Countering immunotoxin immunogenicity

por Flavell, David J
Publicado 2016

Plant-Derived Type I Ribosome Inactivating Protein-Based Targeted Toxins: A Review of the Clinical Experience

por Flavell, David J., Flavell, Sopsamorn U.
Publicado 2022

Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins

por Giansanti, Francesco, Flavell, David J., Angelucci, Francesco, Fabbrini, Maria Serena, Ippoliti, Rodolfo
Publicado 2018

The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-Cell Leukaemia

por Flavell, David J., Holmes, Suzanne E., Warnes, Sarah L, Flavell, Sopsamorn U.
Publicado 2019

The Effect of Small Molecule Pharmacological Agents on the Triterpenoid Saponin Induced Endolysosomal Escape of Saporin and a Saporin-Based Immunotoxin in Target Human Lymphoma Cel...

por Wensley, Harrison J., Smith, Wendy S., Holmes, Suzanne E., Flavell, Sopsamorn U., Flavell, David J.
Publicado 2021

Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents

por Smith, Wendy S., Johnston, David A., Holmes, Suzanne E., Wensley, Harrison J., Flavell, Sopsamorn U., Flavell, David J.
Publicado 2019

A Flow Cytometric Method to Quantify the Endosomal Escape of a Protein Toxin to the Cytosol of Target Cells

por Wensley, Harrison J., Johnston, David A., Smith, Wendy S., Holmes, Suzanne E., Flavell, Sopsamorn U., Flavell, David J.
Publicado 2019

The Role of Cholesterol on Triterpenoid Saponin-Induced Endolysosomal Escape of a Saporin-Based Immunotoxin

por Smith, Wendy S., Johnston, David A., Wensley, Harrison J., Holmes, Suzanne E., Flavell, Sopsamorn U., Flavell, David J.
Publicado 2020

Antibody-Drug Conjugates: The New Frontier of Chemotherapy

por Ponziani, Sara, Di Vittorio, Giulia, Pitari, Giuseppina, Cimini, Anna Maria, Ardini, Matteo, Gentile, Roberta, Iacobelli, Stefano, Sala, Gianluca, Capone, Emily, Flavell, David J., Ippoliti, Rodolfo, Giansanti, Francesco
Publicado 2020

Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera

por Errico Provenzano, Alfredo, Posteri, Riccardo, Giansanti, Francesco, Angelucci, Francesco, Flavell, Sopsamorn U., Flavell, David J., Fabbrini, Maria Serena, Porro, Danilo, Ippoliti, Rodolfo, Ceriotti, Aldo, Branduardi, Paola, Vago, Riccardo
Publicado 2016

Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems

por Della Cristina, Pietro, Castagna, Monica, Lombardi, Alessio, Barison, Erika, Tagliabue, Giovanni, Ceriotti, Aldo, Koutris, Ilias, Di Leandro, Luana, Giansanti, Francesco, Vago, Riccardo, Ippoliti, Rodolfo, Flavell, Sopsamorn U, Flavell, David J, Colombatti, Marco, Fabbrini, Maria Serena
Publicado 2015