Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

por Blanter, Marfa, Sork, Helena, Tuomela, Soile, Flodström-Tullberg, Malin
Publicado 2019

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins

por Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu
Publicado 2020

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

por Edlund, Anna, Esguerra, Jonathan LS, Wendt, Anna, Flodström-Tullberg, Malin, Eliasson, Lena
Publicado 2014

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

por Edlund, Anna, Pedersen, Morten Gram, Lindqvist, Andreas, Wierup, Nils, Flodström-Tullberg, Malin, Eliasson, Lena
Publicado 2017

Inhibition of Type III Interferon Expression in Intestinal Epithelial Cells—A Strategy Used by Coxsackie B Virus to Evade the Host’s Innate Immune Response at the Primary Site of I...

por Stone, Virginia M., Ringqvist, Emma E., Larsson, Pär G., Domsgen, Erna, Holmlund, Ulrika, Sverremark-Ekström, Eva, Flodström-Tullberg, Malin
Publicado 2021

Protection Against Type 1 Diabetes Upon Coxsackievirus B4 Infection and iNKT-Cell Stimulation: Role of Suppressive Macrophages

por Ghazarian, Liana, Diana, Julien, Beaudoin, Lucie, Larsson, Pär G., Puri, Raj K., van Rooijen, Nico, Flodström-Tullberg, Malin, Lehuen, Agnès
Publicado 2013

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

por Stone, Virginia M., Butrym, Marta, Hankaniemi, Minna M., Sioofy-Khojine, Amir-Babak, Hytönen, Vesa P., Hyöty, Heikki, Flodström-Tullberg, Malin
Publicado 2021

Proteome profiling of whole plasma and plasma-derived extracellular vesicles facilitates the detection of tissue biomarkers in the non-obese diabetic mouse

por Diaz Lozano, Isabel M., Sork, Helena, Stone, Virginia M., Eldh, Maria, Cao, Xiaofang, Pernemalm, Maria, Gabrielsson, Susanne, Flodström-Tullberg, Malin
Publicado 2022

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

por Domsgen, Erna, Lind, Katharina, Kong, Lingjia, Hühn, Michael H., Rasool, Omid, van Kuppeveld, Frank, Korsgren, Olle, Lahesmaa, Riitta, Flodström-Tullberg, Malin
Publicado 2016

The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas

por Kayali, Ayse G., Van Gunst, Kurt, Campbell, Iain L., Stotland, Aleksandr, Kritzik, Marcie, Liu, Guoxun, Flodström-Tullberg, Malin, Zhang, You-Qing, Sarvetnick, Nora
Publicado 2003

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

por Stone, Virginia M., Hankaniemi, Minna M., Svedin, Emma, Sioofy-Khojine, Amirbabak, Oikarinen, Sami, Hyöty, Heikki, Laitinen, Olli H., Hytönen, Vesa P., Flodström-Tullberg, Malin
Publicado 2017

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

por Saarinen, Niila V. V., Stone, Virginia M., Hankaniemi, Minna M., Mazur, Magdalena A., Vuorinen, Tytti, Flodström-Tullberg, Malin, Hyöty, Heikki, Hytönen, Vesa P., Laitinen, Olli H.
Publicado 2020

Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells

por Lietzén, Niina, Hirvonen, Karoliina, Honkimaa, Anni, Buchacher, Tanja, Laiho, Jutta E., Oikarinen, Sami, Mazur, Magdalena A., Flodström-Tullberg, Malin, Dufour, Eric, Sioofy-Khojine, Amir-Babak, Hyöty, Heikki, Lahesmaa, Riitta
Publicado 2019

Corona Pandemic: Assisted Isolation and Care to Protect Vulnerable Populations May Allow Us to Shorten the Universal Lock-Down and Gradually Re-open Society

por Ludvigsson, Johnny, von Herrath, Matthias G., Mallone, Roberto, Buschard, Karsten, Cilio, Corrado, Craig, Maria, Ilonen, Jorma, Leslie, David, McGeoch, Julie E. M., Schneider, Darius, Skyler, Jay S., Flodström Tullberg, Malin, Hober, Didier
Publicado 2020

Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes

por Dunne, Jessica L., Richardson, Sarah J., Atkinson, Mark A., Craig, Maria E., Dahl-Jørgensen, Knut, Flodström-Tullberg, Malin, Hyöty, Heikki, Insel, Richard A., Lernmark, Åke, Lloyd, Richard E., Morgan, Noel G., Pugliese, Alberto
Publicado 2019

Defining the proteolytic landscape during enterovirus infection

por Saeed, Mohsan, Kapell, Sebastian, Hertz, Nicholas T., Wu, Xianfang, Bell, Kierstin, Ashbrook, Alison W., Mark, Milica Tesic, Zebroski, Henry A., Neal, Maxwell L., Flodström-Tullberg, Malin, MacDonald, Margaret R., Aitchison, John D., Molina, Henrik, Rice, Charles M.
Publicado 2020

Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination

por Stone, Virginia M., Utorova, Renata, Butrym, Marta, Sioofy-Khojine, Amir-Babak, Hankaniemi, Minna M., Ringqvist, Emma E., Blanter, Marfa, Parajuli, Anirudra, Pincikova, Terezia, Fischler, Björn, Karpati, Ferenc, Hytönen, Vesa P., Hyöty, Heikki, Hjelte, Lena, Flodström-Tullberg, Malin
Publicado 2022

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense

por Svedin, Emma, Utorova, Renata, Hühn, Michael H, Larsson, Pär G, Stone, Virginia M, Garimella, Manasa, Lind, Katharina, Hägglöf, Thomas, Pincikova, Terezia, Laitinen, Olli H, McInerney, Gerald M, Scholte, Bob, Hjelte, Lena, Karlsson, Mikael C I, Flodström-Tullberg, Malin
Publicado 2017

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses

por Saarinen, Niila V. V., Laiho, Jutta E., Richardson, Sarah J., Zeissler, Marie, Stone, Virginia M., Marjomäki, Varpu, Kantoluoto, Tino, Horwitz, Marc S., Sioofy-Khojine, Amirbabak, Honkimaa, Anni, Hankaniemi, Minna M., Flodström-Tullberg, Malin, Hyöty, Heikki, Hytönen, Vesa P., Laitinen, Olli H.
Publicado 2018

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

por Khan, Dawood, Kelsey, Ryan, Maheshwari, Rashmi R., Stone, Virginia M., Hasib, Annie, Manderson Koivula, Fiona N., Watson, Aoife, Harkin, Stephen, Irwin, Nigel, Shaw, James A., McClenaghan, Neville H., Venglovecz, Viktória, Ébert, Attila, Flodström-Tullberg, Malin, White, Michael G., Kelly, Catriona
Publicado 2019