IL-10-IFN-γ Double Producers CD4+ T Cells Are Induced by Immunization with an Amastigote Stage Specific Derived Recombinant Protein of Trypanosoma Cruzi

por Flores-García, Yevel, Rosales-Encina, José Luis, Satoskar, Abhay R., Talamás-Rohana, Patricia
Publicado 2011

Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection

por Sahu, Tejram, Gehrke, Ella J., Flores-Garcia, Yevel, Mlambo, Godfree, Romano, Julia D., Coppens, Isabelle
Publicado 2021

A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

por Jelínková, Lucie, Flores-Garcia, Yevel, Shapiro, Sarah, Roberts, Bryce T., Petrovsky, Nikolai, Zavala, Fidel, Chackerian, Bryce
Publicado 2022

Antibody-Mediated Protection against Plasmodium Sporozoites Begins at the Dermal Inoculation Site

por Flores-Garcia, Yevel, Nasir, Gibran, Hopp, Christine S., Munoz, Christian, Balaban, Amanda E., Zavala, Fidel, Sinnis, Photini
Publicado 2018

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages

por Flores-Garcia, Yevel, Herrera, Sonia M., Jhun, Hugo, Pérez-Ramos, Daniel W., King, C. Richter, Locke, Emily, Raghunandan, Ramadevi, Zavala, Fidel
Publicado 2019

Maternal Immune Response During Pregnancy and Vertical Transmission in Human Toxoplasmosis

por Gómez-Chávez, Fernando, Cañedo-Solares, Irma, Ortiz-Alegría, Luz Belinda, Flores-García, Yevel, Luna-Pastén, Héctor, Figueroa-Damián, Ricardo, Mora-González, Juan Carlos, Correa, Dolores
Publicado 2019

The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo

por Flores-Garcia, Yevel, Wang, Lawrence T., Park, Minah, Asady, Beejan, Idris, Azza H., Kisalu, Neville K., Muñoz, Christian, Pereira, Lais S., Francica, Joseph R., Seder, Robert A., Zavala, Fidel
Publicado 2021

Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus

por Urakami, Akane, Sakurai, Atsuko, Ishikawa, Momoko, Yap, Moh Lan, Flores-Garcia, Yevel, Haseda, Yasunari, Aoshi, Taiki, Zavala, Fidel P., Rossmann, Michael G., Kuno, Sachiko, Ueno, Ryuji, Akahata, Wataru
Publicado 2017

Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

por Raghunandan, Rama, Mayer, Bryan T., Flores-Garcia, Yevel, Gerber, Monica W., Gottardo, Raphael, Jhun, Hugo, Herrera, Sonia M., Perez-Ramos, Daniel W., Locke, Emily, King, C. Richter, Zavala, Fidel
Publicado 2020

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

por Pholcharee, Tossapol, Oyen, David, Flores-Garcia, Yevel, Gonzalez-Paez, Gonzalo, Han, Zhen, Williams, Katherine L., Volkmuth, Wayne, Emerling, Daniel, Locke, Emily, Richter King, C., Zavala, Fidel, Wilson, Ian A.
Publicado 2021

Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein

por Oyen, David, Torres, Jonathan L., Wille-Reece, Ulrike, Ockenhouse, Christian F., Emerling, Daniel, Glanville, Jacob, Volkmuth, Wayne, Flores-Garcia, Yevel, Zavala, Fidel, Ward, Andrew B., King, C. Richter, Wilson, Ian A.
Publicado 2017

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein

por Pholcharee, Tossapol, Oyen, David, Torres, Jonathan L., Flores-Garcia, Yevel, Martin, Gregory M., González-Páez, Gonzalo E., Emerling, Daniel, Volkmuth, Wayne, Locke, Emily, King, C. Richter, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
Publicado 2020

