Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics

por Dyavar, Shetty Ravi, Mykris, Timothy M., Winchester, Lee C., Scarsi, Kimberly K., Fletcher, Courtney V., Podany, Anthony T.
Publicado 2020

ACE-2, TMPRSS2, and Neuropilin-1 Receptor Expression on Human Brain Astrocytes and Pericytes and SARS-CoV-2 Infection Kinetics

por Malik, Johid Reza, Acharya, Arpan, Avedissian, Sean N., Byrareddy, Siddappa N., Fletcher, Courtney V., Podany, Anthony T., Dyavar, Shetty Ravi
Publicado 2023

Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns

por Morsey, Brenda, Niu, Meng, Dyavar, Shetty Ravi, Fletcher, Courtney V., Lamberty, Benjamin G., Emanuel, Katy, Fangmeier, Anna, Fox, Howard S.
Publicado 2021

Normalization of cell associated antiretroviral drug concentrations with a novel RPP30 droplet digital PCR assay

por Dyavar, Shetty Ravi, Ye, Zhen, Byrareddy, Siddappa N., Scarsi, Kimberly K., Winchester, Lee C., Weinhold, Jonathan A., Fletcher, Courtney V., Podany, Anthony T.
Publicado 2018

Immuno-epidemiology and pathophysiology of coronavirus disease 2019 (COVID-19)

por Olwenyi, Omalla A., Dyavar, Shetty Ravi, Acharya, Arpan, Podany, Anthony T., Fletcher, Courtney V., Ng, Caroline L., Reid, St Patrick, Byrareddy, Siddappa N.
Publicado 2020

Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options

por Dyavar, Shetty Ravi, Singh, Rahul, Emani, Rohini, Pawar, Ganesh P., Chaudhari, Vinod D., Podany, Anthony T., Avedissian, Sean N., Fletcher, Courtney V., Salunke, Deepak B.
Publicado 2021

Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection

por Olwenyi, Omalla A., Johnson, Samuel D., Pandey, Kabita, Thurman, Michellie, Acharya, Arpan, Buch, Shilpa J., Fox, Howard S., Podany, Anthony T., Fletcher, Courtney V., Byrareddy, Siddappa N.
Publicado 2021

Real‐Time and Wireless Assessment of Adherence to Antiretroviral Therapy With Co‐Encapsulated Ingestion Sensor in HIV‐Infected Patients: A Pilot Study

por Daar, Eric S., Rosen, Marc I., Wang, Yan, Siqueiros, Lisa, Shen, Jie, Guerrero, Mario, Xiong, Di, Dao, John, Young, Todd, Corado, Katya, Fletcher, Courtney V., Liu, Honghu
Publicado 2019

Ingestible sensor system for measuring, monitoring and enhancing adherence to antiretroviral therapy: An open-label, usual care-controlled, randomised trial

por Liu, Honghu, Wang, Yan, Huang, Yilan, Xiong, Di, Shen, Jie, Siqueiros, Lisa, Bala, Veenu, Savage, George M., Guerrero, Mario, Corado, Katya, Rosen, Marc I., Fletcher, Courtney V., Daar, Eric S.
Publicado 2022

Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe

por Makita-Chingombe, Faithful, Podany, Anthony T., Mykris, Timothy, Muzambi, Farai, Browne, Richard W., Ocque, Andrew J., DiFrancesco, Robin, Winchester, Lee C., Fletcher, Courtney V., Mudzviti, Tinashe, Maponga, Charles C., Morse, Gene D.
Publicado 2021

Transplantation of CCR5∆32 Homozygous Umbilical Cord Blood in a Child With Acute Lymphoblastic Leukemia and Perinatally Acquired HIV Infection

por Rothenberger, Meghan, Wagner, John E, Haase, Ashley, Richman, Douglas, Grzywacz, Bartosz, Strain, Matthew, Lada, Steven, Estes, Jacob, Fletcher, Courtney V, Podany, Anthony T, Anderson, Jodi, Schmidt, Thomas, Wietgrefe, Steve, Schacker, Timothy, Verneris, Michael R
Publicado 2018

Therapeutic implications of SARS-CoV-2 dysregulation of the gut-brain-lung axis

por Johnson, Samuel D, Olwenyi, Omalla A, Bhyravbhatla, Namita, Thurman, Michellie, Pandey, Kabita, Klug, Elizabeth A, Johnston, Morgan, Dyavar, Shetty Ravi, Acharya, Arpan, Podany, Anthony T, Fletcher, Courtney V, Mohan, Mahesh, Singh, Kamal, Byrareddy, Siddappa N
Publicado 2021

Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS‐CoV‐2 Infection

por Bender Ignacio, Rachel A., Wohl, David A., Arends, Rosalin, Pilla Reddy, Venkatesh, Mu, Ying, Javan, Arzhang Cyrus, Hughes, Michael D., Eron, Joseph J., Currier, Judith S., Smith, Davey, Chew, Kara W., Gibbs, Michael, Fletcher, Courtney V.
Publicado 2022

Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection

por Fox, Howard S., Niu, Meng, Morsey, Brenda M., Lamberty, Benjamin G., Emanuel, Katy, Periyasamy, Palsamy, Callen, Shannon, Acharya, Arpan, Kubik, Gregory, Eudy, James, Guda, Chittibabu, Dyavar, Shetty Ravi, Fletcher, Courtney V., Byrareddy, Siddappa N., Buch, Shilpa
Publicado 2022

In-vitro Immunomodulatory activity of Azadirachta indica A.Juss. Ethanol: water mixture against HIV associated chronic CD4(+) T-cell activation/ exhaustion

por Olwenyi, Omalla A., Asingura, Bannet, Naluyima, Prossy, Anywar, Godwin Upoki, Nalunga, Justine, Nakabuye, Mariam, Semwogerere, Michael, Bagaya, Bernard, Cham, Fatim, Tindikahwa, Allan, Kiweewa, Francis, Lichter, Eliezer Z., Podany, Anthony T., Fletcher, Courtney V., Byrareddy, Siddappa N., Kibuuka, Hannah
Publicado 2021

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women

por Mulligan, Nikki, Schalkwijk, Stein, Best, Brookie M., Colbers, Angela, Wang, Jiajia, Capparelli, Edmund V., Moltó, José, Stek, Alice M., Taylor, Graham, Smith, Elizabeth, Hidalgo Tenorio, Carmen, Chakhtoura, Nahida, van Kasteren, Marjo, Fletcher, Courtney V., Mirochnick, Mark, Burger, David
Publicado 2016

LB2. Safety and Efficacy of Combination SARS-CoV-2 Monoclonal Neutralizing Antibodies (mAb) BRII-196 and BRII-198 in Non-Hospitalized COVID-19 Patients

por Evering, Teresa H, Giganti, Mark, Chew, Kara W, Hughes, Michael, Moser, Carlee, Wohl, David Alain, Currier, Judith, Eron, Joseph J, Javan, Arzhang, Margolis, David A, Zhu, Qing, D’Andrea, Ulises, Hoover, Keila, Mocherla, Bharat R, Fletcher, Courtney, Li, Jonathan, Smith, Davey, Daar, Eric
Publicado 2021

Persistent HIV-1 replication maintains the tissue reservoir during therapy

por Lorenzo-Redondo, Ramon, Fryer, Helen R., Bedford, Trevor, Kim, Eun-Young, Archer, John, Pond, Sergei L. Kosakovsky, Chung, Yoon-Seok, Penugonda, Sudhir, Chipman, Jeffrey, Fletcher, Courtney V., Schacker, Timothy W., Malim, Michael H., Rambaut, Andrew, Haase, Ashley T., McLean, Angela R., Wolinsky, Steven M.
Publicado 2016

CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques

por Harwood, Olivia E., Matschke, Lea M., Moriarty, Ryan V., Balgeman, Alexis J., Weaver, Abigail J., Ellis-Connell, Amy L., Weiler, Andrea M., Winchester, Lee C., Fletcher, Courtney V., Friedrich, Thomas C., Keele, Brandon F., O’Connor, David H., Lang, Jessica D., Reynolds, Matthew R., O’Connor, Shelby L.
Publicado 2023

CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection

por Harwood, Olivia E., Matschke, Lea M., Moriarty, Ryan V., Balgeman, Alexis J., Weaver, Abigail J., Ellis-Connell, Amy L., Weiler, Andrea M., Winchester, Lee C., Fletcher, Courtney V., Friedrich, Thomas C., Keele, Brandon F., O’Connor, David H., Lang, Jessica D., Reynolds, Matthew R., O’Connor, Shelby L.
Publicado 2023