Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis

por Cluxton, Deborah, Petrasca, Andreea, Moran, Barry, Fletcher, Jean M.
Publicado 2019

Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators

por Hambly, Roisin, Kearney, Niamh, Hughes, Rosalind, Fletcher, Jean M., Kirby, Brian
Publicado 2023

Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1

por Campbell, Nicole K., Fitzgerald, Hannah K., Fletcher, Jean M., Dunne, Aisling
Publicado 2019

Inflammation in the pathogenesis of depression: a disorder of neuroimmune origin

por Corrigan, Myles, O'Rourke, Aoife M., Moran, Barry, Fletcher, Jean M., Harkin, Andrew
Publicado 2023

The Pathogenesis of Parkinson's Disease: A Complex Interplay Between Astrocytes, Microglia, and T Lymphocytes?

por MacMahon Copas, Adina N., McComish, Sarah F., Fletcher, Jean M., Caldwell, Maeve A.
Publicado 2021

Increased expression of Tbet in CD4(+) T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS

por Basdeo, Sharee A., Kelly, Siobhan, O’Connell, Karen, Tubridy, Niall, McGuigan, Christopher, Fletcher, Jean M.
Publicado 2016

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

por Campbell, Nicole K., Fitzgerald, Hannah K., Malara, Anna, Hambly, Roisin, Sweeney, Cheryl M., Kirby, Brian, Fletcher, Jean M., Dunne, Aisling
Publicado 2018

The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis

por Barker, Brianne E., Hanlon, Megan M., Marzaioli, Viviana, Smith, Conor M., Cunningham, Clare C., Fletcher, Jean M., Veale, Douglas J., Fearon, Ursula, Canavan, Mary
Publicado 2023

Innate lymphoid cell (ILC) subsets are enriched in the skin of patients with hidradenitis suppurativa

por Petrasca, Andreea, Hambly, Roisin, Molloy, Oonagh, Kearns, Sean, Moran, Barry, Smith, Conor M., Hughes, Rosalind, O’Donnell, Margaret, Zaborowski, Alexandra, Winter, Desmond, Fletcher, Jean M., Kirby, Brian, Malara, Anna
Publicado 2023

CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

por Hoare, Matthew, Gelson, William T.H., Das, Abhi, Fletcher, Jean M., Davies, Susan E., Curran, Martin D., Vowler, Sarah L., Maini, Mala K., Akbar, Arne N., Alexander, Graeme J.M.
Publicado 2010

Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of...

por Dunne, Margaret R., Ryan, Ciara, Nolan, Bláthnaid, Tosetto, Miriam, Geraghty, Robert, Winter, Des C., O’Connell, P. Ronan, Hyland, John M., Doherty, Glen A., Sheahan, Kieran, Ryan, Elizabeth J., Fletcher, Jean M.
Publicado 2016

The Trypanosoma brucei-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells

por Fitzgerald, Hannah K., O’Rourke, Sinead A., Desmond, Eva, Neto, Nuno G. B., Monaghan, Michael G., Tosetto, Miriam, Doherty, Jayne, Ryan, Elizabeth J., Doherty, Glen A., Nolan, Derek P., Fletcher, Jean M., Dunne, Aisling
Publicado 2022

Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy

por Gaynor, Nicola, Blanco, Alfonso, Madden, Stephen F., Moran, Barry, Fletcher, Jean M., Kaukonen, Damien, Ramírez, Javier Sánchez, Eustace, Alex J., McDermott, Martina S. J., Canonici, Alexandra, Toomey, Sinead, Teiserskiene, Ausra, Hennessy, Bryan T., O’Donovan, Norma, Crown, John, Collins, Denis M.
Publicado 2023

Telomere Erosion in Memory T Cells Induced by Telomerase Inhibition at the Site of Antigenic Challenge In Vivo

por Reed, John R., Vukmanovic-Stejic, Milica, Fletcher, Jean M., Soares, Maria Vieira D., Cook, Joanne E., Orteu, Catherine H., Jackson, Sarah E., Birch, Katie E., Foster, Graham R., Salmon, Mike, Beverley, Peter C.L., Rustin, Malcolm H.A., Akbar, Arne N.
Publicado 2004

Effects of vitamin D(3) in clinically isolated syndrome and healthy control participants: A double-blind randomised controlled trial

por O’Connell, Karen, Sulaimani, Jamal, Basdeo, Sharee A, Kinsella, Katie, Jordan, Sinead, Kenny, Orla, Kelly, Siobhan B, Murphy, David, Heffernan, Eric, Killeen, Ronan P, Mulready, Keith, MacMahon, Marguerite, Brady, Jennifer J, McKenna, Carmel, Muldowney, Ciaran, Cassidy, Lorraine, Walsh, Cathal, O’Rourke, Killian, Tubridy, Niall, McGuigan, Chris, Fletcher, Jean M, Hutchinson, Michael
Publicado 2017