Overcoming heterogenity in imatinib-resistant gastrointestinal stromal tumor

por Serrano, César, Fletcher, Jonathan A.
Publicado 2019

After Nf1 loss in Schwann cells, inflammation drives neurofibroma formation

por Fletcher, Jonathan S, Pundavela, Jay, Ratner, Nancy
Publicado 2019

The commonly-used DNA probe for diffusely-adherent Escherichia coli cross-reacts with a subset of enteroaggregative E. coli

por Snelling, Anna M, Macfarlane-Smith, Louissa R, Fletcher, Jonathan N, Okeke, Iruka N
Publicado 2009

IS3 profiling identifies the enterohaemorrhagic Escherichia coli O-island 62 in a distinct enteroaggregative E. coli lineage

por Okeke, Iruka N, Macfarlane-Smith, Louissa R, Fletcher, Jonathan N, Snelling, Anna M
Publicado 2011

The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma

por Wu, Xinqi, Zhu, Meijun, Fletcher, Jonathan A., Giobbie-Hurder, Anita, Hodi, F. Stephen
Publicado 2012

Comparative Gene Expression Profiling of Benign and Malignant Lesions Reveals Candidate Therapeutic Compounds for Leiomyosarcoma

por Edris, Badreddin, Fletcher, Jonathan A., West, Robert B., van de Rijn, Matt, Beck, Andrew H.
Publicado 2012

Inhibition of KIT-Glycosylation by 2-Deoxyglucose Abrogates KIT-Signaling and Combination with ABT-263 Synergistically Induces Apoptosis in Gastrointestinal Stromal Tumor

por Mühlenberg, Thomas, Grunewald, Susanne, Treckmann, Jürgen, Podleska, Lars, Schuler, Martin, Fletcher, Jonathan A., Bauer, Sebastian
Publicado 2015

An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system

por Choi, Kwangmin, Komurov, Kakajan, Fletcher, Jonathan S., Jousma, Edwin, Cancelas, Jose A., Wu, Jianqiang, Ratner, Nancy
Publicado 2017

Anisotropic Magnetoresistance State Space of Permalloy Nanowires with Domain Wall Pinning Geometry

por Corte-León, Héctor, Nabaei, Vahid, Manzin, Alessandra, Fletcher, Jonathan, Krzysteczko, Patryk, Schumacher, Hans W., Kazakova, Olga
Publicado 2014

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

por Nakayama, Robert, Zhang, Yi-Xiang, Czaplinski, Jeffrey T., Anatone, Alex J., Sicinska, Ewa T., Fletcher, Jonathan A., Demetri, George D., Wagner, Andrew J.
Publicado 2016

STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma

por Fletcher, Jonathan S., Springer, Mitchell G., Choi, Kwangmin, Jousma, Edwin, Rizvi, Tilat A., Dombi, Eva, Kim, Mi-Ok, Wu, Jianqiang, Ratner, Nancy
Publicado 2018

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

por Hsueh, Yuan-Shuo, Chang, Hui Hua, Shan, Yan-Shen, Sun, H. Sunny, Fletcher, Jonathan Alfred, Li, Chien-Feng, Chen, Li-Tzong
Publicado 2019

YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways

por Ou, Wen-Bin, Lundberg, Meijun Z., Zhu, Shuihao, Bahri, Nacef, Kyriazoglou, Anastasios, Xu, Liangliang, Chen, Ting, Mariño-Enriquez, Adrian, Fletcher, Jonathan A.
Publicado 2021

Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3

por Yang, Peipei, Chen, Weicai, Li, Xuhui, Eilers, Grant, He, Quan, Liu, Lili, Wu, Yeqing, Wu, Yuehong, Yu, Wei, Fletcher, Jonathan A., Ou, Wen-Bin
Publicado 2016

AXL Inactivation Inhibits Mesothelioma Growth and Migration via Regulation of p53 Expression

por Song, Wei, Wang, Hao, Lu, Minmin, Ni, Xinxin, Bahri, Nacef, Zhu, Shuihao, Chen, Limin, Wu, Yuehong, Qiu, Jieqiong, Fletcher, Jonathan A., Ou, Wen-Bin
Publicado 2020

Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53

por Ou, Wen-Bin, Lu, Minmin, Eilers, Grant, Li, Hailong, Ding, Jiongyan, Meng, Xuli, Wu, Yuehong, He, Quan, Sheng, Qing, Zhou, Hai-Meng, Fletcher, Jonathan A
Publicado 2016

p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

por Henze, Joern, Mühlenberg, Thomas, Simon, Susanne, Grabellus, Florian, Rubin, Brian, Taeger, Georg, Schuler, Martin, Treckmann, Juergen, Debiec-Rychter, Maria, Taguchi, Takahiro, Fletcher, Jonathan A., Bauer, Sebastian
Publicado 2012

Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor

por Katz, Steven C, Burga, Rachel A, Naheed, Seema, Licata, Lauren A, Thorn, Mitchell, Osgood, Doreen, Nguyen, Cang T, Espat, N Joseph, Fletcher, Jonathan A, Junghans, Richard P
Publicado 2013

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

por Falkenhorst, Johanna, Grunewald, Susanne, Mühlenberg, Thomas, Marino-Enriquez, Adrian, Reis, Anna-Carina, Corless, Christopher, Heinrich, Michael, Treckmann, Jürgen, Podleska, Lars Erik, Schuler, Martin, Fletcher, Jonathan Alfred, Bauer, Sebastian
Publicado 2016

LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma

por Klug, Lillian R., Bannon, Amber E., Javidi-Sharifi, Nathalie, Town, Ajia, Fleming, William H., VanSlyke, Judy, Musil, Linda, Fletcher, Jonathan A., Tyner, Jeffrey W., Heinrich, Michael C.
Publicado 2018