Epigallocatechin-3-Gallate Accelerates Relaxation and Ca(2+) Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice

por Friedrich, Felix W., Flenner, Frederik, Nasib, Mahtab, Eschenhagen, Thomas, Carrier, Lucie
Publicado 2016

β(1) Adrenoceptor antagonistic effects of the supposedly selective β(2) adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts

por Pecha, Simon, Flenner, Frederik, Söhren, Klaus-Dieter, Lorenz, Kristina, Eschenhagen, Thomas, Christ, Torsten
Publicado 2015

I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model

por Friedrich, Felix W., Sotoud, Hannieh, Geertz, Birgit, Weber, Silvio, Flenner, Frederik, Reischmann, Silke, Eschenhagen, Thomas, Carrier, Lucie, El-Armouche, Ali
Publicado 2015

Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue

por Kresin, Nico, Stücker, Sabrina, Krämer, Elisabeth, Flenner, Frederik, Mearini, Giulia, Münch, Julia, Patten, Monica, Redwood, Charles, Carrier, Lucie, Friedrich, Felix W.
Publicado 2019

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium

por Lemme, Marta, Ulmer, Bärbel M., Lemoine, Marc D., Zech, Antonia T.L., Flenner, Frederik, Ravens, Ursula, Reichenspurner, Hermann, Rol-Garcia, Miriam, Smith, Godfrey, Hansen, Arne, Christ, Torsten, Eschenhagen, Thomas
Publicado 2018

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

por Prondzynski, Maksymilian, Krämer, Elisabeth, Laufer, Sandra D., Shibamiya, Aya, Pless, Ole, Flenner, Frederik, Müller, Oliver J., Münch, Julia, Redwood, Charles, Hansen, Arne, Patten, Monica, Eschenhagen, Thomas, Mearini, Giulia, Carrier, Lucie
Publicado 2017

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae

por Mannhardt, Ingra, Eder, Alexandra, Dumotier, Berengere, Prondzynski, Maksymilian, Krämer, Elisabeth, Traebert, Martin, Söhren, Klaus-Dieter, Flenner, Frederik, Stathopoulou, Konstantina, Lemoine, Marc D., Carrier, Lucie, Christ, Torsten, Eschenhagen, Thomas, Hansen, Arne
Publicado 2017

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

por Lemoine, Marc D., Mannhardt, Ingra, Breckwoldt, Kaja, Prondzynski, Maksymilian, Flenner, Frederik, Ulmer, Bärbel, Hirt, Marc N., Neuber, Christiane, Horváth, András, Kloth, Benjamin, Reichenspurner, Hermann, Willems, Stephan, Hansen, Arne, Eschenhagen, Thomas, Christ, Torsten
Publicado 2017

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

por Horváth, András, Lemoine, Marc D., Löser, Alexandra, Mannhardt, Ingra, Flenner, Frederik, Uzun, Ahmet Umur, Neuber, Christiane, Breckwoldt, Kaja, Hansen, Arne, Girdauskas, Evaldas, Reichenspurner, Hermann, Willems, Stephan, Jost, Norbert, Wettwer, Erich, Eschenhagen, Thomas, Christ, Torsten
Publicado 2018

Translational investigation of electrophysiology in hypertrophic cardiomyopathy

por Flenner, Frederik, Jungen, Christiane, Küpker, Nadine, Ibel, Antonia, Kruse, Martin, Koivumäki, Jussi T., Rinas, Anna, Zech, Antonia T.L., Rhoden, Alexandra, Wijnker, Paul J.M., Lemoine, Marc D., Steenpass, Anna, Girdauskas, Evaldas, Eschenhagen, Thomas, Meyer, Christian, van der Velden, Jolanda, Patten-Hamel, Monica, Christ, Torsten, Carrier, Lucie
Publicado 2021

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

por Cuello, Friederike, Knaust, Anika E, Saleem, Umber, Loos, Malte, Raabe, Janice, Mosqueira, Diogo, Laufer, Sandra, Schweizer, Michaela, van der Kraak, Petra, Flenner, Frederik, Ulmer, Bärbel M, Braren, Ingke, Yin, Xiaoke, Theofilatos, Konstantinos, Ruiz‐Orera, Jorge, Patone, Giannino, Klampe, Birgit, Schulze, Thomas, Piasecki, Angelika, Pinto, Yigal, Vink, Aryan, Hübner, Norbert, Harding, Sian, Mayr, Manuel, Denning, Chris, Eschenhagen, Thomas, Hansen, Arne
Publicado 2021