Retinal Ganglion Cell Diversity and Subtype Specification from Human Pluripotent Stem Cells

por Langer, Kirstin B., Ohlemacher, Sarah K., Phillips, M. Joseph, Fligor, Clarisse M., Jiang, Peng, Gamm, David M., Meyer, Jason S.
Publicado 2018

Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids

por Fligor, Clarisse M., Lavekar, Sailee S., Harkin, Jade, Shields, Priya K., VanderWall, Kirstin B., Huang, Kang-Chieh, Gomes, Cátia, Meyer, Jason S.
Publicado 2021

Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma

por Huang, Kang-Chieh, Gomes, Cátia, Shiga, Yukihiro, Belforte, Nicolas, VanderWall, Kirstin B., Lavekar, Sailee S., Fligor, Clarisse M., Harkin, Jade, Di Polo, Adriana, Meyer, Jason S.
Publicado 2023

Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells

por Gomes, Cátia, VanderWall, Kirstin B., Pan, Yanling, Lu, Xiaoyu, Lavekar, Sailee S., Huang, Kang-Chieh, Fligor, Clarisse M., Harkin, Jade, Zhang, Chi, Cummins, Theodore R., Meyer, Jason S.
Publicado 2022

Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

por VanderWall, Kirstin B., Vij, Ridhima, Ohlemacher, Sarah K., Sridhar, Akshayalakshmi, Fligor, Clarisse M., Feder, Elyse M., Edler, Michael C., Baucum, Anthony J., Cummins, Theodore R., Meyer, Jason S.
Publicado 2019

Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells

por Fligor, Clarisse M., Langer, Kirstin B., Sridhar, Akshayalakshmi, Ren, Yuan, Shields, Priya K., Edler, Michael C., Ohlemacher, Sarah K., Sluch, Valentin M., Zack, Donald J., Zhang, Chi, Suter, Daniel M., Meyer, Jason S.
Publicado 2018

Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids

por VanderWall, Kirstin B., Huang, Kang-Chieh, Pan, Yanling, Lavekar, Sailee S., Fligor, Clarisse M., Allsop, Anna R., Lentsch, Kelly A., Dang, Pengtao, Zhang, Chi, Tseng, Henry C., Cummins, Theodore R., Meyer, Jason S.
Publicado 2020