Direct observation of DNA threading in flap endonuclease complexes

por AlMalki, Faizah A, Flemming, Claudia S, Zhang, Jing, Feng, Min, Sedelnikova, Svetlana E, Ceska, Tom, Rafferty, John B, Sayers, Jon R, Artymiuk, Peter J
Publicado 2016

The structure of Escherichia coli ExoIX—implications for DNA binding and catalysis in flap endonucleases

por Anstey-Gilbert, Christopher S., Hemsworth, Glyn R., Flemming, Claudia S., Hodskinson, Michael R. G., Zhang, Jing, Sedelnikova, Svetlana E., Stillman, Timothy J., Sayers, Jon R., Artymiuk, Peter J.
Publicado 2013

MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma

por Lau, Diana T., Flemming, Claudia L., Gherardi, Samuele, Perini, Giovanni, Oberthuer, André, Fischer, Matthias, Juraeva, Dilafruz, Brors, Benedikt, Xue, Chengyuan, Norris, Murray D., Marshall, Glenn M., Haber, Michelle, Fletcher, Jamie I., Ashton, Lesley J.
Publicado 2015

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

por Henderson, Michelle J., Haber, Michelle, Porro, Antonio, Munoz, Marcia A., Iraci, Nunzio, Xue, Chengyuan, Murray, Jayne, Flemming, Claudia L., Smith, Janice, Fletcher, Jamie I., Gherardi, Samuele, Kwek, Chin-Kiat, Russell, Amanda J., Valli, Emanuele, London, Wendy B., Buxton, Allen B., Ashton, Lesley J., Sartorelli, Alan C., Cohn, Susan L., Schwab, Manfred, Marshall, Glenn M., Perini, Giovanni, Norris, Murray D.
Publicado 2011

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

por Somers, Klaartje, Wen, Victoria W., Middlemiss, Shiloh M. C., Osborne, Brenna, Forgham, Helen, Jung, MoonSun, Karsa, Mawar, Clifton, Molly, Bongers, Angelika, Gao, Jixuan, Mayoh, Chelsea, Raoufi-Rad, Newsha, Kusnadi, Eric P., Hannan, Kate M., Scott, David A., Kwek, Alan, Liu, Bing, Flemming, Claudia, Chudakova, Daria A., Pandher, Ruby, Failes, Tim W., Lim, James, Angeli, Andrea, Osterman, Andrei L., Imamura, Toshihiko, Kees, Ursula R., Supuran, Claudiu T., Pearson, Richard B., Hannan, Ross D., Davis, Thomas P., McCarroll, Joshua, Kavallaris, Maria, Turner, Nigel, Gudkov, Andrei V., Haber, Michelle, Norris, Murray D., Henderson, Michelle J.
Publicado 2019