Engineered DNA-encoded monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein confer single dose protection in a murine malaria challenge model

por Tursi, Nicholas J., Reeder, Sophia M., Flores-Garcia, Yevel, Bah, Mamadou A., Mathis-Torres, Shamika, Salgado-Jimenez, Berenice, Esquivel, Rianne, Xu, Ziyang, Chu, Jacqueline D., Humeau, Laurent, Patel, Ami, Zavala, Fidel, Weiner, David B.
Publicado 2022

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

por Thai, Elaine, Costa, Giulia, Weyrich, Anna, Murugan, Rajagopal, Oyen, David, Flores-Garcia, Yevel, Prieto, Katherine, Bosch, Alexandre, Valleriani, Angelo, Wu, Nicholas C., Pholcharee, Tossapol, Scally, Stephen W., Wilson, Ian A., Wardemann, Hedda, Julien, Jean-Philippe, Levashina, Elena A.
Publicado 2020

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention

por Kisalu, Neville K., Pereira, Lais D., Ernste, Keenan, Flores-Garcia, Yevel, Idris, Azza H., Asokan, Mangaiarkarasi, Dillon, Marlon, MacDonald, Scott, Shi, Wei, Chen, Xuejun, Pegu, Amarendra, Schön, Arne, Zavala, Fidel, Balazs, Alejandro B., Francica, Joseph R., Seder, Robert A.
Publicado 2021

A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns

por Gómez-Chávez, Fernando, Cañedo-Solares, Irma, Ortiz-Alegría, Luz Belinda, Flores-García, Yevel, Figueroa-Damián, Ricardo, Luna-Pastén, Héctor, Gómez-Toscano, Valeria, López-Candiani, Carlos, Arce-Estrada, G. Emmanuel, Bonilla-Ríos, Christian A., Mora-González, Juan Carlos, García-Ruiz, Ricardo, Correa, Dolores
Publicado 2020

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

por Oyen, David, Torres, Jonathan L., Aoto, Phillip C., Flores-Garcia, Yevel, Binter, Špela, Pholcharee, Tossapol, Carroll, Sean, Reponen, Sini, Wash, Rachael, Liang, Qi, Lemiale, Franck, Locke, Emily, Bradley, Allan, King, C. Richter, Emerling, Daniel, Kellam, Paul, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
Publicado 2020

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

por Martin, Gregory M., Torres, Jonathan L., Pholcharee, Tossapol, Oyen, David, Flores-Garcia, Yevel, Gibson, Grace, Moskovitz, Re’em, Beutler, Nathan, Jung, Diana D., Copps, Jeffrey, Lee, Wen-Hsin, Gonzalez-Paez, Gonzalo, Emerling, Daniel, MacGill, Randall S., Locke, Emily, King, C. Richter, Zavala, Fidel, Wilson, Ian A., Ward, Andrew B.
Publicado 2023

High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire

por Kucharska, Iga, Binter, Špela, Murugan, Rajagopal, Scally, Stephen W., Ludwig, Julia, Prieto, Katherine, Thai, Elaine, Costa, Giulia, Li, Kan, Horn, Gillian Q., Flores-Garcia, Yevel, Bosch, Alexandre, Sicard, Taylor, Rubinstein, John L., Zavala, Fidel, Dennison, S. Moses, Tomaras, Georgia D., Levashina, Elena A., Kellam, Paul, Wardemann, Hedda, Julien, Jean-Philippe
Publicado 2022

Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection

por Aguirre-Botero, Manuela C., Wang, Lawrence T., Formaglio, Pauline, Aliprandini, Eduardo, Thiberge, Jean-Michel, Schön, Arne, Flores-Garcia, Yevel, Mathis-Torres, Shamika, Flynn, Barbara J., da Silva Pereira, Lais, Le Duff, Yann, Hurley, Mathew, Nacer, Adéla, Bowyer, Paul W., Zavala, Fidel, Idris, Azza H., Francica, Joseph R., Seder, Robert A., Amino, Rogerio
Publicado 2023