe, Christophe, Wiel, Clotilde, Gras, Baptiste, Griveau, Audrey, Blanc, Elena, Foy, Jean‐Philippe, Mathot, Pauline, Saintigny, Pierre, Van Coppenolle, Fabien, Vindrieux, David, Martin, Nadine, Bernard, David
Publicado 2018

Loss of Pla2r1 decreases cellular senescence and age‐related alterations caused by aging and Western diets

por Massemin, Amélie, Goehrig, Delphine, Flaman, Jean‐Michel, Jaber, Sara, Griveau, Audrey, Djebali, Sophia, Marcos, Elisabeth, Payen, Léa, Marvel, Jacqueline, Parent, Romain, Adnot, Serge, Bertolino, Philippe, Rieusset, Jennifer, Tortereau, Antonin, Vindrieux, David, Bernard, David
Publicado 2023

NF‐κB‐dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells

por Raynard, Clotilde, Ma, Xingjie, Huna, Anda, Tessier, Nolwenn, Massemin, Amélie, Zhu, Kexin, Flaman, Jean‐Michel, Moulin, Florentin, Goehrig, Delphine, Medard, Jean‐Jacques, Vindrieux, David, Treilleux, Isabelle, Hernandez‐Vargas, Hector, Ducreux, Sylvie, Martin, Nadine, Bernard, David
Publicado 2022

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging

por Huna, Anda, Griveau, Audrey, Vindrieux, David, Jaber, Sara, Flaman, Jean-Michel, Goehrig, Delphine, Azzi, Lamia, Médard, Jean-Jacques, Djebali, Sophia, Hernandez-Vargas, Hector, Dante, Robert, Payen, Léa, Marvel, Jacqueline, Bertolino, Philippe, Aubert, Sébastien, Dubus, Pierre, Bernard, David
Publicado 2021

Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging

por Ziegler, Dorian V., Vindrieux, David, Goehrig, Delphine, Jaber, Sara, Collin, Guillaume, Griveau, Audrey, Wiel, Clotilde, Bendridi, Nadia, Djebali, Sophia, Farfariello, Valerio, Prevarskaya, Natacha, Payen, Léa, Marvel, Jacqueline, Aubert, Sébastien, Flaman, Jean-Michel, Rieusset, Jennifer, Martin, Nadine, Bernard, David
Publicado 2021

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters

por Delval, Lou, Hantute-Ghesquier, Aline, Sencio, Valentin, Flaman, Jean Michel, Robil, Cyril, Angulo, Fabiola Silva, Lipskaia, Larissa, Çobanoğlu, Ozmen, Lacoste, Anne-Sophie, Machelart, Arnaud, Danneels, Adeline, Corbin, Mathieu, Deruyter, Lucie, Heumel, Séverine, Idziorek, Thierry, Séron, Karin, Sauve, Florent, Bongiovanni, Antonino, Prévot, Vincent, Wolowczuk, Isabelle, Belouzard, Sandrine, Saliou, Jean-Michel, Gosset, Philippe, Bernard, David, Rouillé, Yves, Adnot, Serge, Duterque-Coquillaud, Martine, Trottein, François
Publicado 2023